Results 91 to 100 of about 17,595 (163)

Heart rate, blood pressure, and SpO2 responses to simulated 5000 m hypobaric exposure in healthy male Vietnamese pilots

Physiological Reports, Volume 14, Issue 3, February 2026.
Abstract This study was motivated by the limited high‐altitude physiology data available for Asian military aviators, especially in Vietnam. To characterize acute heart rate (HR), blood pressure (BP), and oxygen saturation (SpO2) responses in healthy Vietnamese pilots during simulated 5000 m hypobaric exposure. Seventy‐five healthy male military pilots
Xuan Nguyen Thanh, Phong Nguyen Hong, Tuan Tran Ngoc, Phuong Nguyen Minh, Toan Pham Quoc, Toan Nguyen Duy, Thao Pham Ngoc, Thong Nguyen Huy, Luyen Nguyen Van, Thuc Luong Cong   +9 more
wiley   +1 more source

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

British Journal of Clinical Pharmacology, Volume 92, Issue 1, Page 58-72, January 2026.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post, Cayla Denney, Adam Cohen, Jens Jordan, Ulrich Limper   +4 more
wiley   +1 more source

The features of the nitric oxide system in the left ventricle myocardium in the rats with experimental intermittent hypoxia of different duration

Patologìâ, 2019
The aim was to determine the features of the NO system status in the left ventricular myocardium in the rats with intermittent hypoxic hypobaric hypoxia during 15 and 60 days. Material and methods.
Yu. M. Kolesnyk, M. I. Isachenko, O. V. Melnikova   +2 more
doaj   +1 more source

Long-term chronic intermittent hypoxia: a particular form of chronic high-altitude pulmonary hypertension

Pulmonary Circulation, 2020
In some subjects, high-altitude hypobaric hypoxia leads to high-altitude pulmonary hypertension. The threshold for the diagnosis of high-altitude pulmonary hypertension is a mean pulmonary artery pressure of 30 mmHg, even though for general pulmonary ...
Julio Brito, Patricia Siques, Eduardo Pena   +2 more
doaj   +1 more source

Myocardial interstitial matrix as novel target for succinic acid treatment strategies during experimental hypobaric hypoxia

Russian Open Medical Journal, 2019
Objective — Quantitative morphological studies of myocardial cellular elements. Aim of research is to study myocardial interstitial matrix with and without succinic acid treatment in the rats exposed to intermittent hypobaric hypoxia.
Igor V. Zadnipryany, Tatiana P. Sataieva, Olga S. Tretiakova, Walery Zukow   +3 more
doaj   +1 more source

Effect of intermittent hypobaric hypoxia on efficacy & clearance of drugs.

The Indian journal of medical research, 2012
People travelling to high altitude for occupational, recreational or religious purposes are mostly healthy and fit but sometimes they use drugs for common ailments like influenza, acute mountain sickness or chronic disease like diabetes. Limitation of oxygen at high altitude may compromise metabolism of drugs.
Anjana G, Vij, Krishna, Kishore, Joginder, Dey   +2 more
openaire   +1 more source

Role of intermittent hypoxic training combined with methazolamide in the prevention of high-altitude cerebral edema in rats

Scientific Reports
Although intermittent hypoxia training (IHT) and methazolamide (MTZ) alone can prevent high-altitude cerebral edema (HACE) to varying degrees, their efficacy and dispersion remain limited. However, only a handful of trials have explored the effectiveness
Weicheng Peng, Haiyang Ma, Rui Zhao, Sheng Xu, Meng Lv, Bei Jing, Zhiqiang Hu   +6 more
doaj   +1 more source

The Use of Hypoxic Therapy for the Treatment of Epilepsy

Archive of Clinical Medicine
Epilepsy is one of the most common and dangerous diseases in the world. The complexity of the etiology of this disease leads, in many cases, to the ineffectiveness of treatment protocols.
Oleksandr Kiian
doaj   +1 more source

The effects of acute intermittent hypoxia on cardiovascular parameters in normotensive and chronic hypobaric hypoxia-induced hypertensive rabbits

General physiology and biophysics, 2014
The effects of both chronic hypoxia and acute intermittent hypoxia (AIH) on cardiovascular system are unclear. We designed this study to develop a rabbit model of hypertension by exposure to chronic hypobaric hypoxia (CHH) and to investigate the effects of AIH on hypertensive rabbits.
Yaman, Muhittin O., Guner, Ibrahim, Uzun, Hafize, Sahin, Gulderen, Yelmen, Nermin   +4 more
openaire   +3 more sources

Effects of chronic intermittent hypobaric hypoxia on expression and promoter region methylation of key enzyme genes related to glucose metabolism in diabetic mice

环境与职业医学
BackgroundChronic intermittent hypobaric hypoxia (CIHH) can effectively alleviate type 2 diabetes mellitus (T2DM). In this process, the underlying mechanism in its association with the epigenetic regulation of DNA methylation in the promoter regions of ...
Chunhong SUI, Yantao HE, Yawei XU, Pengyan JI, Ying CHANG, Dongfang ZHANG, Donghai ZHAO, Lianhai JIN, Cheng WANG   +8 more
doaj   +1 more source