Results 1 to 10 of about 37,990 (119)

Chronic Intermittent Hypoxia Increases Cell Proliferation in Hepatocellular Carcinoma

open access: yesCells, 2022
Obstructive sleep apnea (OSA) syndrome is characterized by chronic intermittent hypoxia and is associated with an increased risk of all-cause mortality, including cancer mortality.
Lydie Carreres   +11 more
doaj   +1 more source

Role of raphe magnus 5-HT1A receptor in increased ventilatory responses induced by intermittent hypoxia in rats

open access: yesRespiratory Research, 2022
Background Intermittent hypoxia induces increased ventilatory responses in a 5-HT-dependent manner. This study aimed to explore that effect of raphe magnus serotonin 1A receptor (5-HT1A) receptor on the increased ventilatory responses induced by ...
Jiao Su   +8 more
doaj   +1 more source

Pentobarbital Anesthesia Suppresses the Glucose Response to Acute Intermittent Hypoxia in Rat

open access: yesFrontiers in Physiology, 2021
A key feature of sleep disordered breathing syndromes, such as obstructive sleep apnea is intermittent hypoxia. Intermittent hypoxia is well accepted to drive the sympathoexcitation that is frequently associated with hypertension and diabetes, with ...
Polina E. Nedoboy   +5 more
doaj   +1 more source

The interplay between prior selection, mild intermittent exposure, and acute severe exposure in phenotypic and transcriptional response to hypoxia

open access: yesEcology and Evolution, 2022
Hypoxia has profound and diverse effects on aerobic organisms, disrupting oxidative phosphorylation and activating several protective pathways. Predictions have been made that exposure to mild intermittent hypoxia may be protective against more severe ...
Millicent N. Ekwudo   +3 more
doaj   +1 more source

Sodium Tanshinone IIA Sulfonate Attenuates Tumor Oxidative Stress and Promotes Apoptosis in an Intermittent Hypoxia Mouse Model

open access: yesTechnology in Cancer Research & Treatment, 2020
Objective: Intermittent hypoxia, a significant feature of obstructive sleep apnea, has pro-tumorigenic effects. Here, we investigated the effect of sodium tanshinone IIA sulfonate on oxidative stress and apoptosis in a mouse model of Lewis lung carcinoma
Xiao-Bin Zhang PhD   +7 more
doaj   +1 more source

Acute intermittent hypoxia drives hepatic de novo lipogenesis in humans and rodents

open access: yesMetabolism Open, 2022
Background and aims: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver condition. It is tightly associated with an adverse metabolic phenotype (including obesity and type 2 diabetes) as well as with obstructive sleep apnoea (OSA)
Jonathan M. Hazlehurst   +16 more
doaj   +1 more source

Microglial exosomes alleviate intermittent hypoxia-induced cognitive deficits by suppressing NLRP3 inflammasome

open access: yesBiology Direct, 2023
Intermittent hypoxia is the best predictor of developing cognitive decline and Alzheimer’s disease progression in patients with obstructive sleep apnea.
Yaodan Zhang   +7 more
doaj   +1 more source

Experimental study of the pattern of genes activated by multi-day intermittent hypoxia in the rat pancreas

open access: yesPatologìâ, 2023
Intermittent hypoxia affects a variety of pathological conditions in the body and is used in medicine to reproduce the sanogenic therapeutic effect.
T. V. Ivanenko   +2 more
doaj   +1 more source

Association Between Intermittent Hypoxia and Left Ventricular Remodeling in Patients With Obstructive Sleep Apnea-Hypopnea Syndrome

open access: yesFrontiers in Physiology, 2021
The present study was undertaken to examine the association between intermittent hypoxia and left ventricular (LV) remodeling and explore which parameter of intermittent hypoxia is most relevant to LV remodeling in patients with obstructive sleep apnea ...
Ming Deng   +7 more
doaj   +1 more source

Altered production of reproductive neuropeptides in rats subjected to chronic intermittent hypoxia [PDF]

open access: yesJournal of Integrative Neuroscience, 2021
Hypobaric hypoxia is a stressful condition known to decrease fertility both in humans and animals. However, the mechanism by which the hypothalamus-pituitary-gonad axis is altered remains unknown.
Antonela Romina Terrizzi   +2 more
doaj   +1 more source

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