Results 61 to 70 of about 689,003 (314)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Treatment of Aspergillosis

Journal of Fungi, 2018
Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Jeffrey D. Jenks, Martin Hoenigl
doaj   +1 more source

Matrix Metalloproteinase 9 (MMP-9) and Interleukin-8 (IL-8) in Gingival Crevicular Fluid after Regenerative Therapy in Periodontal Intrabony Defects with and without Systemic Antibiotics—Randomized Clinical Trial

Pathogens, 2022
The aim of our study was to assess changes in the levels of IL-8 and MMP-9 in gingival crevicular fluid (GCF) collected from the periodontal pocket before and after regenerative surgery with deproteinized bovine bone mineral (DBBM) and collagen membrane (
Ewa Dolińska, Małgorzata Pietruska, Violetta Dymicka-Piekarska, Robert Milewski, Anton Sculean   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Effect of Epidermal Growth Factor and Cyclosporin A on InterIeukin-8 Gene Expression in Human Aortic Smooth Muscle Cells [PDF]

, 2002
2002-12It was reported that accelerated allograft atherosclerosis is associated with usage of cyclosporin A (CsA). Although the immunosuppressive actions of CsA are extensively studied, the mechanisms of this adverse effect remains to be elucidated.
KAMBE, Fukushi, MURAKAMI, Ryuichiro, MITSUYAMA, Hirohito, YAMAMOTO, Ryohei, NIWATA, Satoru, SEO, Hisao, OKUMURA, Kenji   +6 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Early production of IL-22 but not IL-17 by peripheral blood mononuclear cells exposed to live Borrelia burgdorferi: the role of monocytes and interleukin-1 [PDF]

, 2010
If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine storm
Nicole Darsow, Kind, Peter, Rudloff, Ina, Klaus-Peter Hunfeld, Katharina Horn, Itamar Goren, Urs Christen, Kraiczy Peter, Horn Katharina, Pfeilschifter, Josef (Prof. Dr.), Mühl Heiko, Koehl Ulrike, Peter Kind, Goren Itamar, Pfeilschifter, Josef, Peter Kraiczy, Rudloff Ina, Goren, Itamar, Mühl, Heiko, Darsow, Nicole, Christen Urs, Kraiczy, Peter, Christen, Urs, Holdener, Martin, Horn, Katharina, Hunfeld, Klaus-Peter, Ulrike Koehl, Hunfeld Klaus-Peter, Heiko Mühl, Ina Rudloff, Malte Bachmann, Martin Holdener, Holdener Martin, Koehl, Ulricke, Bachmann Malte, Darsow Nicole, Kind Peter, Köhl, Ulrike, Josef Pfeilschifter, Bachmann, Malte, Pfeilschifter Josef   +40 more
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain [PDF]

, 2012
Background: Cytokines such as interleukin 6 (IL-6) have been implicated in dual functions in neuropsychiatric disorders. Little is known about the genetic predisposition to neurodegenerative and neuroproliferative properties of cytokine genes.
Domschke, Katharina, Volker Arolt, Walter Heindel, Katharina Domschke, Schoening, Sonja, Bernhard T Baune, Jochen Bauer, Christina Uhlmann, Arolt, V, Heindel, W., Konrad, Carsten, Domschke Katharina, Rauch, AV, Konrad Carsten, Suslow Thomas, Sonja Schöning, Kugel, H., Kugel, Harald, Heindel, W, Heindel, Walter, Konrad, C, Domschke, K, Uhlmann, C., Birosova, E, Udo Dannlowski, Suslow, T., Konrad, C., Baune, Bernhard T., Ohrmann Patricia, Uhlmann, C, Grotegerd Dominik, Patricia Ohrmann, Thomas Suslow, Ohrmann, P, Baune, B., Harald Kugel, Rauch, Astrid V., Astrid V Rauch, Grotegerd, D., Birosova Eva, Dannlowski Udo, Rauch Astrid V, Dannlowski, U, Kugel Harald, Birosova, E., Bauer, Jochen, Grotegerd, D, Grotegerd, Dominik, Arolt Volker, Rauch, A., Suslow, T, Uhlmann Christina, Dannlowski, U., Schöning Sonja, Bauer, J., Eva Birosova, Ohrmann, Patricia, Suslow, Thomas, Birosova, Eva, Kugel, H, Bauer, J, Ohrmann, P., Carsten Konrad, Schoning, S., Baune Bernhard T, Schöning, Sonja, Arolt, Volker, Arolt, V., Uhlmann, Christina, Dannlowski, Udo, Bauer Jochen, Domschke, K., Dominik Grotegerd, Baune, BT, Heindel Walter, Schöning, S   +75 more
core   +2 more sources

Adenosine-dependent regulation of paracrine factors expression in human venous blood monocytes

Бюллетень сибирской медицины, 2011
The flow cytometry analysis of human peripheral blood monocytes separated by a two step density gradient centrifugation is reported. The expression of mRNA level of adenosine receptor (AdoR) subtypes (A1, A2A, A2B and A3) and interleukin 6 (IL-6 ...
S. V. Ryzhov, K. S. Yuryeva, K. V. Goremykin, Ye. V. Korotkaya, I. V. Saltykova, Yu. A. Yakovleva, Ye. S. Kulikov, O. S. Fyodorova, Ye. E. Kremer, N. S. Fattakhov, A. E. Sazonov   +10 more
doaj   +1 more source