Interleukins and Ischemic Stroke
Frontiers in Immunology, 2022 Ischemic stroke after cerebral artery occlusion is one of the major causes of chronic disability worldwide. Interleukins (ILs) play a bidirectional role in ischemic stroke through information transmission, activation and regulation of immune cells ...
Hua Zhu +10 more
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Challenging the Paradigm: Anti-Inflammatory Interleukins and Angiogenesis
Cells, 2022 Angiogenesis is a vital biological process, and neovascularization is essential for the development, wound repair, and perfusion of ischemic tissue. Neovascularization and inflammation are independent biological processes that are linked in response to ...
Amanda M. Peluzzo, Michael V. Autieri
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Role of interleukins in the pathogenesis of pulmonary fibrosis
Cell Death Discovery, 2021 Interleukins, a group of cytokines participating in inflammation and immune response, are proved to be involved in the formation and development of pulmonary fibrosis.
Yi Xin She, Qing Yang Yu, Xiao Xiao Tang
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The roles and clinical applications of interleukins in endometrial carcinoma
Frontiers in Oncology, 2022 As a common malignant tumor of the female reproductive system, endometrial carcinoma (EC) seriously endangers women’s health with an increasing incidence. The oncogenesis and progression of cancer are closely linked with immune microenvironment, of which
Yuqin Zang +14 more
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Targeting Certain Interleukins as Novel Treatment Options for Liver Fibrosis
Frontiers in Pharmacology, 2021 The liver is a major metabolic organ and an immunologically complex organ. It produces and uses many substances such as acute phase proteins, cytokines, chemokines, and complementary components to maintain the balance between immunity and tolerance ...
Su Yeon An +4 more
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The Interleukins Orchestrate Mucosal Immune Responses to Salmonella Infection in the Intestine
Cells, 2021 Salmonella infection remains one of the major public health problems in the world, with increasing resistance to antibiotics. The resolution is to explore the pathogenesis of the infection and search for alternative therapy other than antibiotics. Immune
Fu-Chen Huang
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Interleukins in Thyroid Cancer: From Basic Researches to Applications in Clinical Practice
Frontiers in Immunology, 2020 Inflammation is crucial to tumorigenesis and progression of many cancers. Inflammatory molecules in tumor microenvironment exert pro- or anti-tumor effects.
Chuang Xi +8 more
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Causal analysis between altered levels of interleukins and obstructive sleep apnea
Frontiers in Immunology, 2022 BackgroundInflammation proteins including interleukins (ILs) have been reported to be related to obstructive sleep apnea (OSA). The aims of this study were to estimate the levels for several key interleukins in OSA and the causal effects between them ...
Minhan Yi +15 more
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Exploring causal associations between interleukins, their receptors, and acute respiratory distress syndrome: a bidirectional-Mendelian Randomization study. [PDF]
Front GenetBackgroundAcute Respiratory Distress Syndrome (ARDS) is a severe lung condition posing significant health risks. Observational studies have indicated a potential linkage between ARDS and various interleukins, such as Interleukin-8, −2, −6, and −1β ...
Ma JW, Tang JC, Fang HZ.
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Interleukins and cytokine biomarkers in uveitis
Indian Journal of Ophthalmology, 2020 Interleukins and cytokines are involved in the pathogenesis of uveitis of heterogeneous origin. Understanding the basics of the ocular immune privilege is a fulcrum to discern their specific role in diverse uveitis to potentially translate as therapeutic
S Balamurugan +8 more
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