Results 141 to 150 of about 43,248 (263)

Welfare and Physiological Consequences of Non‐Lethal Blood Sampling From the Caudal Vasculature of Atlantic Salmon (Salmo salar L.)

Journal of Fish Diseases, Volume 49, Issue 7, July 2026.
ABSTRACT The objective of this study was to evaluate welfare and health effects following single and repeated non‐lethal blood sampling from the caudal vasculature of Atlantic salmon. Two experiments were conducted at three different temperatures: a 6‐week freshwater experiment with fish weighing 50–100 g, undergoing up to four blood withdrawals, and a
Harriet Romstad, Camilla Karlsen, Silje Stensby‐Skjærvik, Alf Seljenes Dalum, Maria Banaszkiewicz, Simen Foyn Nørstebø, Jessica Louise Ray, Hege Lund, Torstein Kristensen, Christine Klykken   +9 more
wiley   +1 more source

Intervertebral Disc Elastography to Relate Shear Modulus and Relaxometry in Compression and Bending. [PDF]

Bioengineering (Basel)
Davis ZR, Gossett PC, Wilson RL, Kim W, Mei Y, Butz KD, Emery NC, Nauman EA, Avril S, Neu CP, Chan DD.   +10 more
europepmc   +1 more source

Magnetic Resonance Imaging Features of Intravascular Osteosarcoma Affecting the Ventral Internal Vertebral Venous Plexus Causing Cervical Myelopathy in a Dog

Veterinary Radiology &Ultrasound, Volume 67, Issue 4, July 2026.
ABSTRACT A 10.5‐year‐old male castrated Standard Poodle was referred for the evaluation of chronic C6–T2 myelopathy. MRI revealed a severe asymmetric enlargement of the ventral internal vertebral venous plexus, intervertebral/vertebral veins, and possibly the C6 basivertebral vein, with secondary mild spinal cord compression.
Robert Wise, Rachel Durrwachter, Nathan Fanzone, Wilfried Mai   +3 more
wiley   +1 more source

AI-driven reconstruction of the evidence architecture of hydrogel-based intervertebral disc repair research. [PDF]

Front Cell Dev Biol
Wang Y, Cheng J, Zhang C, Yan T, Tian Z, Liu J, Li Q, Wang Z.   +7 more
europepmc   +1 more source

SETD1A Regulates Glycolysis and Senescence of Nucleus Pulposus Cells via H3K4me3–HELZ2/PPARα‐HIF1α Axis to Drive Intervertebral Disc Degeneration

Advanced Science, Volume 13, Issue 34, 19 June 2026.
SETD1A is a key epigenetic regulator in NPCs during IDD. In normal NPCs, it sustains H3K4me3–HELZ2/PPARα–HIF1α signaling to maintain glycolytic energy metabolism and proliferation. In degenerated NPCs, reduced SETD1A disrupts this axis, impairing glycolysis and accelerating senescence, highlighting a promising therapeutic target for IDD.
Jiawei Fu, Xue Leng, Jiang Long, Zhengao Liao, Xiaoqin An, Xuezheng Ai, Dan Long, Changqing Li, Bo Huang, Yue Zhou, Shiwu Dong, Chencheng Feng   +11 more
wiley   +1 more source

Neuroimmune Activation in a Goat Model of Intervertebral Disc Degeneration. [PDF]

Cells
Augustin JA, Burt KG, Barrett C, Fainor M, Orozco BS, Schaer TP, Smith HE, Mauck RL, Gullbrand SE.   +8 more
europepmc   +1 more source

OGFRL1 Deficiency Causes Chronic Recurrent Multifocal Osteomyelitis Via Pathologic Osteoclastogenesis, With Therapeutic Response to Tumor Necrosis Factor Inhibitor

Arthritis &Rheumatology, Volume 78, Issue 6, Page 1318-1326, June 2026.
Objective To verify the pathogenesis of the opioid growth factor receptor like‐1 (OGFRL1) loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a patient with chronic recurrent multifocal osteomyelitis (CRMO) and to investigate the underlying mechanism.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

A Challenge-Oriented Review of Delivery Systems for Cell and Gene Therapies in Intervertebral Disc Degeneration. [PDF]

Bioengineering (Basel)
Wu W, Cheng Z, Gao H, Chen X, Wu W, Yu Z, Yang C, Zhang Y.   +7 more
europepmc   +1 more source

Safety and Tolerability of Different Total Neoadjuvant Therapies in Patients With Locally Advanced Rectal Cancer

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Total neoadjuvant therapy (TNT) is the standard treatment for locally advanced rectal cancer (LARC). Few studies have focused on the toxicity of TNT. Moreover, the differences in safety and tolerability between radiotherapy‐first and chemotherapy‐first strategies remain unclear.
Shohei Udagawa, Hiroki Osumi, Senzo Taguchi, Tatsuki Noguchi, Takashi Sakamoto, Shimpei Matsui, Toshiki Mukai, Tomohiro Yamaguchi, Shota Fukuoka, Koichiro Yoshino, Keitaro Shimozaki, Takeru Wakatsuki, Mariko Ogura, Akira Ooki, Keisho Chin, Kensei Yamaguchi, Takashi Akiyoshi, Eiji Shinozaki   +17 more
wiley   +1 more source

Identification and experimental validation of aging-related biomarkers in intervertebral disc degeneration. [PDF]

Sci Rep
Zhang F, Yuan L, Ding H, Lou Z, Li X.
europepmc   +1 more source