Results 71 to 80 of about 1,938,741 (297)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Balancing Act: Exploring the Interplay Between Human Judgment and Artificial Intelligence in Problem-solving, Creativity, and Decision-making

open access: yesIgMin Research
This study explores the repercussions of excessive reliance on Artificial Intelligence (AI) on human cognitive processes, specifically targeting problem-solving, creativity, and decision-making.
Al-Zahrani Abdulrahman M
semanticscholar   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Prohibited AI Practices in Healthcare under the European Artificial Intelligence Act.

open access: yesJournal of Law, Medicine & Ethics
The European Union's Artificial Intelligence Act introduces a novel regulatory category of "unacceptable risk," prohibiting specific AI practices that are deemed fundamentally incompatible with human rights and ethical principles.
Hannah van Kolfschooten
semanticscholar   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

John Pier, Configurazioni narrative

open access: yesEnthymema, 2009
The article moves in the direction of an intertextual narratology integrating semiotic reflection with logic, focusing on the concept of “configuration” as model of comprehension (Mink, Ricoeur).
Alessandra Diazzi
doaj   +1 more source

A “Potency-Act” Interpretation of Quantum Physics

open access: yesJournal of Modern Physics, 2021
Some considerations are presented on the so called “ontological interpretations” of quantum physics, starting from a remark by Werner Heisenberg on the relation between the probabilistic character of quantum states and the Aristotelian notion of “potency”.
openaire   +3 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

„Книга художника” как интермедиальный дискурс

open access: yesPoznańskie Studia Slawistyczne, 2012
The article is devoted to an analysis of various representations of the “Artist’s book” genre in modern Russian and world art. These representationsfunction within the framework of the paradigm of art that refers to issues such as inter- and multimedia,
Grażyna Bobilewicz
doaj   +1 more source

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