Results 91 to 100 of about 104,417 (205)
The mechanical response of semiflexible networks to localized perturbations
Previous research on semiflexible polymers including cytoskeletal networks in cells has suggested the existence of distinct regimes of elastic response, in which the strain field is either uniform (affine) or non-uniform (non-affine) under external ...
A. J. Levine +7 more
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Biomechanical response of skeletal muscle to eccentric contractions
The forced lengthening of an activated skeletal muscle has been termed an eccentric contraction (EC). This review highlights the mechanically unique nature of the EC and focuses on the specific disruption of proteins within the cell known as cytoskeletal
Richard L. Lieber
doaj +1 more source
Unfolding cross-linkers as rheology regulators in F-actin networks
We report on the nonlinear mechanical properties of a statistically homogeneous, isotropic semiflexible network cross-linked by polymers containing numerous small unfolding domains, such as the ubiquitous F-actin cross-linker Filamin.
Alex J. Levine +10 more
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Anomalous fluctuations of active polar filaments
Using a simple model, we study the fluctuating dynamics of inextensible, semiflexible polar filaments interacting with active and directed force generating centres such as molecular motors.
C. Viegel +22 more
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The distribution of intermediate-filament (IF) proteins of the keratin, vimentin and desmin type in breast stromal sarcomas, carcinosarcomas, metaplastic carcinomas and phyllodes tumors has been compared using the avidin-biotin complex immunoperoxidase ...
Donatella Santini +6 more
doaj +1 more source
Transverse fluctuations of grafted polymers
We study the statistical mechanics of grafted polymers of arbitrary stiffness in a two-dimensional embedding space with Monte Carlo simulations. The probability distribution function of the free end is found to be highly anisotropic and non-Gaussian for ...
A. Ott +19 more
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Defects in Crystalline Packings of Twisted Filament Bundles: II. Dislocations and Grain Boundaries
Twisted and rope-like assemblies of filamentous molecules are common and vital structural elements in cells and tissue of living organisms. We study the intrinsic frustration occurring in these materials between the two-dimensional organization of ...
Amir Azadi +9 more
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The present review describes recent research on the regulation by glutamate and Ca2+ of the phosphorylation state of the intermediate filament protein of the astrocytic cytoskeleton, glial fibrillary acidic protein (GFAP), in immature hippocampal slices.
Rodnight R. +3 more
doaj
Molecular motors: design, mechanism and control
Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which synthesize ...
Chowdhury, Debashish
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Effects of keratin filaments on ERK signaling during Fas-induced death of cervical cancer (HeLa) cells [PDF]
Survival of cancer cells is influenced by a variety of factors, including physical elements such as keratin filaments. We know HeLa cells containing or lacking keratin 8/18 intermediate filaments (K+ and K- cells, respectively) are more sensitive to the ...
Berger, Amanda
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