Results 61 to 70 of about 521,909 (335)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Mechanical characteristics of plane strain unloading conditions with different initial states

Yantu gongcheng xuebao
For the plane strain unloading issues in loess engineering, the lateral unloading plain strain tests on the loess with various initial states (intact, remolded and saturated) under different confining pressures and water contents are carried out by using
ZHANG Yu 1, 2, ZHAO Yang 1, LIU Keji 1, YE Sheng 1, LIU Jin 1, 2, DING Xiao 1, ZHANG Meng 1, QU Yonglong 1
doaj   +1 more source

Irritable Bowel Syndrome patients exhibit depressive and anxiety scores in the subsyndromal range [PDF]

, 2008
Irritable bowel syndrome (IBS) patients frequently experience affective disorders and psychiatric outpatients frequently meet criteria for IBS. The exact nature of this co-morbidity is not clear. 34 patients with Rome-II diagnosed IBS were recruited from
Hendry, Julie, Hince, Dana A, Hood, Sean D, Potokar, John, Probert, Chris S J, Rich, Ann S, Shufflebotham, Jonathon Q   +6 more
core   +2 more sources

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

A Stress-Dilatancy Relationship for Rockfill Incorporating Particle Breakage and Intermediate Principal-Stress Ratio

KSCE Journal of Civil Engineering, 2019
Rockfill material is widely used for construction of high rockfill dam, which undergoes significant particle breakage and three-dimensional stress path induced by the water pressure, earthquake, etc. The dilatancy equation, defined as the function of the dilatancy dg and the stress ratio η, is regarded as the foundation of elastoplastic constitutive ...
Wanli Guo, Li Chen
openaire   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Effect of large particle content on strength and failure mode of binary granular mixture in shear under plane strain condition [PDF]

E3S Web of Conferences
The strength and failure modes of binary granular mixture composed of two different sized particles, such as gravel and sand, vary depending on the content of gravel (large particle content).
Taue Masato, Nakata Yukio, Kajiyama Shintaro   +2 more
doaj   +1 more source

Unloading Mechanics and Energy Characteristics of Sandstone under Different Intermediate Principal Stress Conditions

Advances in Civil Engineering, 2021
The TRW-3000 true triaxial rock testing machine was used to conduct loading and unloading tests of sandstone under different σ2, and the true triaxial lateral unloading mechanics and energy characteristics of sandstone under different σ2 were studied ...
Yingjie Zhang, Jiangteng Li, Gang Ma, Shuangfei Liu   +3 more
doaj   +1 more source

Evaluation of the surface strength of glass plates shaped by hot slumping process

, 2014
The Hot Slumping Technology is under development by several research groups in the world for the realization of grazing-incidence segmented mirrors for X-ray astronomy, based on thin glass plates shaped over a mould at temperatures above the ...
Basso, S., Bavdaz, M., Borsa, F., Citterio, O., Civitani, M., D'Este, A., Dall'Igna, R., Ghigo, M., Martelli, F., Pareschi, G., Parodi, G., Proserpio, L., Salmaso, B., Silvestri, M., Sironi, G., Spiga, D., Tagliaferri, G., Wille, E.   +17 more
core   +1 more source