Results 101 to 110 of about 39,314 (264)

Establishing a Staging System for Adjacent Segment Disease and Exploring Its Significance in Guiding Surgical Decisions: A Retrospective Study

Orthopaedic Surgery, Volume 17, Issue 5, Page 1418-1432, May 2025.
Developed a staging system for adjacent segment disease based on degeneration characteristics. Verified the feasibility and reliability of stage‐guided surgical decision‐making through surgical data, radiological data, and follow‐up data. This staging system was closely correlated with intervertebral disc degeneration and disc height while also ...
Changpeng Qu, Jianwei Guo, Hao Tao, Chuanli Zhou, Kai Zhu, Yihao Sun, Lei Li, Zhiming Liu, Hao Zhang, Xuexiao Ma   +9 more
wiley   +1 more source

Detrimental Effect of Low‐Magnitude High‐Frequency Vibration in an Ex Vivo Model of Intervertebral Disc Degeneration Despite Estrogen Treatment [PDF]

JOR Spine
Low‐magnitude high‐frequency vibration (LMHFV), with or without 17β‐oestradiol (E2), exacerbated papain‐induced bovine intervertebral disc degeneration, reducing cell viability, impairing matrix production, and increasing inflammation. E2 showed no protective effect against papain‐induced degeneration or LMHFV.
Jansen J, Figel F, Widmayer F, Vogt M, Ahrens M, Wilke H, Ignatius A, Haffner‐Luntzer M, Neidlinger‐Wilke C, Teixeira G.   +9 more
europepmc   +2 more sources

キカイテキソンショウノテイドノチガイガカルボニルストレスハツゲンニオヨボスエイキョウ [PDF]

, 2017
　 Low back pain is a significant public health problem worldwide. Intervertebral disc degeneration is most significant known risk factor for low back pain. Yet the mechanisms of degeneration remain relatively unknown.
サイモン タング, 日比野 至
core   +1 more source

Endogenous musculoskeletal tissue engineering - a focused perspective [PDF]

, 2012
Two major difficulties facing widespread clinical implementation of existing Tissue Engineering (TE) strategies for the treatment of musculoskeletal disorders are (1) the cost, space and time required for ex vivo culture of a patient’s autologous cells ...
Adam, Clayton
core   +2 more sources

A Meta‐Analysis of Cost‐Effectiveness in Cervical Degenerative Disc Disease Treated With Cervical Disc Arthroplasty Versus Anterior Cervical Discectomy and Fusion

Orthopaedic Surgery, EarlyView.
This meta‐analysis finds that anterior cervical discectomy and fusion (ACDF) has a lower initial cost, while cervical disc arthroplasty (CDA) demonstrates a lower risk of reoperation and DVT/PE. CDA's long‐term clinical benefits may offset its higher upfront expense.
Thomas Cho, Kriti Devgan, Nipun U. Jayatissa, Hossein Elgafy, Jiayong Liu   +4 more
wiley   +1 more source

Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. [PDF]

, 2016
The main pathogenesis of intervertebral disc (IVD) herniation involves disruption of the annulus fibrosus (AF) caused by ageing or excessive mechanical stress and the resulting prolapse of the nucleus pulposus.
Asahara, Hiroshi, Ichinose, Shizuko, Inagawa, Masayo, Inui, Masafumi, Ito, Yoshiaki, Kataoka, Kensuke, Kayama, Tomohiro, Lotz, Martin K, Masuda, Koichi, Mori, Masaki, Nakamichi, Ryo, Onizuka, Naoko, Ozaki, Toshifumi, Sakai, Daisuke, Suzuki, Hidetsugu   +14 more
core   +1 more source

O‐Arm Navigation Enhances Facet Preservation Without Compromising Clinical Outcomes in UBE Decompression for Radiographically Stable Adult Degenerative Scoliosis: A Single‐Center Comparative Study

Orthopaedic Surgery, EarlyView.
O‐arm navigation–assisted unilateral biportal endoscopic decompression achieves precise and sufficient neural decompression in stable adult degenerative scoliosis, enhancing facet preservation and reducing segmental motion changes while maintaining comparable symptomatic improvement to conventional fluoroscopy, demonstrating the value of navigation in ...
Yi Liu, Yiwei Xie, Zhibao Chen, Ruijun Xu, Haojie Chen, Xiaojian Ye, Jiangming Yu   +6 more
wiley   +1 more source

VEGF vascularization pathway in human intervertebral disc does not change during the disc degeneration process

BMC Research Notes, 2018
Objective During degeneration of the intervertebral disc ingrowth of blood vessels and nerves into the disc are associated with back pain. Vascular endothelial growth factors promote vasculogenesis by binding to the membrane vascular endothelial growth ...
Simona Capossela, Alessandro Bertolo, Kapila Gunasekera, Tobias Pötzel, Martin Baur, Jivko V. Stoyanov   +5 more
doaj   +1 more source

Keyhole Foraminotomy Combined With Unilateral Laminotomy for Bilateral Decompression Under Biportal Endoscopic Spinal Surgery for the Treatment of Mixed‐Type Cervical Spondylosis

Orthopaedic Surgery, EarlyView.
Under biportal endoscopic spine surgery, one‐stage decompression combining keyhole foraminotomy and unilateral laminotomy for bilateral decompression (ULBD) for mixed‐type cervical spondylopathy can achieve favorable clinical outcomes with minimal compromise of spinal stability.
Lejian Jiang, Xiaowei Jing, Xiaowen Qiu, Tianxin Wu, Danlei Zheng, Zhuolin Zhong, Yongzhi Jian, Qingfeng Hu   +7 more
wiley   +1 more source

Full Endoscopic Piecemeal Resection of Lumbar Ligamentum Flavum Cyst With Uniaxial Large Working Channel Spinal Endoscope: Technical Report and Case Series

Orthopaedic Surgery, EarlyView.
The formation of lumbar ligamentum flavum cyst (LLFC) represents one of the extremely rare etiologies of lumbar spinal stenosis. Owing to the rarity of such cases and the severe adhesion of LLFC to adjacent tissues, significant challenges are posed to surgical intervention.
Chunjian Gu, Jiaqi Zhang, Hongtao Xu, Xinchun Liu   +3 more
wiley   +1 more source