Results 31 to 40 of about 77,646 (205)

Application of single and cooperative different delivery systems for the treatment of intervertebral disc degeneration

Frontiers in Bioengineering and Biotechnology, 2022
Intervertebral disc (IVD) degeneration (IDD) is the most universal pathogenesis of low back pain (LBP), a prevalent and costly medical problem across the world.
Zongtai Liu, Changfeng Fu
doaj   +1 more source

Outcome of anterior lumbar interbody fusion : a retrospective study of clinical and radiologic parameters [PDF]

, 2017
Objective. This study aims to critically evaluate the long-term results of stand-alone anterior lumbar interbody fusion (ALIF), without use of rhBMP-2, as a therapeutic option for symptomatic patients with degenerative disc disease (DDD).
Caemaert, Jacques, COUVREUR, TIM, Everaert, Karel, Hallaert, Giorgio, HERREGODTS, PATRICK, Kalala Okito, Jean-Pierre, Pinson, Harry, Van Roost, Dirk   +7 more
core   +2 more sources

Role of macrophage in intervertebral disc degeneration

Bone Research
Intervertebral disc degeneration is a degenerative disease where inflammation and immune responses play significant roles. Macrophages, as key immune cells, critically regulate inflammation through polarization into different phenotypes. In recent years,
Yiming Dou, Yiming Zhang, Yang Liu, Xun Sun, Xinyu Liu, Bin Li, Qiang Yang   +6 more
doaj   +1 more source

Effects of Changes in Osmolarity on the Biological Activity of Human Normal Nucleus Pulposus Mesenchymal Stem Cells

Stem Cells International, 2022
The expansion and maintenance of the NPMSC (nucleus pulposus mesenchymal stem cell) phenotype are considered as potential therapeutic tools for clinical applications in intervertebral disc tissue engineering and regenerative medicine.
Hua Zhang, Wei Li, YaoHong Wu, Shengquan Zhang, Jie Li, Letian Han, Haoyu Chen, Ziyu Wang, Cailiang Shen, Yinshun Zhang, Hui Tao   +10 more
doaj   +1 more source

Development of a deep learning model for automatic detection of narrowed intervertebral disc space sites in caudal thoracic and lumbar lateral X-ray images of dogs

Frontiers in Veterinary Science
Intervertebral disc disease is the most common spinal cord-related disease in dogs, caused by disc material protrusion or extrusion that compresses the spinal cord, leading to clinical symptoms.
Junseol Park, Junseol Park, Hyunwoo Cho, Yewon Ji, Kichang Lee, Hakyoung Yoon, Hakyoung Yoon   +6 more
doaj   +1 more source

Association of magnetic resonance assessed disc degeneration and late clinical recurrence in dogs treated surgically for thoracolumbar intervertebral disc extrusions

Journal of Veterinary Internal Medicine, 2021
Background Radiographic signs of intervertebral disc mineralization are thought to indicate sites of future recurrence of disc extrusion (Hansen type I) but the relationship between evidence of disc degeneration on magnetic resonance imaging (MRI) and ...
Sara Longo, Sergio A. Gomes, Chiara Briola, Katherine Duffy, Mike Targett, Nick D. Jeffery, Paul Freeman   +6 more
doaj   +1 more source

The Comparison between Herniated and Non-Herniated Disc Levels Regarding Intervertebral Disc Space Height and Disc Degeneration, A Magnetic Resonance Study

Diagnostics, 2023
Purpose: The main purpose of this study was to evaluate the intervertebral disc height and intervertebral disc degeneration between the normal group and the group with disc herniation at the level of the L4–L5 intervertebral disc by MRI using the ...
Türkhun Çetin, Sevket Kahraman, Volkan Kızılgöz, Sonay Aydın   +3 more
doaj   +1 more source

An investigation into the effectiveness of collagenase for the percutaneous discolysis of thoracolumbar intervertebral discs in the dog : a thesis presented in partial fulfilment of the requirements for the degree of Master of Veterinary Science at Massey University [PDF]

, 1993
This investigation compared the effectiveness of chemonucleolysis with 500 units of collagenase, to lateral fenestration of the thoracolumbar intervertebral discs of the non-chondrodystrophoid dog.
Bray, Jonathan Peter
core  

Endogenous musculoskeletal tissue engineering - a focused perspective [PDF]

, 2012
Two major difficulties facing widespread clinical implementation of existing Tissue Engineering (TE) strategies for the treatment of musculoskeletal disorders are (1) the cost, space and time required for ex vivo culture of a patient’s autologous cells ...
Adam, Clayton
core   +2 more sources

Clarifying the nomenclature of intervertebral disc degeneration and displacement: from bench to bedside [PDF]

, 2014
As a significant determinant of low back pain, intervertebral disc degeneration (IDD) has attracted more and more attention of both investigators and physicians.
Samartzis, D, Wang, HQ
core