Results 21 to 30 of about 38,089 (218)

Intermittent hypoxia in childhood: the harmful consequences versus potential benefits of therapeutic uses

Frontiers in Pediatrics, 2015
Intermittent hypoxia often occurs in early infancy in both preterm and term infants and especially at 36 to 44 weeks postmenstrual age. These episodes of intermittent hypoxia could result from sleep-disordered breathing or may be temporally unrelated to ...
Tatiana V. Serebrovskaya, Lei eXi
doaj   +1 more source

Endurance exercise under short‐duration intermittent hypoxia promotes endurance performance via improving muscle metabolic properties in mice

Physiological Reports, 2022
This study was designed to (1) investigate the effects of acute exercise under intermittent hypoxia on muscle mRNA and protein levels, and (2) clarify the mechanisms by which exercise under intermittent hypoxia improves endurance capacity.
Junichi Suzuki
doaj   +1 more source

Fast cycling of intermittent hypoxia in a physiomimetic 3D environment: A novel tool for the study of the parenchymal effects of sleep apnea

Frontiers in Pharmacology, 2023
Background: Patients with obstructive sleep apnea (OSA) experience recurrent hypoxemic events with a frequency sometimes exceeding 60 events/h. These episodic events induce downstream transient hypoxia in the parenchymal tissue of all organs, thereby ...
Alicia Jurado, Anna Ulldemolins, Helena Lluís, Helena Lluís, Xavier Gasull, Xavier Gasull, Núria Gavara, Núria Gavara, Raimon Sunyer, Raimon Sunyer, Jorge Otero, Jorge Otero, Jorge Otero, David Gozal, Isaac Almendros, Isaac Almendros, Isaac Almendros, Ramon Farré, Ramon Farré, Ramon Farré   +19 more
doaj   +1 more source

Intermittent hypoxia regulates stem-like characteristics and differentiation of neuroblastoma cells.

PLoS ONE, 2012
BackgroundNeuroblastomas are the most common extracranial solid tumors in children. Neuroblastomas are derived from immature cells of the sympathetic nervous system and are characterized by clinical and biological heterogeneity.
Vasantha Kumar Bhaskara, Indra Mohanam, Jasti S Rao, Sanjeeva Mohanam   +3 more
doaj   +1 more source

Melatonin prevents hyperglycemia in a model of sleep apnea

Archives of Endocrinology and Metabolism
Objective Obstructive sleep apnea is a common disorder associated with aging and obesity. Apneas cause repeated arousals, intermittent hypoxia, and oxidative stress.
Renata Schenkel Rivera Kaminski, Denis Martinez, Micheli Fagundes, Emerson Ferreira Martins, Carolina Caruccio Montanari, Darlan Pase Rosa, Cintia Zappe Fiori, Norma Possa Marroni   +7 more
doaj   +1 more source

Physiological and Biological Responses to Short-Term Intermittent Hypobaric Hypoxia Exposure: From Sports and Mountain Medicine to New Biomedical Applications

Frontiers in Physiology, 2018
In recent years, the altitude acclimatization responses elicited by short-term intermittent exposure to hypoxia have been subject to renewed attention. The main goal of short-term intermittent hypobaric hypoxia exposure programs was originally to improve
Ginés Viscor, Joan R. Torrella, Luisa Corral, Antoni Ricart, Casimiro Javierre, Teresa Pages, Josep L. Ventura   +6 more
doaj   +1 more source

Increased C-C chemokine receptor 2 gene expression in monocytes of severe obstructive sleep apnea patients and under intermittent hypoxia. [PDF]

PLoS ONE, 2014
Obstructive sleep apnea (OSA) is known to be a risk factor of coronary artery disease. The chemotaxis and adhesion of monocytes to the endothelium in the early atherosclerosis is important.
Li-Pang Chuang, Ning-Hung Chen, Shih-Wei Lin, Ying-Ling Chang, Hsiang-Ruei Liao, Yu-Sheng Lin, I-Ju Chao, Yuling Lin, Jong-Hwei S Pang   +8 more
doaj   +1 more source

Bubble Formation Control: Fabrication of Centimeter‐Sized Tissue‐Like Constructs by Catalase‐Coated Oxygen‐Releasing Hydrogel

Advanced Materials, EarlyView.
Oxygen‐releasing hydrogels are widely used to support cell survival in 3D cultures and to promote wound healing. However, incorporating catalase to convert H2O2 into O2 often generates additional oxygen bubbles, leading to material instability which rarely addressed.
Sukulya Bunuasunthon, Isabel F. Amaral, Ana P. Pêgo, Michiya Matsusaki   +3 more
wiley   +1 more source

The effect of acute intermittent hypoxia on postprandial triglyceride levels in humans: a randomized crossover trial

Journal of Translational Medicine, 2021
Background Obstructive sleep apnea (OSA), a sleep disorder frequently observed in individuals living with obesity, consists of repeated involuntary breathing obstructions during sleep, leading to intermittent hypoxia (IH).
Renée Morin, Jean-François Mauger, Ruwan Amaratunga, Pascal Imbeault   +3 more
doaj   +1 more source

Mechanism‐Driven Nanoformulations for Cognitive Impairment Induced by Intermittent Hypoxia and Periodontitis

Advanced Materials, EarlyView.
Clinically, intermittent hypoxia (IH) is often accompanied by periodontitis, which accelerates cognitive impairment induced by IH. Novel Janus mesoporous gold‐silica nanoformulations (RVG‐Au&mSiO2‐TPP‐VB) enable intranasal delivery, achieve hierarchical targeting to neuronal mitochondria, effectively scavenge reactive oxygen species, inhibit the HIF‐1α/
Kai‐Run Zhang, Tianbao Zhu, An‐Qi Liu, Jia‐Jia Deng, Ya‐Li Han, Sheng‐Cai Qi, Xue Liu, Tian‐Yi Jiang, Ming‐Rui Zhai, Yu‐Ying He, Xiu‐Juan Li, Hong‐Ting Da, Rui Xu, Xiaomin Li, Jun Gao, Yue‐Hua Liu   +15 more
wiley   +1 more source