Results 151 to 160 of about 43,248 (263)

Bilateral Avascular Necrosis of the Femoral Heads in Ankylosing Spondylitis Requiring Staged Total Hip Arthroplasty: A Case Report of Diagnostic and Therapeutic Challenges

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Ankylosing spondylitis (AS) is a chronic immune‐mediated inflammatory arthropathy primarily affecting the axial skeleton but may involve peripheral joints, particularly the hips. Avascular necrosis (AVN) of the femoral head represents a severe, underrecognized complication whose pathogenesis in AS is multifactorial—encompassing disease ...
Syeda Simrah Shah, Muhammad Ahsan, Tehreem Farooq, Mirza Daniyal Baig, Mirza Mohammad Ali Baig, Mohammed Hammad Jaber Amin   +5 more
wiley   +1 more source

Ubiquitination in intervertebral disc degeneration: from mechanisms to potential therapeutic strategies. [PDF]

J Orthop Translat
Liu X, Kang X.
europepmc   +1 more source

Bilateral Brucellar Sacroiliitis Mimicking Tuberculous or Inflammatory Spondyloarthropathy: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Brucellosis is a zoonotic infection, endemic in rural areas. It is caused by Brucella species, which are transmitted through the intake of unpasteurized dairy products and contact with infected animals. Sacroiliac joint involvement is common in brucellosis and typically presents as unilateral sacroiliitis. Contrarily, bilateral sacroiliitis is
Zia Ullah, Zain Ul Abedeen, Muhammad Kashif Habib, Naeem Ullah, Abad Ur Rehman   +4 more
wiley   +1 more source

A nucleic acid regulation strategy under mechanical stress for intervertebral disc degeneration treatment. [PDF]

Bioact Mater
Wang W, Huo W, Qian D, Hou P, Su C, Sun S, Yao Y, Ma J, Hou L, Wu J, Chen Y, Hu F, Zhao T, Zhang X.   +13 more
europepmc   +1 more source

An Unusual Cause of Diffuse Bone Pain in a Long‐Term Dialysis Patient: A Case Report of β2‐Microglobulin Amyloid Arthropathy

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Dialysis‐related amyloidosis (DRA) results from β2‐microglobulin accumulation in patients on long‐term hemodialysis, typically manifesting after 5–10 years. While well‐documented in developed countries, reports from sub‐Saharan Africa remain scarce.
Yannick Laurent Tchenadoyo Bayala, Mohamed Hanas Mama Sika, Marina Saley André Hamidou, Issa Ouedraogo, Rachidatou Kafando, Bakoubassé Aïssata Son, Wendyam Nadège Yameogo, Wendlassida Joëlle Stéphanie Zabsonré/Tiendrébéogo, Dieu‐Donné Ouedraogo   +8 more
wiley   +1 more source

A Novel Decomposition‐Based Growth Model for Simulating Stress‐Modulated Spinal Growth

International Journal for Numerical Methods in Biomedical Engineering, Volume 42, Issue 6, June 2026.
This study introduces the first decomposition‐based finite‐strain growth model for a simplified Functional Spinal Unit, where growth occurs simultaneously with mechanical loading. The approach eliminates the major physical inconsistency of sequential methods—growth in an artificial stress‐free configuration—while preventing mesh distortion and ...
Serhat Onur Çakmak, Ercan Gürses
wiley   +1 more source

Lactate and lactylation in intervertebral disc degeneration. [PDF]

Front Mol Biosci
Liu Y, Yang J, Wang Z, Fu J, Liu H, Lu Z, Dong J, Li Z, Mao Q, Li C, Ma H.   +10 more
europepmc   +1 more source

Gingerol-loaded hollow manganese dioxide nanoparticles attenuate intervertebral disc oxidative stress. [PDF]

RSC Adv
Liu X, Lu B, Zhou Y, Zhang C, Shi F, Feng G, Luo X, Xiao D.   +7 more
europepmc   +1 more source

Secretome and Pathway Analysis of Stress Induced Disc Degeneration In Vitro

JOR SPINE, Volume 9, Issue 2, June 2026.
Integrated secretome and phosphoprotein profiling of human nucleus pulposus cells revealed that IL‐1β and TLR2/6 activation induce a shared degenerative program, defined by consistent upregulation of IL‐6, IL‐8, GRO‐α, ICAM‐1, and MMP‐7 and convergence on NF‐κB/AP‐1 signaling.
Exarchos Kanelis, Andrea Nüesch, Joseph Snuggs, Christine Lyn Le Maitre, Leonidas G. Alexopoulos   +4 more
wiley   +1 more source

Causal relationship between intervertebral disc degeneration and neurological disorders: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Cao X.
europepmc   +1 more source