Results 71 to 80 of about 421,581 (294)

Restructuring of colloidal aggregates in shear flow: Coupling interparticle contact models with Stokesian dynamics

open access: yes, 2012
A method to couple interparticle contact models with Stokesian dynamics (SD) is introduced to simulate colloidal aggregates under flow conditions.
A.A. Potanin   +47 more
core   +1 more source

Unified anisotropic elastoplastic model for sand [PDF]

open access: yes, 2016
This paper presents a unified approach to model the influence of fabric anisotropy and its evolution on both the elastic and plastic responses of sand.
Gao, Zhiwei, Zhao, Jidong
core   +4 more sources

Relationship Between the Orientation of Maximum Permeability and Intermediate Principal Stress in Fractured Rocks [PDF]

open access: yesWater Resources Research, 2018
AbstractFlow and transport properties of fractured rock masses are a function of geometrical structures across many scales. These structures result from physical processes and states and are highly anisotropic in nature. Fracture surfaces often tend to be shifted with respect to each other, which is generally a result of stress‐induced displacements ...
Philipp S. Lang   +3 more
openaire   +4 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Experimental study on mechanical properties of fissured loess under true triaxial conditions

open access: yesScientific Reports
Fissured loess is one of the important factors that cause geological disasters in the Loess Plateau. This paper analyzes the mechanical characteristics of fissured loess under different confining pressures and different intermediate effective principal ...
Jielong Sun   +5 more
doaj   +1 more source

Unified solution of Meyerhof’s ultimate bearing capacity for strip foundation resting on unsaturated soils

open access: yesYantu gongcheng xuebao, 2018
Based on the unified solution of shear strength for unsaturated soils, a unified solution of Meyerhof’s ultimate bearing capacity for strip foundation is obtained by considering the effects of intermediate principal stress, matric suction and strength ...
ZHANG Chang-guang 1,2, YAN Qing 1, WU Li-zhou 2, CAO Xue-ye 1, ZHANG Cheng-lin 1
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

IMP Science Gateway: from the Portal to the Hub of Virtual Experimental Labs in Materials Science

open access: yes, 2014
"Science gateway" (SG) ideology means a user-friendly intuitive interface between scientists (or scientific communities) and different software components + various distributed computing infrastructures (DCIs) (like grids, clouds, clusters), where ...
Baskova, Olexandra   +5 more
core   +1 more source

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