Results 91 to 100 of about 1,094,836 (297)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Some advantages of three-layer medium-density fibreboard as compared to the traditional single-layer one

open access: yesJournal of Wood Science, 2019
The aim of the study was to develop three-layer medium-density fibreboard (MDF) manufacture by adding the coarse fibres in the middle layer, like three-layer particleboard.
Turgay Akbulut, Nadir Ayrilmis
doaj   +1 more source

Mean-Reverting Stochastic Processes, Evaluation of Forward Prices and Interest Rates [PDF]

open access: yes
We consider mean-reverting stochastic processes and build self-consistent models for forward price dynamics and some applications in power industries. These models are built using the ideas and equations of stochastic differential geometry in order to ...
Aguero-Granados, M. A., Makhankov, V. G.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

PENGARUH BAHAN PENGAWETAN PHOXIM TERHADAP SIFAT PAPAN PARTIKEL KAYU KARET (hevea brasiliensis) (effect of phoxim preservation on the properties of rubber wood particleboard (hevea brasiliensis))

open access: yesJurnal Penelitian Hasil Hutan (Journal of Forest Products Research), 2017
The objectives of the study was to determine the effect of phoxim on the properties of rubber wood particleboard (Hevea brasiliensis ) phoxim concentration used were 0.05,1, 1.5 and 2 % based on particle dry weight.
Rodjak Memed   +2 more
doaj   +1 more source

Primary and secondary dissociation pathways in the ultraviolet photolysis of Cl_2O [PDF]

open access: yes, 1994
The photodissociation of dichlorine monoxide (Cl_2O) at 308, 248, and 193 nm was studied by photofragment translational energy spectroscopy. The primary channel upon excitation at 308 and 248 nm was Cl–O bond fission with production of ClO+Cl. A fraction
Minton, Timothy K.   +3 more
core  

Orthorhombic Phase of Crystalline Polyethylene: A Constant Pressure Path Integral Monte Carlo Study

open access: yes, 1997
In this paper we present a Path Integral Monte Carlo (PIMC) simulation of the orthorhombic phase of crystalline polyethylene, using an explicit atom force field with unconstrained bond lengths and angles.
A. A. Gusev   +18 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Origin of non-linear piezoelectricity in III-V semiconductors: Internal strain and bond ionicity from hybrid-functional density functional theory

open access: yes, 2015
We derive first- and second-order piezoelectric coefficients for the zinc-blende III-V semiconductors, {Al,Ga,In}-{N,P,As,Sb}. The results are obtained within the Heyd-Scuseria-Ernzerhof hybrid-functional approach in the framework of density functional ...
Caro, Miguel A.   +2 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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