Results 91 to 100 of about 31,985 (192)

Exercise Restriction Does Not Change Outcome in Dogs After Diagnosis of Acute Non‐Compressive Nucleus Pulposus Extrusion, Fibrocartilaginous Embolism, or Hydrated Nucleus Pulposus Extrusion

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background Acute non‐compressive nucleus pulposus extrusion (ANNPE), fibrocartilaginous embolism (FCE), and hydrated nucleus pulposus extrusion (HNPE) all present with acute to peracute onset of myelopathic signs in dogs, for which treatment usually is medical.
Katherine Phillips, Paul Freeman
wiley   +1 more source

Conceptual Design and Parametric Optimization of a New Multileveled Horsetail Structure for Bicycle Helmets

Advanced Engineering Materials, Volume 27, Issue 11, June 2025.
This study aims to explore the feasibility of using a structure inspired by the features of horsetail and human spine as the potential helmet liner, targeting at mitigation of acceleration‐induced injuries. A parametric study is conducted to investigate the effect of individual geometrical variables in the design, indicating its capability to reduce ...
Bing Leng, Dong Ruan, Shanqing Xu, Kwong Ming Tse   +3 more
wiley   +1 more source

Role of macrophage in intervertebral disc degeneration. [PDF]

Bone Res
Dou Y, Zhang Y, Liu Y, Sun X, Liu X, Li B, Yang Q.   +6 more
europepmc   +1 more source

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin, Chuling Li, Zhaoyi Wu, Zhenquan Tang, Jingfang Xie, Guoquan Wei, Zhiwen Yang, Senlin Huang, Yijin Chen, Xinzhong Li, Yanmei Chen, Wangjun Liao, Yulin Liao, Guojun Chen, Hao Zheng, Jianping Bin   +15 more
wiley   +1 more source

Targeting Piezo1 channel to alleviate intervertebral disc degeneration. [PDF]

J Orthop Translat
Li F, Chen M, Zhang M, Chen S, Qu M, He S, Wang L, Wu X, Xiao G.   +8 more
europepmc   +1 more source

In Vitro Validation of Pulsed Electromagnetic Field (PEMF) as an Effective Countermeasure Against Inflammatory-Mediated Intervertebral Disc Degeneration. [PDF]

JOR Spine
ABSTRACT Background Intervertebral disc (IVD) degeneration (IDD) is the main contributor to chronic low back pain (LBP), the leading cause of disability worldwide, with a significant impact on the quality of life and health of common people. The etiology of IDD is still unclear, but it has been largely demonstrated the crucial role of inflammation and ...
Guarnaccia L, Begani L, Pileggi S, Pluderi M, Borsa S, Fanizzi C, Rizzaro MD, Fiore G, Fontana L, Campanella R, Cordiglieri C, Gaudino C, Alotta GA, Miozzo M, Garzia E, Barilla E, Fassina L, Riboni L, Locatelli M, Marfia G, Navone SE.   +20 more
europepmc   +2 more sources

The intervertebral discs

Journal of British Surgery, 1931
N. Smith, Ross Bournemouth
openaire   +2 more sources

Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun, Yangyang Shi, Chen Yan, Shunmin Wang, Linhui Han, Fudong Li, Ximing Xu, Yuan Wang, Jingchuan Sun, Zijian Kang, Jiangang Shi   +10 more
wiley   +1 more source

Molecular Mechanisms of Intervertebral Disc Degeneration Induced by <i>Propionibacterium acnes</i>. [PDF]

Biomed Res Int
Yang W, Xu Y, Tan Y, Lin J, Chen H, Li S, Miao H, Ye D.   +7 more
europepmc   +1 more source

Sirt6 deficiency promotes senescence and age-associated intervertebral disc degeneration in mice. [PDF]

Bone Res
Ramteke P, Watson B, Toci M, Tran VA, Johnston S, Tsingas M, Barve RA, Mitra R, Loeser RF, Collins JA, Risbud MV.   +10 more
europepmc   +1 more source