Results 151 to 160 of about 43,436 (258)

Nucleus Pulposus Resorption Following a Paraspinal Hook‐Needle Intervention for Lumbar Disc Herniation: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT The paraspinal hook‐needle intervention is a minimally invasive needle‐based procedure performed under local anesthesia using a specialized hook‐shaped needle at clinically selected lumbar segments. We report the case of a 70‐year‐old woman who presented with intermittent low back pain for more than 10 years, recently aggravated and ...
Mengying Xiao, Zhengchao Cai, Hairui Zhu, Shuanglin Mou, Wensheng Zhu   +4 more
wiley   +1 more source

Ubiquitination in intervertebral disc degeneration: from mechanisms to potential therapeutic strategies. [PDF]

J Orthop Translat
Liu X, Kang X.
europepmc   +1 more source

SARS‐CoV‐2 Spike Peptides Trigger Nociceptive Responses Through Spinal TLR4 Pathways

European Journal of Pain, Volume 30, Issue 7, August 2026.
ABSTRACT Background Pain is a common neurological manifestation of COVID‐19, yet the mechanisms by which SARS‐CoV‐2 spike protein fragments contribute to nociceptive processing remain poorly understood. We investigated whether spike‐derived peptides directly activate spinal neuroimmune pathways involved in pain signalling.
Bruno Eduardo Silva, Rayner Ribeiro Cardoso, Lívia Maria Ribeiro Rosário, João Paulo Prado, Rafaela Silva dos Santos, Flávio Protasio Veras, Mylena de Souza, Eduardo Maffud Cilli, Danilo Olivier, Marco Antonio de Andrade Belo, Ives Charlie‐Silva, Ester Siqueira Caixeta, Angel Roberto Barchuk, Albená Nunes‐Silva, Thiago Roberto Lima Romero, Giovane Galdino   +15 more
wiley   +1 more source

Lactate and lactylation in intervertebral disc degeneration. [PDF]

Front Mol Biosci
Liu Y, Yang J, Wang Z, Fu J, Liu H, Lu Z, Dong J, Li Z, Mao Q, Li C, Ma H.   +10 more
europepmc   +1 more source

Keratan Sulfate: An Electroconductive Glycosaminoglycan at the Interface of Sensory Perception and Neural Signaling

Journal of Neuroscience Research, Volume 104, Issue 8, August 2026.
Laboratory studies show KS has electroconductive properties with the ability to trap and transport protons in neurotransductive processes (Grotthuss proton shuttling). This maintains electrochemical gradients and fluxes at the neuronal cell surface in neural activation. Such processes are central to neuronal cell signaling and communication.
James Melrose
wiley   +1 more source

A nucleic acid regulation strategy under mechanical stress for intervertebral disc degeneration treatment. [PDF]

Bioact Mater
Wang W, Huo W, Qian D, Hou P, Su C, Sun S, Yao Y, Ma J, Hou L, Wu J, Chen Y, Hu F, Zhao T, Zhang X.   +13 more
europepmc   +1 more source

Multicenter Assessment of Combined Brain and Cervical Spinal cord 3T MP2RAGE T1 Measurements for Reliable Tissue Microstructure Quantification

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
Reliability of simultaneous brain and spinal cord magnetization‐prepared two rapid acquisition gradient echoes (MP2RAGE) T1 measurements was evaluated in a multicentre context. Mean intra‐site/inter‐site/between‐participant coefficients of variation (COV) were 0.4/0.9/2.3% for the brain ROIs and 2.0/2.4/1.7% for the cSC, confirming the potential of T1 ...
Malo Gaubert, Benoit Combès, Henitsoa Rasoanandrianina, Jean‐Christophe Ferré, Alice Dufey, Raphaël Chouteau, Bertrand Audoin, Jean Pelletier, Sarah Demortière, Anne Kerbrat, Elise Bannier, Virginie Callot   +11 more
wiley   +1 more source

Immune Mechanisms and Pain in Intervertebral Disc Degeneration. [PDF]

J Inflamm Res
Cheng H, Wang L, Huang C, Yang Z, Wu H, Fang Z.   +5 more
europepmc   +1 more source

Directional X‐Ray Scattering and Microtomography for Laboratory‐Based Imaging of Fibrous Materials and Biological Tissues

Small Science, Volume 6, Issue 8, August 2026.
A compact laboratory X‐ray system enables directional dark‐field imaging and tomography with sensitivity to scattering along two orthogonal directions. The approach provides volumetric mapping of sub‐resolution microstructure in engineering and biological samples, which reveals structural heterogeneity, fiber organization, and anisotropic scattering ...
Carlos Navarrete‐León, Álvaro José González‐Grajales, Harry Allan, Adam Doherty, Alissa Parmenter, Rocco D’Antuono, David Bate, Alberto Astolfo, Silvia Cipiccia, Charlotte K. Hagen, Alessandro Olivo, Marco Endrizzi   +11 more
wiley   +1 more source

Gas therapy: an innovative application for intervertebral disc degeneration. [PDF]

Med Gas Res
Cai L, Ru B, Ren H, Cai F, Zeng L, Yang J, Wang S, Zhang H, Li Y, Zhang L.   +9 more
europepmc   +1 more source