Results 31 to 40 of about 806,096 (311)

Rationale and study design of intravenous loop diuretic administration in acute heart failure. DIUR-AHF [PDF]

open access: yes, 2017
Aims: Although loop diuretics are the most commonly used drugs in acute heart failure (AHF) treatment, their short-term and long-term effects are relatively unknown.
Di Somma, Salvatore   +5 more
core   +1 more source

Retrospective multicentre matched cohort study comparing safety and efficacy outcomes of intermittent-infusion versus continuous-infusion vancomycin.

open access: yesJournal of Antimicrobial Chemotherapy, 2020
BACKGROUND Patients with good renal function receiving intermittent-infusion vancomycin (IIV) may require total daily doses ≥4 g to achieve trough concentrations of 15-20 mg/L, increasing the risk of vancomycin-associated nephrotoxicity.
Nathan H Ma   +8 more
semanticscholar   +1 more source

Positive autoregulation of GDNF levels in the ventral tegmental area mediates long-lasting inhibition of excessive alcohol consumption. [PDF]

open access: yes, 2011
Glial cell line-derived neurotrophic factor (GDNF) is an essential growth factor for the survival and maintenance of the midbrain dopaminergic (DA-ergic) neurons.
Ahmadiantehrani, S   +3 more
core   +3 more sources

Variable versus fixed-rate infusion of phenylephrine during cesarean delivery: a randomized controlled trial

open access: yesBMC Anesthesiology, 2019
Background Phenylephrine is the most commonly used vasopressor for prophylaxis against maternal hypotension during cesarean delivery; however, the best regimen for its administration is not well established.
Ahmed Hasanin   +13 more
doaj   +1 more source

Piperacillin Steady State Concentrations in Target Tissues Relevant for PJI Treatment—A Randomized Porcine Microdialysis Study Comparing Continuous Infusion with Intermittent Short-Term Infusion

open access: yesAntibiotics, 2023
(1) Introduction: Piperacillin is a common antibiotic choice in the treatment of periprosthetic joint infections (PJI) caused by Pseudomonas aeruginosa.
Hans Christian Rasmussen   +9 more
doaj   +1 more source

Continuous versus Intermittent Bolus Epidural Anaesthesia in Elderly Surgical Patients

open access: yesJournal of Nepal Medical Association, 2003
A prospective study of 70 elderly conventionally continuously randomized patients was done to compare the haemodynamic changes produced during continuous infusion versus intermittent bolus epidural anaesthesia. The hemodynamic parameters (Blood pressure,
XK Yin, ZG Xiang, A Prasai, N Lamichhane
doaj   +1 more source

Nomenclature for renal replacement therapy and blood purification techniques in critically ill patients: practical applications [PDF]

open access: yes, 2016
This article reports the conclusions of the second part of a consensus expert conference on the nomenclature of renal replacement therapy (RRT) techniques currently utilized to manage acute kidney injury and other organ dysfunction syndromes in ...
Bagshaw, S. M.   +66 more
core   +4 more sources

Intermittent levosimendan infusion in ambulatory patients with end-stage heart failure: a systematic review and meta-analysis of 984 patients

open access: yesHeart Failure Reviews, 2021
We sought to synthesize the available evidence regarding safety and efficacy of intermittent levosimendan (LEVO) infusions in ambulatory patients with end-stage heart failure (HF).
H. Elsherbini   +9 more
semanticscholar   +1 more source

The decrease in growth hormone (GH) response after repeated stimulation with GH-Releasing hormone is partly caused by an elevation of somatostatin tonus. [PDF]

open access: yes, 1996
Repeated injection of GHRH leads to a decrease in the GH response in normal subjects. Arginine (Arg) stimulates GH secretion by suppression of hypothalamic somatostatin.
Mehltretter, Gerhard   +5 more
core   +1 more source

Dosing profile profoundly influences nicotinic acid's ability to improve metabolic control in rats

open access: yesJournal of Lipid Research, 2015
Acute nicotinic acid (NiAc) administration results in rapid reduction of plasma FFA concentrations. However, sustained NiAc exposure is associated with tolerance development resulting in return of FFA to pretreatment levels.
Tobias Kroon   +4 more
doaj   +1 more source

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