Results 11 to 20 of about 37,526 (187)

Role of macrophage in intervertebral disc degeneration [PDF]

Bone Research
Intervertebral disc degeneration is a degenerative disease where inflammation and immune responses play significant roles. Macrophages, as key immune cells, critically regulate inflammation through polarization into different phenotypes. In recent years,
Yiming Dou, Yiming Zhang, Yang Liu, Xun Sun, Xinyu Liu, Bin Li, Qiang Yang   +6 more
doaj   +2 more sources

Notochord Cells in Intervertebral Disc Development and Degeneration [PDF]

Journal of Developmental Biology, 2016
The intervertebral disc is a complex structure responsible for flexibility, multi-axial motion, and load transmission throughout the spine. Importantly, degeneration of the intervertebral disc is thought to be an initiating factor for back pain. Due to a
Matthew R. McCann, Cheryle A. Séguin
doaj   +4 more sources

Exploring extracellular vesicles as novel therapeutic agents for intervertebral disc degeneration: delivery, applications, and mechanisms [PDF]

Stem Cell Research & Therapy
Intervertebral disc degeneration is a multifactorial degenerative disease that poses a significant threat to the health of the elderly population. Current treatments primarily focus on physical therapy, medication, and surgery to alleviate symptoms ...
Yuxin Jin, Ouqiang Wu, Zhihua Chen, Linjie Chen, Kai Zhang, Qizhu Chen, Haijun Tian, Xinzhou Wang, Morgan Jones, Kenny Yat Hong Kwan, Yan Michael Li, Pooyan Makvandi, Xiangyang Wang, Xiang Hai, Jun Zhang, Aimin Wu   +15 more
doaj   +2 more sources

Experimental intervertebral disc degeneration models [PDF]

, 2023
Intervertebral disc degeneration is a major health problem of close concern to both young and old. The problem is also growing as the global population ages.
İkinci̇ Keleş, Ayşe, Sönmez, Osman Fikret   +1 more
core   +1 more source

Clinical and magnetic resonance imaging characteristics of thoracolumbar intervertenral disk extrusions and protrusions in large breed dogs [PDF]

, 2002
It has recently been shown that the fat-derived hormone adiponectin has the ability to decrease hyperglycemia and to reverse insulin resistance. However, bacterially produced full-length adiponectin is functionally inactive. Here, we show that endogenous
Beltran, E, De Decker, S, Gomes, S A, Kenny, P J, Packer, R M A, Volk, H A   +5 more
core   +4 more sources

Equine cervical intervertebral disc degeneration is associated with location and MRI features [PDF]

, 2019
Morphology of the equine cervical intervertebral disc is different from that in humans and small companion animals and published imaging data are scarcely available.
Back, Willem, Bergmann, Wilhelmina, Nielen, Mirjam, van den Belt, Antoon-Jan M., Veraa, Stefanie, Vernooij, Hans, Wijnberg, Inge D.   +6 more
core   +1 more source

Evaluation of the influence of kyphosis and scoliosis on intervertebral disc extrusion in French bulldogs [PDF]

, 2018
Although thoracic vertebral malformations with kyphosis and scoliosis are often considered incidental findings on diagnostic imaging studies of screw-tailed brachycephalic breeds, they have been suggested to interfere with spinal biomechanics and ...
BA Brisson, CW Dewey, DR Westworth, E Schlensker, E Schlensker, F Wang, Gert ter Haar, GI Hristova, HG Parker, HK Chang, Holger A. Volk, IA Stokes, J Guevar, J Street, K Faller, LA Smolders, LM De Rycke, M Charalambous, MA Stone, Maria Claudia C. M. Inglez de Souza, MP Abdel, MS Mogensen, MS Mogensen, MS Yau, N Bergknut, ND Jeffery, O Epstein, P Bernstein, P Moissonnier, R Gutierrez-Quintana, RC Brink, Richard Ryan, RM Packer, Rowena M. A. Packer, S De Decker, SA Gomes, SD Decker, Steven De Decker, T Aikawa, T Aikawa   +39 more
core   +2 more sources

A novel magnetic resonance imaging postprocessing technique for the assessment of intervertebral disc degeneration-Correlation with histological grading in a rabbit disc degeneration model. [PDF]

, 2019
Introduction:Estimation of intervertebral disc degeneration on magnetic resonance imaging (MRI) is challenging. Qualitative schemes used in clinical practice correlate poorly with pain and quantitative techniques have not entered widespread clinical use.
Chamoli, Uphar, Diwan, Ashish D, Kato, Kenji, Masuda, Koichi, Miyazaki, Shingo, Sheldrick, Kyle   +5 more
core   +1 more source

Physical disruption of intervertebral disc promotes cell clustering and a degenerative phenotype [PDF]

, 2019
© 2019, The Author(s). To test the hypothesis that physical disruption of an intervertebral disc disturbs cell-matrix binding, leading to cell clustering and increased expression of matrix degrading enzymes that contribute towards degenerative disc cell ...
Adams, M.A., Claireaux, H., Dolan, T., Flower, L., Harding, I.J., Lama, P., Le Maitre, Christine   +6 more
core   +1 more source

Computer assisted characterization of cervical intervertebral disc degeneration in MRI [PDF]

, 2009
A texture-based pattern recognition system is proposed for the automatic characterization of cervical intervertebral disc degeneration from saggital magnetic resonance images of the spine.
Boniatis, I, Cavouras, D, Costaridou, L, Michopoulou, S, Panagiotopoulos, E, Panayiotakis, G   +5 more
core   +1 more source