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Role of interleukins in the pathogenesis of pulmonary fibrosis
Interleukins, a group of cytokines participating in inflammation and immune response, are proved to be involved in the formation and development of pulmonary fibrosis.
Xiao Xiao Tang
exaly +2 more sources
Role of Interleukins in Type 1 and Type 2 Diabetes [PDF]
Background: Despite distinct etiologies, type 1 diabetes (T1D) and type 2 diabetes (T2D) share chronic inflammation as a core feature. Interleukins, key immune mediators, play important yet still not fully understood roles in the development and ...
Roha Asif +6 more
doaj +2 more sources
The roles and clinical applications of interleukins in endometrial carcinoma
As a common malignant tumor of the female reproductive system, endometrial carcinoma (EC) seriously endangers women’s health with an increasing incidence. The oncogenesis and progression of cancer are closely linked with immune microenvironment, of which
Yuqin Zang +14 more
doaj +1 more source
Challenging the Paradigm: Anti-Inflammatory Interleukins and Angiogenesis
Angiogenesis is a vital biological process, and neovascularization is essential for the development, wound repair, and perfusion of ischemic tissue. Neovascularization and inflammation are independent biological processes that are linked in response to ...
Amanda M. Peluzzo, Michael V. Autieri
doaj +1 more source
Targeting Certain Interleukins as Novel Treatment Options for Liver Fibrosis
The liver is a major metabolic organ and an immunologically complex organ. It produces and uses many substances such as acute phase proteins, cytokines, chemokines, and complementary components to maintain the balance between immunity and tolerance ...
Su Yeon An +4 more
doaj +1 more source
Interleukins and Ischemic Stroke
Ischemic stroke after cerebral artery occlusion is one of the major causes of chronic disability worldwide. Interleukins (ILs) play a bidirectional role in ischemic stroke through information transmission, activation and regulation of immune cells ...
Hua Zhu +10 more
doaj +1 more source
Abstract Interleukin 16 (IL-16) was initially described in 1982 as the first T cell chemoattractant. Through interaction with CD4, IL-16 has now been characterized as a chemoattractant for a variety of CD4+ immune cells. Recent in vivo studies have more fully characterized IL-16 as an immunom  odulatory cytokine that contributes to the ...
W W, Cruikshank +2 more
openaire +3 more sources
Interleukin 30 to Interleukin 40 [PDF]
Cytokines are important molecules that regulate the ontogeny and function of the immune system. They are small secreted proteins usually produced upon activation of cells of the immune system, including lymphocytes and myeloid cells. Many cytokines have been described, and several have been recognized as pivotal players in immune responses and in human
Catalan-Dibene, Jovani +2 more
openaire +4 more sources
Key modulators of inflammation are interleukins (ILs). There is a complex network of interactions in acute and chronic inflammation which is modulated by ILs.
Shivani Sachdeva +3 more
doaj +1 more source
Interleukins in Thyroid Cancer: From Basic Researches to Applications in Clinical Practice
Inflammation is crucial to tumorigenesis and progression of many cancers. Inflammatory molecules in tumor microenvironment exert pro- or anti-tumor effects.
Chuang Xi +8 more
doaj +1 more source

