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Exploring causal associations between interleukins, their receptors, and acute respiratory distress syndrome: a bidirectional-Mendelian Randomization study [PDF]
Frontiers in GeneticsBackgroundAcute Respiratory Distress Syndrome (ARDS) is a severe lung condition posing significant health risks. Observational studies have indicated a potential linkage between ARDS and various interleukins, such as Interleukin-8, −2, −6, and −1β ...
Jia-wei Ma +3 more
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The roles and clinical applications of interleukins in endometrial carcinoma
Frontiers in Oncology, 2022 As a common malignant tumor of the female reproductive system, endometrial carcinoma (EC) seriously endangers women’s health with an increasing incidence. The oncogenesis and progression of cancer are closely linked with immune microenvironment, of which
Yuqin Zang +14 more
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Challenging the Paradigm: Anti-Inflammatory Interleukins and Angiogenesis
Cells, 2022 Angiogenesis is a vital biological process, and neovascularization is essential for the development, wound repair, and perfusion of ischemic tissue. Neovascularization and inflammation are independent biological processes that are linked in response to ...
Amanda M. Peluzzo, Michael V. Autieri
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Targeting Certain Interleukins as Novel Treatment Options for Liver Fibrosis
Frontiers in Pharmacology, 2021 The liver is a major metabolic organ and an immunologically complex organ. It produces and uses many substances such as acute phase proteins, cytokines, chemokines, and complementary components to maintain the balance between immunity and tolerance ...
Su Yeon An +4 more
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Interleukin 30 to Interleukin 40 [PDF]
Journal of Interferon & Cytokine Research, 2018 Cytokines are important molecules that regulate the ontogeny and function of the immune system. They are small secreted proteins usually produced upon activation of cells of the immune system, including lymphocytes and myeloid cells. Many cytokines have been described, and several have been recognized as pivotal players in immune responses and in human
Catalan-Dibene, Jovani +2 more
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Interleukins and Ischemic Stroke
Frontiers in Immunology, 2022 Ischemic stroke after cerebral artery occlusion is one of the major causes of chronic disability worldwide. Interleukins (ILs) play a bidirectional role in ischemic stroke through information transmission, activation and regulation of immune cells ...
Hua Zhu +10 more
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Journal of Head & Neck Physicians and Surgeons, 2020 Key modulators of inflammation are interleukins (ILs). There is a complex network of interactions in acute and chronic inflammation which is modulated by ILs.
Shivani Sachdeva +3 more
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Journal of Leukocyte Biology, 1997 Abstract Interleukin 16 (IL-16) was initially described in 1982 as the first T cell chemoattractant. Through interaction with CD4, IL-16 has now been characterized as a chemoattractant for a variety of CD4+ immune cells. Recent in vivo studies have more fully characterized IL-16 as an immunom odulatory cytokine that contributes to the ...
W W, Cruikshank +2 more
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Pediatric Research, 1988 In this review we have summarized the large mass of information that has accumulated in recent years relative to the heterogeneous group of molecules known as the interleukins (IL), the lymphokines, and the cytokines that control the growth and differentiation of cells of the hematopoietic and lymphoid lineage and cells of other lineages. Our intent is
W, Strober, S P, James
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Role of interleukins in the pathogenesis of pulmonary fibrosis
Cell Death Discovery, 2021 Interleukins, a group of cytokines participating in inflammation and immune response, are proved to be involved in the formation and development of pulmonary fibrosis.
Yi Xin She, Qing Yang Yu, Xiao Xiao Tang
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