Results 11 to 20 of about 38,089 (218)

Sustained and intermittent hypoxia differentially modulate primary monocyte immunothrombotic responses to IL-1β stimulation

Frontiers in Immunology, 2023
Venous thromboembolism (VTE) is a leading cause of preventable deaths in hospitals, and its incidence is not decreasing despite extensive efforts in clinical and laboratory research. Venous thrombi are primarily formed in the valve pockets of deep veins,
Casper J.E. Wahlund, Safak Çaglayan, Paulo Czarnewski, Paulo Czarnewski, John-Bjarne Hansen, John-Bjarne Hansen, Omri Snir, Omri Snir   +7 more
doaj   +1 more source

Intermittent hypoxia can aggravate motor neuronal loss and cognitive dysfunction in ALS mice.

PLoS ONE, 2013
BackgroundPatients with ALS may be exposed to variable degrees of chronic intermittent hypoxia. However, all previous experimental studies on the effects of hypoxia in ALS have only used a sustained hypoxia model and it is possible that chronic ...
Sung-Min Kim, Heejaung Kim, Jeong-Seon Lee, Kyung Seok Park, Gye Sun Jeon, Jeeheun Shon, Suk-Won Ahn, Seung Hyun Kim, Kyung Min Lee, Jung-Joon Sung, Kwang-Woo Lee   +10 more
doaj   +1 more source

Expression of Hypoxia-Inducible Factor-1α and Myoglobin in Rat Heart as Adaptive Response to Intermittent Hypobaric Hypoxia Exposure

Hayati Journal of Biosciences, 2017
The aim of this study was to investigate the influence of intermittent hypobaric hypoxia on the expression hypoxia adaptation proteins, namely hypoxia inducibla factor-1a (HIF-1a) and myoglobin (Mb).
Margaretha Herawati, Wardaya, Wawan Mulyawan, Fanny Septiani Farhan, Frans Ferdinal, Sri Widia A. Jusman, Mohamad Sadikin   +6 more
doaj   +1 more source

Effect of TGF-β1 on intermittent hypoxia induced autophagy in hippocampal neurons

Di-san junyi daxue xuebao, 2021
Objective To investigate the effect of TGF-β1 on autophagy in hippocampal neurons induced by intermittent hypoxia. Methods In vivo experiment: Twelve SD rats were randomly divided as control group (N group) and intermittent hypoxia group (IH group ...
WANG Xin, LIU Zhili, HUANG Yinpei, YU Dan, LI Bing   +4 more
doaj   +1 more source

Expression of Hypoxia-Inducible Factor-1α and Myoglobin in Rat Heart as Adaptive Response to Intermittent Hypobaric Hypoxia Exposure

Hayati Journal of Biosciences, 2018
The aim of this study was to investigate the influence of intermittent hypobaric hypoxia on the expression hypoxia adaptation proteins, namely hypoxia inducibla factor-1a (HIF-1a) and myoglobin (Mb).
Margaretha Herawati, . Wardaya, Wawan Mulyawan, Fanny Septiani Farhan, Frans Ferdinal, Sri Widia A. Jusman, Mohamad Sadikin   +6 more
doaj   +1 more source

Intermittent Hypoxia Alters Gene Expression in Peripheral Blood Mononuclear Cells of Healthy Volunteers.

PLoS ONE, 2015
Obstructive sleep apnea is associated with high cardiovascular morbidity and mortality. Intermittent hypoxia of obstructive sleep apnea is implicated in the development and progression of insulin resistance and atherosclerosis, which have been attributed
Vsevolod Y Polotsky, Shannon Bevans-Fonti, Dmitry N Grigoryev, Naresh M Punjabi   +3 more
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Research on Intermittent Hypoxia Training in Sports Based on Graph Neural Network

Applied Artificial Intelligence, 2023
To enhance the efficacy of intermittent hypoxia training in sports, this study presents an intelligent training model that utilizes a graph neural network.
Guolong Li, Haixia Li, Jiyong Lv
doaj   +1 more source

Severe Intermittent Hypoxia Modulates the Macrophage Phenotype and Impairs Wound Healing Through Downregulation of HIF-2α

Nature and Science of Sleep, 2022
Lihong Chen,1 Yunyi Gao,2 Yan Li,1 Chun Wang,1 Dawei Chen,1 Yun Gao,1 Xingwu Ran1 1Innovation Center for Wound Repair, Diabetic Foot Care Center, Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, 610041, People’
Chen L, Gao Y, Li Y, Wang C, Chen D, Gao Y, Ran X   +6 more
doaj  

Microbiota Modulates Cardiac Transcriptional Responses to Intermittent Hypoxia and Hypercapnia

Frontiers in Physiology, 2021
The microbiota plays a critical role in regulating organismal health and response to environmental stresses. Intermittent hypoxia and hypercapnia, a condition that represents the main hallmark of obstructive sleep apnea in humans, is known to induce ...
Dan Zhou, Jin Xue, Yukiko Miyamoto, Orit Poulsen, Lars Eckmann, Gabriel G. Haddad, Gabriel G. Haddad, Gabriel G. Haddad   +7 more
doaj   +1 more source

Effects of Intermittent and Chronic Hypoxia on Fish Size and Nutrient Metabolism in Tiger Puffer (Takifugu rubripes)

Animals
Intermittent and chronic hypoxia are common stresses to marine fish, but the different responses of fish to intermittent and chronic hypoxia have not been well-known.
Qiang Ma, Renxiao Zhang, Yuliang Wei, Mengqing Liang, Houguo Xu   +4 more
doaj   +1 more source