Results 81 to 90 of about 182,993 (316)
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Spatial and temporal disaggregation of anthropogenic CO2 emissions from the City of Cape Town
This paper describes the methodology used to spatially and temporally disaggregate carbon dioxide emission estimates for the City of Cape Town, to be used for a city-scale atmospheric inversion estimating carbon dioxide fluxes. Fossil fuel emissions were
Alecia Nickless+2 more
doaj +1 more source
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu+12 more
wiley +1 more source
Remarks on Interpolation of Functions by Polynomials
We present some new formulas for interpolations of functions by polynomials. We apply them to some special functions.
Czekalski Stefan
doaj +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
Los «episodios» del Guzmán de Alfarache y del Quijote
My aim is to compare the way in which Cervantes and Alemán tackle the problem of how to interpolate episodes or digressions in Don Quijote and Guzmán de Alfarache respectively.
Anthony Close
doaj +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
A Fast Segmentation and Efficient Slice Reconstruction Technique for Head CT Images
The three-dimensional (3D) reconstruction of medical images usually requires hundreds of two-dimensional (2D) scan images. Segmentation, an obligatory part in reconstruction, needs to be performed for all the slices consuming enormous storage space and ...
Thasneem A.A. Haseena+2 more
doaj +1 more source