Results 11 to 20 of about 25,892 (278)
Molecular Mechanisms of Intervertebral Disc Degeneration
Spine Surgery and Related Research, 2019 Intervertebral disc degeneration is a well-known cause of disability, the result of which includes neck and back pain with associated mobility limitations.
Sean Rider, Shuichi Mizuno, James Kang
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Genetic Therapy for Intervertebral Disc Degeneration [PDF]
International Journal of Molecular Sciences, 2021 Intervertebral disc (IVD) degeneration can cause chronic lower back pain (LBP), leading to disability. Despite significant advances in the treatment of discogenic LBP, the limitations of current treatments have sparked interest in biological approaches, including growth factor and stem cell injection, as new treatment options for patients with chronic ...
Eun Roh +7 more
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Treatment of Intervertebral Disc Degeneration
Orthopaedic Surgery, 2022 Intervertebral disc degeneration (IDD) causes a variety of signs and symptoms, such as low back pain (LBP), intervertebral disc herniation, and spinal stenosis, which contribute to high social and economic costs. IDD results from many factors, including genetic factors, aging, mechanical injury, malnutrition, and so on.
Jingguo Xin +5 more
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Macrophages and Intervertebral Disc Degeneration
International Journal of Molecular Sciences, 2023 The intervertebral disc (IVD) aids in motion and acts to absorb energy transmitted to the spine. With little inherent regenerative capacity, degeneration of the intervertebral disc results in intervertebral disc disease, which contributes to low back pain and significant disability in many individuals. Increasing evidence suggests that IVD degeneration
Jinsha Koroth +7 more
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Adrenoceptor Expression during Intervertebral Disc Degeneration [PDF]
International Journal of Molecular Sciences, 2020 Healthy and degenerating intervertebral discs (IVDs) are innervated by sympathetic nerves, however, adrenoceptor (AR) expression and functionality have never been investigated systematically. Therefore, AR gene expression was analyzed in both tissue and isolated cells from degenerated human IVDs.
Johannes Kupka +10 more
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Pathomechanism of intervertebral disc degeneration
JOR SPINE, 2020 AbstractIntervertebral disc degeneration (IDD) is the main contributor to low back pain, which is a leading cause of disability worldwide. Although substantial progress has been made in elucidating the molecular mechanisms of IDD, fundamental and long‐lasting treatments for IDD are still lacking.
Takeshi Oichi +4 more
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Prague Medical Report, 2022 Intervertebral disc degeneration is a pathological condition associated with the intervertebral disc and is related to functional alterations in the human body.
Nicole Barbosa Bettiol +9 more
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Effect of sIL-13Rα2-Fc on the progression of rat tail intervertebral disc degeneration
Journal of Orthopaedic Surgery and Research, 2019 Background The incidence of degenerative disc disease caused by intervertebral disc injury is increasing annually, seriously affecting the quality of life of patients and increasing the disease burden on society.
Xin Wang +7 more
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Cervical intervertebral disc degeneration and dizziness
World Journal of Clinical Cases, 2021 Clinical studies have found that patients withcervical degenerative disease are usually accompanied by dizziness. Anterior cervical surgery can eliminate not only chronic neck pain, cervical radiculopathy or myelopathy, but also dizziness. Immunohistochemical studies show that a large number of mechanoreceptors, especially Ruffini corpuscles, are ...
Liu, Tang-Hua +2 more
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SAGE Open Medicine, 2018 Intervertebral disc degeneration is a disease of the discs connecting adjoining vertebrae in which structural damage leads to loss of disc integrity.
Joseph Fernandez-Moure +8 more
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