Results 111 to 120 of about 8,905 (245)
Do Moral Beliefs Motivate Action? [PDF]
Ethical Theory Moral Pract, 2023 Díaz R.
europepmc +1 more source
What to believe about your belief that you're in the good case [PDF]
, 2019 Going about our daily lives in an orderly manner requires us, once we are aware of them, to dismiss many metaphysical possibilities. We take it for granted that we are not brains in vats, or living in the Matrix, or in an extended dream.
Worsnip, Alex
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Place Goes Wrong in Treating Mind-brain Relationship
Journal of Philosophical Investigations, 2015 U. T. Place claims that philosophical problems concerning the true nature of mind-brain relationship disappears or is settled adhering to materialism, especially type identity theory of mind. He takes above claim as a reasonable scientific hypothesis.
Mahdi Soleimani Khourmouji
doaj
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Allameh Tabataba'i and Finiss on Moral Motivations: A Comparative Study [PDF]
اخلاق وحیانی, 2017 In the psychology of ethics, there is a question concerning the true nature of moral motivations; are they internal or external motivations, are they self-controlled or not?
rahim dehghan
doaj
How Far we Can Go Without Looking Under the Skin: The Bounds of Cognitive Science
Studies in Logic, Grammar and Rhetoric, 2015 The aim of this paper is to discuss the concept of distributed cognition (DCog) in the context of classic questions posed by mainstream cognitive science.
Afeltowicz Łukasz, Wachowski Witold
doaj +1 more source
Evidence, Epistemic Luck, Reliability, and Knowledge. [PDF]
Acta Anal, 2022 Engel M.
europepmc +1 more source
FEBS Open Bio, EarlyView.NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source