Results 91 to 100 of about 93,770 (350)

The causality between smoking and intervertebral disc degeneration mediated by IL-1β secreted by macrophage: A Mendelian randomization study

open access: yesHeliyon
There is still a lack of high-level evidence regarding the causal relationship between smoking and intervertebral disc degenerative diseases. This study utilized data from genome wide analysis studies and conducted two-sample Mendelian randomization ...
Zhaopu Han, Yicheng Chen, Xiaojian Ye
doaj   +1 more source

Occurrence and Regional Distribution of TRAIL and DR5 on Temporomandibular Joint Discs: Comparison of Disc Derangement with and without Reduction [PDF]

open access: yes, 2010
Background Tumor necrosis factor (TNF)–related apoptosis-inducing ligand (TRAIL) is an apoptosis-inducing member of the TNF gene family which triggers apoptotic signals by interaction with its receptors.
Almeida, Luis Eduardo   +3 more
core   +1 more source

Morphological variation in atlas and axis of Neotropical spiny rats (Rodentia, Echimyidae)

open access: yesThe Anatomical Record, EarlyView.
Abstract The unique morphologies of the first two cervical vertebrae, the atlas and axis, represent a significant innovation in mammalian evolution. These structures support the weight of the head and enable intricate movements of the head and neck.
Thomas Furtado da Silva Netto   +3 more
wiley   +1 more source

Lubricin Immunohistochemical Expression in Human Temporomandibular Joint Disc with Internal Derangement [PDF]

open access: yes, 2011
Lubricin is a chondroprotective, mucinous glycoprotein which contribute to joint lubrication, especially to boundary lubrication and maintains joint integrity.
Almeida, Luis Eduardo   +2 more
core   +2 more sources

Patterns of spinal motion, kinematic spaces and the land‐to‐sea transition in carnivorans

open access: yesThe Anatomical Record, EarlyView.
Using 3D reconstructions, we quantify intervertebral joint mobility to investigate how cervical, thoracic, and lumbar vertebral regions evolved distinct kinematic roles in pinnipeds. The findings reveal lineage‐specific adaptations for swimming and highlight the functional significance of vertebral joint flexibility in ecological transitions.
Juan Miguel Esteban   +3 more
wiley   +1 more source

Evaluation of Intervertebral Disc Space Width Between 10th and 11th Thoracic Vertebrae in Cats Using Radiography and Magnetic Resonance Imaging

open access: yesVeterinary Medicine and Science
Background It is well known that the T10–T11 intervertebral disc space is usually narrower than the adjacent intervertebral disc spaces in most dogs.
Jiwon Kim   +4 more
doaj   +1 more source

Overactivation of NF-kB pathway can induce apoptosis by down-regulating glycolysis in human degenerative nucleus pulposus cells

open access: yesHeliyon
Intervertebral disc herniation, a prevalent condition in spinal surgery that frequently results in low back pain and lower limb dysfunction, significantly impacting patients' quality of life.
Pan Tang, Bo Liu
doaj   +1 more source

Pathologic Features of the Intervertebral Disc in Young Nova Scotia Duck Tolling Retrievers Confirms Chondrodystrophy Degenerative Phenotype Associated With Genotype. [PDF]

open access: yes, 2019
Chondrodystrophy results in predictable and progressive biochemical and structural changes to the intervertebral disc, resulting in early onset degeneration and dystrophic mineralization of the disc.
Bannasch, Danika   +5 more
core  

MRI Evaluation of Lumbar Disc Degenerative Disease [PDF]

open access: yes, 2015
Introduction: Lower back pain secondary to degenerative disc disease is a condition that affects young to middle-aged persons with peak incidence at approximately 40 y.
Mehta, Chetan   +3 more
core   +2 more sources

OGFRL1 deficiency causes CRMO via pathological osteoclastogenesis, with therapeutic response to TNF inhibitor

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong   +9 more
wiley   +1 more source

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