Results 91 to 100 of about 104,417 (205)

The mechanical response of semiflexible networks to localized perturbations

open access: yes, 2005
Previous research on semiflexible polymers including cytoskeletal networks in cells has suggested the existence of distinct regimes of elastic response, in which the strain field is either uniform (affine) or non-uniform (non-affine) under external ...
A. J. Levine   +7 more
core   +2 more sources

Biomechanical response of skeletal muscle to eccentric contractions

open access: yesJournal of Sport and Health Science, 2018
The forced lengthening of an activated skeletal muscle has been termed an eccentric contraction (EC). This review highlights the mechanically unique nature of the EC and focuses on the specific disruption of proteins within the cell known as cytoskeletal
Richard L. Lieber
doaj   +1 more source

Unfolding cross-linkers as rheology regulators in F-actin networks

open access: yes, 2007
We report on the nonlinear mechanical properties of a statistically homogeneous, isotropic semiflexible network cross-linked by polymers containing numerous small unfolding domains, such as the ubiquitous F-actin cross-linker Filamin.
Alex J. Levine   +10 more
core   +1 more source

Anomalous fluctuations of active polar filaments

open access: yes, 2002
Using a simple model, we study the fluctuating dynamics of inextensible, semiflexible polar filaments interacting with active and directed force generating centres such as molecular motors.
C. Viegel   +22 more
core   +1 more source

Intermediate-sized Filament Proteins (Keratin, Vimentin, Desmin) in Metaplastic Carcinomas, Carcinosarcomas and Stromal Sarcomas of the Breast

open access: yesThe International Journal of Biological Markers, 1987
The distribution of intermediate-filament (IF) proteins of the keratin, vimentin and desmin type in breast stromal sarcomas, carcinosarcomas, metaplastic carcinomas and phyllodes tumors has been compared using the avidin-biotin complex immunoperoxidase ...
Donatella Santini   +6 more
doaj   +1 more source

Transverse fluctuations of grafted polymers

open access: yes, 2003
We study the statistical mechanics of grafted polymers of arbitrary stiffness in a two-dimensional embedding space with Monte Carlo simulations. The probability distribution function of the free end is found to be highly anisotropic and non-Gaussian for ...
A. Ott   +19 more
core   +1 more source

Defects in Crystalline Packings of Twisted Filament Bundles: II. Dislocations and Grain Boundaries

open access: yes, 2011
Twisted and rope-like assemblies of filamentous molecules are common and vital structural elements in cells and tissue of living organisms. We study the intrinsic frustration occurring in these materials between the two-dimensional organization of ...
Amir Azadi   +9 more
core   +1 more source

Control of the phosphorylation of the astrocyte marker glial fibrillary acidic protein (GFAP) in the immature rat hippocampus by glutamate and calcium ions: possible key factor in astrocytic plasticity

open access: yesBrazilian Journal of Medical and Biological Research, 1997
The present review describes recent research on the regulation by glutamate and Ca2+ of the phosphorylation state of the intermediate filament protein of the astrocytic cytoskeleton, glial fibrillary acidic protein (GFAP), in immature hippocampal slices.
Rodnight R.   +3 more
doaj  

Molecular motors: design, mechanism and control

open access: yes, 2008
Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which synthesize ...
Chowdhury, Debashish
core   +1 more source

Effects of keratin filaments on ERK signaling during Fas-induced death of cervical cancer (HeLa) cells [PDF]

open access: yes, 2014
Survival of cancer cells is influenced by a variety of factors, including physical elements such as keratin filaments. We know HeLa cells containing or lacking keratin 8/18 intermediate filaments (K+ and K- cells, respectively) are more sensitive to the ...
Berger, Amanda
core   +1 more source

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