Results 91 to 100 of about 521,909 (335)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
An Extension Failure Criterion for Brittle Rock
Advances in Civil Engineering, 2020 Under the triaxial compressive state, the compressive strain is supposed to happen in the direction of the maximum principal stress, but tensile strain happens in the direction of the minimum principal stress.
Aizhong Lu, Ning Zhang, Guisen Zeng
doaj +1 more source
Analysis of temperature effects near mode I cracks in glassy polymers [PDF]
, 2005 A previous isothermal study has shown that the toughness of glassy polymers is governed by the competition between shear yielding and crazing. The present work aims at investigating loading rates for which thermal effects need to be accounted for.
Basu, S., +2 more
core +5 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Influence Of Intermediate Principal Stress On Solution Of Planar Stability Problems
, 2015 {"references": ["P. V. Lade \"Assessment of test data for selection of 3-D failure criterion for sand.\" Int. J. Numer. Anal. Meth. Geomech, 2006; 30:307\u2013333.", "R. O. Davis and A. P. S. Selvadurai, Plasticity and Geomechanics. Cambridge University Press, 2002, 287 p.", "H.
M. Jahanandish, M. B. Zeydabadinejad
openaire +1 more source
Intermediate Principal Stress Dependency in Strength of Transversely Isotropic Mohr-Coulomb Rock [PDF]
Journal of Korean Society For Rock Mechanics, 2013 A number of true triaxial tests on rock samples have been conducted since the late 1960 and their results strongly suggest that the intermediate principal stress has a considerable effect on rock strength. Based on these experimental evidence, various 3-D rock failure criteria accounting for the effect of the intermediate principal stress have been ...
openaire +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Geomechanics and Geophysics for Geo-Energy and Geo-ResourcesThe study of sandstone dilation characteristics under actual mining and excavation conditions promotes the safe and efficient development of underground engineering.
Wenpu Li +6 more
doaj +1 more source
Transient stress evolution in repulsion and attraction dominated glasses
, 2014 We present results from microscopic mode coupling theory generalized to colloidal dispersions under shear in an integration-through-transients formalism.
Amann, Christian P., Fuchs, Matthias
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source