Results 181 to 190 of about 23,413 (232)

Compression suture: A method for simulating intervertebral disc degeneration in rats induced by excessive loading. [PDF]

Animal Model Exp Med
Liu X, Yang F, Xiao H, Duan Y, Kang X.
europepmc   +1 more source

HACE1 alleviates intervertebral disc degeneration by inhibiting ferroptosis in nucleus pulposus cells. [PDF]

Sci Rep
Xia J, Zhang W, Jiang Y, Li T, Dong H, Zhu L, Xia Q, Zhao Y, Yi J, Weng Z, Feng S, Xin Z.   +11 more
europepmc   +1 more source

Notch signaling-targeted biomimetic hydrogel constructs an anti-inflammatory "flood-control" system to alleviate pyroptosis for intervertebral disc degeneration treatment. [PDF]

Mater Today Bio
Zhang R, Zhang X, Guo J, Yang Y, Niu J, Shen H, Zheng Y, Wang J, Wang S, Ni L, Yang H, Shi Q.   +11 more
europepmc   +1 more source

Dasatinib and quercetin senolytic treatment delays early onset intervertebral disc degeneration in SM/J mice. [PDF]

Bone Res
Novais EJ, Ottone OK, Jagannath S, Akande EJ, Barve RA, Risbud MV.   +5 more
europepmc   +1 more source

Genetically predicted serum Pimelylcarnitine mediates the association between CD39+ secreting Treg cells and intervertebral disc degeneration. [PDF]

Medicine (Baltimore)
Li N, Shen C, Huang Z, Shao Z, Wu J, Hua D, Wang L.   +6 more
europepmc   +1 more source

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Intervertebral disc degeneration in the dog. Part 1: Anatomy and physiology of the intervertebral disc and characteristics of intervertebral disc degeneration

Veterinary Journal, 2013
Intervertebral disc (IVD) degeneration is common in dogs and can give rise to a number of diseases, such as IVD herniation, cervical spondylomyelopathy, and degenerative lumbosacral stenosis. Although there have been many reports and reviews on the clinical aspects of canine IVD disease, few reports have discussed and reviewed the process of IVD ...
Niklas Bergknut, Lucas A Smolders, Guy C M Grinwis   +2 more
exaly   +3 more sources

Genetics of Intervertebral Disc Degeneration

Current Osteoporosis Reports, 2023
Intervertebral disc degeneration is a contributor to chronic back pain. While a part of the natural aging process, early or rapid intervertebral disc degeneration is highly heritable. In this review, we summarize recent progress towards unraveling the genetics associated with this degenerative process.Use of large cohorts of patient data to conduct ...
David C. Ou-Yang, Christopher J. Kleck, Cheryl L. Ackert-Bicknell   +2 more
openaire   +2 more sources

Fundamentals of Intervertebral Disc Degeneration

World Neurosurgery, 2022
Lumbar disc degeneration is one of the leading causes of chronic low back pain. The degenerative cascade is often initiated by an imbalance between catabolic and anabolic processes in the intervertebral discs. As a consequence of extracellular matrix degradation, neoinnervation and neovascularization take place.
Sertac Kirnaz, Charisse Capadona, Taylor Wong, Jacob L. Goldberg, Branden Medary, Fabian Sommer, Lynn B. McGrath, Roger Härtl   +7 more
openaire   +2 more sources