Results 81 to 90 of about 948,768 (269)
Frontiers in ImmunologyBackgroundAging is a major contributor to chronic inflammation and coronary artery disease (CAD), yet how age influences monocyte chemokine receptor expression in relation to disease severity remains incompletely defined.Methods and resultsWe performed ...
Ravi K. Komaravolu +19 more
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CTRP3 induces an intermediate switch of CD14++CD16+ monocyte subset with anti‑inflammatory phenotype
Experimental and Therapeutic Medicine, 2020 Acute myocardial infarction (AMI) evokes a temporally coordinated immune response, in which monocytes are critically involved in the clearance of cell debris; however, excessive inflammation induced by the classical sub-population of monocytes frequently limits the endogenous reparative process.
Zhu, Hongtao +9 more
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FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Towards a refined definition of monocyte subsets
Frontiers in Immunology, 2013 In a nomenclature proposal published in 2010 monocytes were subdivided into classical and nonclassical cells and in addition an intermediate monocyte subset was proposed.
Loems eZiegler-Heitbrock +1 more
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Acta Dermato-Venereologica, 2021 Uraemic pruritus is one of the most bothersome symptoms in patients receiving haemodialysis. A total of 175 patients receiving maintenance haemodialysis, with 74 patients experiencing uraemic pruritus, were prospectively recruited to assess the influence
Mei-Ju Ko +7 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
Intermediate monocytes are significantly elevated in CRC patients.
, 2012 Monocyte subpopulations were determined by flow cytometry and are given in % of total leukocyte counts in healthy individuals, patients with localized CRC and patients with mCRC.
Christine Brostjan (137496) +10 more
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Frontiers in Psychiatry, 2019 Introduction: Major depressive disorder (MDD) patients experience a systemic inflammatory stage. Monocytes play an important role in innate inflammatory responses and may be modulated by bacterial translocation.
Miguel Angel Alvarez-Mon +23 more
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Clinical and Experimental Immunology, 2016 SummaryMicroarray of peripheral blood (PB) and synovial fluid mononuclear cells (PBMC, SFMC) of patients with juvenile idiopathic arthritis–enthesitis-related arthritis (JIA-ERA) has shown the involvement of monocytes. On the basis of CD14 and CD16 expression, monocytes are classified as classical, intermediate and non-classical.
P, Gaur, A, Myles, R, Misra, A, Aggarwal
openaire +3 more sources