Results 51 to 60 of about 942,341 (290)

Lens intermediate filaments [PDF]

Experimental Eye Research, 2009
The ocular lens assembles two separate intermediate filament systems sequentially with differentiation. Canonical 8-11 nm IFs composed of Vimentin are assembled in lens epithelial cells and younger fiber cells, while the fiber cell-specific beaded filaments are switched on as fiber cell elongation initiates.
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Intermediate filament protein partnership in astrocytes

, 1999
Intermediate filaments are general constituents of the cytoskeleton. The function of these structures and the requirement for different types of intermediate filament proteins by individual cells are only partly understood.
Celis, J.E., Berthold, C.-H., Betsholtz, C., Betsholtz, C, Berthold, C-H, Eliasson, C, Stakeberg, J., Pekny, M., Stakeberg, J, Celis, JE, Sahlgren, C., Pekny, M, Eliasson, C., Sahlgren, CM Cecilia   +13 more
core   +1 more source

Re-expression of the intermediate filament nestin in reactive astrocytes

Neurobiology of Disease, 1995
The intermediate filament nestin is highly expressed in multipotential stem cells of the developing central nervous system (CNS). During neuro- and gliogenesis, nestin is replaced by cell type-specific intermediate filaments, e.g.
R.C.S. Lin, D.F. Matesic, M. Marvin, R.D.G. McKay, O. Brüstle   +4 more
doaj   +1 more source

Diamond Films on Stainless Steel Substrates with an Interlayer Applied by Laser Cladding [PDF]

Materials Research, 2017
The objective of this work is the Hot Filament Chemical Vapor Deposition (HFCVD) of diamond films on stainless steel substrates using a new technique for intermediate barrier forming, made by laser cladding process.
Andre Contin, Kenya Aparecida Alves, Raonei Alves Campos, Getúlio de Vasconcelos, Djoille Denner Damm, Vladimir Jesus Trava-Airoldi, Evaldo José Corat   +6 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Reconstitution of cytolinker-mediated crosstalk between actin and vimentin

European Journal of Cell Biology
Cell shape and motility are determined by the cytoskeleton, an interpenetrating network of actin filaments, microtubules, and intermediate filaments. The biophysical properties of each filament type individually have been studied extensively by cell-free
Irene Istúriz Petitjean, Quang D. Tran, Angeliki Goutou, Zima Kabir, Gerhard Wiche, Cécile Leduc, Gijsje H. Koenderink   +6 more
doaj   +1 more source

Withaferin a alters intermediate filament organization, cell shape and behavior. [PDF]

PLoS ONE, 2012
Withaferin A (WFA) is a steroidal lactone present in Withania somnifera which has been shown in vitro to bind to the intermediate filament protein, vimentin. Based upon its affinity for vimentin, it has been proposed that WFA can be used as an anti-tumor
Boris Grin, Saleemulla Mahammad, Tatjana Wedig, Megan M Cleland, Lester Tsai, Harald Herrmann, Robert D Goldman   +6 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source