Results 131 to 140 of about 45,415 (193)
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Immune-neural crosstalk in chronic low back pain: from intervertebral disc degeneration to pain sensitization. [PDF]
Wei J +5 more
europepmc +1 more source
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil +11 more
wiley +1 more source
Abstract figure legend We tested the hypothesis that cAMP binding to HCN2 channels in nociceptors is a causal driver of neuropathic pain by using TRIP8bnano, a synthetic peptide we previously developed as a selective antagonist of cAMP in HCN channels. TRIP8bnano effectively abolishes cAMP potentiation of HCN2 currents in small‐diameter DRG neurons and
Santiago I. Loya‐Lopez +7 more
wiley +1 more source
Retraction: Effectiveness of medical ozone injections into the intervertebral disc on relieving lumbosacral pain-a systematic review and meta-analysis. [PDF]
Frontiers Editorial Office.
europepmc +1 more source
Abstract In birds, the neural canal houses a variety of anatomical structures including the spinal cord, meninges, spinal vasculature, and respiratory diverticula. Among these, paramedullary diverticula and the extradural dorsal spinal vein may leave behind osteological correlates in the form of pneumatic foramina and fossae, and a bilobed geometry of ...
Jessie Atterholt +5 more
wiley +1 more source
Targeting the nuclear factor kappa B pathway for the medical management of intervertebral disc degeneration. [PDF]
Wang J +9 more
europepmc +1 more source
Abstract The upper carbonate concretion levels of the Romualdo Formation (Aptian, Brazil) have yielded several theropod dinosaur remains, including spinosaurids and the coelurosaurs Santanaraptor placidus and Mirischia asymmetrica, the phylogenetic affinities of which are controversial.
Rafael Delcourt +4 more
wiley +1 more source
Causal Effects of Plasma Metabolites on Intervertebral Disc Degeneration and Low Back Pain: A Mendelian Randomization Study. [PDF]
Zhu S +6 more
europepmc +1 more source

