Results 151 to 160 of about 178,368 (223)

Special Issue "Nephrotic Syndrome: Pathomechanism, Diagnostics, and Novel Treatment Options". [PDF]

Biomedicines
Katayama K, Saiki R, Dohi K.
europepmc   +1 more source

Effect of cyclosporin A and dexamethasone on interleukin 2 receptor gene expression. [PDF]

, 1986
John C. Reed, Ammaar H. Abidi, James D. Alpers, R G Hoover, R J Robb, Peter C. Nowell̀   +5 more
openalex   +1 more source

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization

Advanced Science, EarlyView.
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan, Donghui Chen, Shuangna Zhang, Chaofan Li, Qingyun Fang, Dinghua Chen, Jiabao Liu, Xin Jiang, Yingjie Zhang, Wanjun Shen, Guangyan Cai, Xiangmei Chen, Ping Li   +12 more
wiley   +1 more source

Room temperature quantitative liquid concentration device and application to interleukins analysis in a B-cell culture medium. [PDF]

Anal Sci
Kawanabe R, Tazawa H, Mawatari K, Yoshizaki A.   +3 more
europepmc   +1 more source

Analysis in serum-free culture of the targets of recombinant human hemopoietic growth factors: interleukin 3 and granulocyte/macrophage-colony-stimulating factor are specific for early developmental stages.

, 1988
Yoshiaki Sonoda, Y C Yang, GG Wong, S C Clark, Megumu Ogawa   +4 more
openalex   +1 more source

Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells. [PDF]

, 1986
Ulrich Siebenlist, Delphine Durand, Peter Bressler, Nikki J. Holbrook, Chad Norris, Malek Kamoun, J A Kant, Gerald R. Crabtree   +7 more
openalex   +1 more source

TRIM25‐Mediated INSIG1 Ubiquitination Promotes MASH Progression Through Reprogramming Lipid Metabolism

Advanced Science, EarlyView.
TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang, Xiangxu Kong, Wei Wang, Huaxin Zhou, Haoran Qu, Zhengyao Guan, Honglei Wu, Xiangyu Zhai, Bin Jin   +8 more
wiley   +1 more source

An Attomolar-Level Optical Device for Monitoring Receptor-Analyte Interactions Without Functionalization Steps: A Case Study of Cytokine Detection. [PDF]

Sensors (Basel)
Cennamo N, Arcadio F, Marzano C, Pitruzzella R, Seggio M, Pesavento M, Toldo S, Abbate A, Zeni L.   +8 more
europepmc   +1 more source

Regulation of interleukin 1 gene expression by adherence and lipopolysaccharide. [PDF]

, 1987
Robert C. Fuhlbrigge, David Chaplin, Jeanne-Marie Kíely, Emil R. Unanue   +3 more
openalex   +1 more source

Autophagy Related 5 Promotes Mitochondrial Fission and Inflammation via HSP90‐HIF‐1α‐Mediated Glycolysis in Kidney Fibrosis

Advanced Science, EarlyView.
When the normal kidney is subjected to injurious stimuli, it can lead to persistent activation of ATG5. The activation of ATG5 promotes HSP90‐HIF‐1α interaction, resulting in stabilization of HIF‐1α and subsequent activation of glycolysis. Consequently, this process contributes to mitochondrial fission and inflammation, ultimately culminating in kidney
Yan Hu, Jinqing Li, Hui Chen, Yingfeng Shi, Xiaoyan Ma, Yi Wang, Xialin Li, Qin Zhong, Yishu Wang, Daofang Jiang, Shougang Zhuang, Na Liu   +11 more
wiley   +1 more source