Results 11 to 20 of about 38,647 (321)

Degeneration of the intervertebral disc. [PDF]

open access: goldArthritis research & therapy, 2003
The intervertebral disc is a cartilaginous structure that resembles articular cartilage in its biochemistry, but morphologically it is clearly different. It shows degenerative and ageing changes earlier than does any other connective tissue in the body.
Jill Urban, Sally Roberts
openalex   +5 more sources

Molecular Mechanisms of Intervertebral Disc Degeneration

open access: yesSpine Surgery and Related Research, 2019
Intervertebral disc degeneration is a well-known cause of disability, the result of which includes neck and back pain with associated mobility limitations.
Sean Rider, Shuichi Mizuno, James Kang
doaj   +5 more sources

Treatment of Intervertebral Disc Degeneration

open access: yesOrthopaedic Surgery, 2022
Intervertebral disc degeneration (IDD) causes a variety of signs and symptoms, such as low back pain (LBP), intervertebral disc herniation, and spinal stenosis, which contribute to high social and economic costs. IDD results from many factors, including genetic factors, aging, mechanical injury, malnutrition, and so on.
Jingguo Xin   +5 more
openaire   +3 more sources

Macrophages and Intervertebral Disc Degeneration

open access: yesInternational Journal of Molecular Sciences, 2023
The intervertebral disc (IVD) aids in motion and acts to absorb energy transmitted to the spine. With little inherent regenerative capacity, degeneration of the intervertebral disc results in intervertebral disc disease, which contributes to low back pain and significant disability in many individuals. Increasing evidence suggests that IVD degeneration
Jinsha Koroth   +7 more
openaire   +2 more sources

Genetic Therapy for Intervertebral Disc Degeneration [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Intervertebral disc (IVD) degeneration can cause chronic lower back pain (LBP), leading to disability. Despite significant advances in the treatment of discogenic LBP, the limitations of current treatments have sparked interest in biological approaches, including growth factor and stem cell injection, as new treatment options for patients with chronic ...
Eun Roh   +7 more
openaire   +3 more sources

Pathomechanism of intervertebral disc degeneration

open access: yesJOR SPINE, 2020
AbstractIntervertebral disc degeneration (IDD) is the main contributor to low back pain, which is a leading cause of disability worldwide. Although substantial progress has been made in elucidating the molecular mechanisms of IDD, fundamental and long‐lasting treatments for IDD are still lacking.
Sakae Tanaka   +5 more
openaire   +4 more sources

Equine cervical intervertebral disc degeneration is associated with location and MRI features [PDF]

open access: yes, 2019
Morphology of the equine cervical intervertebral disc is different from that in humans and small companion animals and published imaging data are scarcely available.
Back, Willem   +6 more
core   +1 more source

Intervertebral Disc Degeneration: Functional Analysis of Bite Force and Masseter and Temporal Muscles Thickness

open access: yesPrague Medical Report, 2022
Intervertebral disc degeneration is a pathological condition associated with the intervertebral disc and is related to functional alterations in the human body.
Nicole Barbosa Bettiol   +9 more
doaj   +1 more source

Physical disruption of intervertebral disc promotes cell clustering and a degenerative phenotype [PDF]

open access: yes, 2019
© 2019, The Author(s). To test the hypothesis that physical disruption of an intervertebral disc disturbs cell-matrix binding, leading to cell clustering and increased expression of matrix degrading enzymes that contribute towards degenerative disc cell ...
Adams, M.A.   +6 more
core   +1 more source

A novel magnetic resonance imaging postprocessing technique for the assessment of intervertebral disc degeneration-Correlation with histological grading in a rabbit disc degeneration model. [PDF]

open access: yes, 2019
Introduction:Estimation of intervertebral disc degeneration on magnetic resonance imaging (MRI) is challenging. Qualitative schemes used in clinical practice correlate poorly with pain and quantitative techniques have not entered widespread clinical use.
Chamoli, Uphar   +5 more
core   +1 more source

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