Results 31 to 40 of about 1,444,628 (322)
Intermediate filament dynamics: What we can see now and why it matters
Bioessays, 2016 The mechanical properties of vertebrate cells are largely defined by the system of intermediate filaments (IF). As part of a dense network, IF polymers are constantly rearranged and relocalized in the cell to fulfill their duty as cells change shape ...
A. Robert, C. Hookway, Vladimir Gelfand
semanticscholar +1 more source
Lens intermediate filaments [PDF]
Experimental Eye Research, 2009 The ocular lens assembles two separate intermediate filament systems sequentially with differentiation. Canonical 8-11 nm IFs composed of Vimentin are assembled in lens epithelial cells and younger fiber cells, while the fiber cell-specific beaded filaments are switched on as fiber cell elongation initiates.
openaire +2 more sources
Role of Intermediate Filaments in Vesicular Traffic
Cells, 2016 Intermediate filaments are an important component of the cellular cytoskeleton. The first established role attributed to intermediate filaments was the mechanical support to cells.
Azzurra Margiotta, Cecilia Bucci
doaj +1 more source
Neuronal intermediate filament IgGs in CSF: Autoimmune Axonopathy Biomarkers
Annals of Clinical and Translational Neurology, 2021 Objectives To describe CSF‐defined neuronal intermediate filament (NIF) autoimmunity. Methods NIF‐IgG CSF‐positive patients (41, 0.03% of 118599 tested, 1996–2019) were included (serum was neither sensitive nor specific).
Andrew McKeon +11 more
doaj +1 more source
Novel origin of lamin-derived cytoplasmic intermediate filaments in tardigrades
eLife, 2016 Intermediate filament (IF) proteins, including nuclear lamins and cytoplasmic IF proteins, are essential cytoskeletal components of bilaterian cells. Despite their important role in protecting tissues against mechanical force, no cytoplasmic IF proteins ...
Lars Hering +4 more
doaj +1 more source
Epithelial Intermediate Filaments: Guardians against Microbial Infection?
Cells, 2016 Intermediate filaments are abundant cytoskeletal components of epithelial tissues. They have been implicated in overall stress protection. A hitherto poorly investigated area of research is the function of intermediate filaments as a barrier to microbial
Florian Geisler, Rudolf E. Leube
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Structure of the Intermediate Filament-Binding Region of Desmoplakin. [PDF]
PLoS ONE, 2016 Desmoplakin (DP) is a cytoskeletal linker protein that connects the desmosomal cadherin/plakoglobin/plakophilin complex to intermediate filaments (IFs).
Hyunook Kang +4 more
doaj +1 more source
Plectin–intermediate filament partnership in skin, skeletal muscle, and peripheral nerve
Histochemistry and Cell Biology, 2013 Plectin is a large, 500-kDa, intermediate filament (IF)-associated protein. It acts as a cytoskeletal crosslinker and signaling scaffold, affecting mechanical as well as dynamic properties of the cytoskeleton.
M. J. Castañón +3 more
semanticscholar +1 more source
Molecular evolution of type VI intermediate filament proteins
BMC Evolutionary Biology, 2007 Background Tanabin, transitin and nestin are type VI intermediate filament (IF) proteins that are developmentally regulated in frogs, birds and mammals, respectively.
Vincent Michel +3 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source