Results 91 to 100 of about 39,314 (264)
The FEBS Journal, EarlyView.The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka +3 more
wiley +1 more source
Mn-MIL-100@AKG alleviates intervertebral disc degeneration by regulating mitophagy
Materials Today BioCurrently, the therapy of intervertebral disc degeneration (IDD) mostly focuses on basic molecular causes. Research on the alterations of metabolites in the intervertebral disc prior to and following intervertebral disc degeneration (IDD) remains ...
Xianglong Chen +8 more
doaj +1 more source
Acta Orthopaedica et Traumatologica Turcica, 2020 Objectives: We investigated the relationship between the lumbosacral morphology and degree of intervertebral disc degeneration in a large sample of young patients. In addition, the relation between various morphological parameters (sacral table angle and
Tarkan Ergun +2 more
doaj +1 more source
ADAM10 Localization in Temporomandibular Joint Disk with Internal Derangement: An Ex Vivo Immunohistochemical Study [PDF]
, 2016 The purpose of this study was to determine the presence of ADAM10 in temporomandibular joint disk with internal derangement. Twenty-five paraffin blocks of displaced temporomandibular joint (TMJ) disk specimens from earlier investigations were retrieved ...
Almeida, Luis Eduardo +7 more
core +2 more sources
Journal of Fish Diseases, EarlyView.ABSTRACT The objective of this study was to evaluate welfare and health effects following single and repeated non‐lethal blood sampling from the caudal vasculature of Atlantic salmon. Two experiments were conducted at three different temperatures: a 6‐week freshwater experiment with fish weighing 50–100 g, undergoing up to four blood withdrawals, and a
Harriet Romstad +9 more
wiley +1 more source
Innovating intervertebral disc degeneration therapy: Harnessing the power of extracellular vesicles
Journal of Orthopaedic TranslationIntervertebral disc degeneration is the leading cause of low back pain, imposing significant burdens on patients, societies, and economies. Advancements in regenerative medicine have spotlighted extracellular vesicles as promising nanoparticles for ...
Shanfeng Chen +5 more
doaj +1 more source
Journal of Anatomy, EarlyView.This study characterizes a newly‐described intervertebral fat pad (IVFP) anterior to rat IVDs, with evidence for its existence in mice and human IVDs as well. In rats, the IVFP gradually degenerated following IVD injury with changes in adipocyte size and fibrous tissue infiltration, suggesting it could play a functional role in IVD health and ...
Niklas H. Koehne +7 more
wiley +1 more source
Outcome of anterior lumbar interbody fusion : a retrospective study of clinical and radiologic parameters [PDF]
, 2017 Objective. This study aims to critically evaluate the long-term results of stand-alone anterior lumbar interbody fusion (ALIF), without use of rhBMP-2, as a therapeutic option for symptomatic patients with degenerative disc disease (DDD).
Caemaert, Jacques +7 more
core +2 more sources
Orthopaedic Surgery, Volume 17, Issue 5, Page 1389-1396, May 2025.The research utilized a case–control approach to contrast patients experiencing unscheduled readmissions with those undergoing planned readmissions due to staged surgery. Findings indicated a 3.88% rate of unscheduled readmissions, mainly linked to adjacent segment disease, with 3.35% necessitating reoperation.
Wangmi Liu +5 more
wiley +1 more source
Bone ReportsIntervertebral Disc Degeneration is a pathophysiological condition that primarily affects the spinal discs, causing back pain and neurological deficits.
Gyanoday Tripathi +2 more
doaj +1 more source