Results 161 to 170 of about 39,314 (264)

Neuroimmune Activation in a Goat Model of Intervertebral Disc Degeneration. [PDF]

Cells
Augustin JA, Burt KG, Barrett C, Fainor M, Orozco BS, Schaer TP, Smith HE, Mauck RL, Gullbrand SE.   +8 more
europepmc   +1 more source

The Role of Piezo 1 in the Study of Intervertebral Disc Degeneration: Phenotype, Mechanism and Treatment

Orthopaedic Surgery, Volume 18, Issue 5, Page 897-914, May 2026.
As the key mechanotransducer in IVDD, Piezo1 orchestrates region‐specific degeneration across NP (senescence/ECM dysregulation), AF (apoptosis), and CEP (inflammation). This review integrates mechanistic pathways and assesses multimodal therapeutic targeting (pharmacologic/genetic/nutritional) to restore disc homeostasis.
Guangye Li, Chaoqun Feng, Haoyun Huang, Junwen Deng, Fei Yang, Rigao Chen   +5 more
wiley   +1 more source

Role of Autophagy and Pyroptosis in Intervertebral Disc Degeneration

Journal of Inflammation Research
Zhiqiang Wang,* Xiaochun Li,* Pengfei Yu,* Yu Zhu, Feng Dai, Zhijia Ma, Xueqiang Shen, Hong Jiang, Jintao Liu Department of Orthopedic Surgery, Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, 215009, People’s
Wang Z, Li X, Yu P, Zhu Y, Dai F, Ma Z, Shen X, Jiang H, Liu J   +8 more
doaj  

Risk Factors and Clinical Significance for Retrolisthesis of Adjacent Segment After Transforaminal Lumbar Interbody Fusion

Orthopaedic Surgery, Volume 18, Issue 5, Page 958-966, May 2026.
Preoperative degeneration of endplates, facet joints, and paraspinal muscles, along with intraoperative facet violation, are key predictors of retrolisthesis after TLIF, leading to worse pain and functional outcomes. ABSTRACT Objective Adjacent segment retrolisthesis is a common yet frequently overlooked complication after lumbar fusion, which may lead
Zhongmao Xu, Qinghua Zhao, Bin Wang, Zezhang Zhu, Yong Qiu, Xu Sun   +5 more
wiley   +1 more source

Gas therapy: an innovative application for intervertebral disc degeneration. [PDF]

Med Gas Res
Cai L, Ru B, Ren H, Cai F, Zeng L, Yang J, Wang S, Zhang H, Li Y, Zhang L.   +9 more
europepmc   +1 more source

Single‐Segment Spinal Decompression and Fusion With Selective Nerve Root Block in Adult Degenerative Scoliosis: A Retrospective Comparative Study

Orthopaedic Surgery, Volume 18, Issue 5, Page 967-977, May 2026.
Single‐segment PLIF with preoperative SNRB achieves equivalent clinical outcomes to long‐segment fusion in adult degenerative scoliosis. This approach significantly reduces hospitalization duration and revision rates in appropriately selected patients.
Haoning Ma, Sizheng Zhan, Xiangsheng Tang, Ping Yi   +3 more
wiley   +1 more source

Immune Mechanisms and Pain in Intervertebral Disc Degeneration. [PDF]

J Inflamm Res
Cheng H, Wang L, Huang C, Yang Z, Wu H, Fang Z.   +5 more
europepmc   +1 more source

Clinical characterization of thoracolumbar and lumbar intervertebral disk extrusions in English Cocker Spaniels [PDF]

, 2016
Aikawa T, Braund KG, Brown NO, Caitlin E. Tzounos, Dewey CW, Goggin JE, Holger A. Volk, Mogensen MS, Ruddle TL, Steven De Decker, Thomas J.A. Cardy   +10 more
core   +2 more sources

Modified Spinous Process–Splitting Approach for Thoracolumbar Burst Fractures With Neurological Deficits: Technical Description and Preliminary Clinical Outcomes

Orthopaedic Surgery, Volume 18, Issue 5, Page 1085-1097, May 2026.
A modified spinous process–splitting approach provides effective midline decompression with preservation of posterior structures, resulting in marked neurological improvement, reduced pain, and substantial correction of canal encroachment in thoracolumbar burst fractures.
Kaixuan Chen, Yizhong Ma, Zihui Yang, Hongfeng Ruan, Guanyi Liu   +4 more
wiley   +1 more source

Molecular insights into Atorvastatin's role in delaying intervertebral disc degeneration. [PDF]

Front Cell Dev Biol
Li Y, Wang L, Wang X, Li K, Wang Q, Gao K, Zhang C, Lv C.   +7 more
europepmc   +1 more source