Results 241 to 250 of about 81,428 (351)

Excessive reactive oxygen species are therapeutic targets for intervertebral disc degeneration [PDF]

, 2015
Satoshi Suzuki, Nobuyuki Fujita, Naobumi Hosogane, Kota Watanabe, Ken Ishii, Yoshiaki Toyama, Keiyo Takubo, Keisuke Horiuchi, Takeshi Miyamoto, Masaya Nakamura, Morio Matsumoto   +10 more
openalex   +1 more source

Identification and Validation of Circadian Rhythm‐Related Genes Involved in Intervertebral Disc Degeneration and Analysis of Immune Cell Infiltration via Machine Learning

JOR SPINE, Volume 8, Issue 2, June 2025.
Within this manuscript, bioinformatics and experimental methods are used to explore the role of circadian rhythm and immunity in Intervertebral Disc Degeneration (IVDD). CCND1, FOXO1, FRMD8, NTRK2, PRRT1, and TFPI were successfully demonstrated to be hub rhythm‐related genes in the process of IVDD together with immunity.
Yongbo Zhang, Liuyang Chen, Sheng Yang, Rui Dai, Hua Sun, Liang Zhang   +5 more
wiley   +1 more source

Mitochondrial quality control: the real dawn of intervertebral disc degeneration? [PDF]

J Transl Med
Qiu B, Xie X, Xi Y.
europepmc   +1 more source

Intervertebral disc degeneration therapies in human [PDF]

, 2015
Stephen M. Richardson
openalex   +1 more source

Heat Shock Strengthens the Protective Potential of MSCs in Liver Injury by Promoting EV Release Through Upregulated Autophagosome Formation

Journal of Extracellular Vesicles, Volume 14, Issue 5, May 2025.
ABSTRACT Mesenchymal stem cell‐derived extracellular vesicles (MSC‐EVs) show powerful potential in the treatment of multiple diseases. However, the low yield of MSC‐EVs severely restricts their clinical application. Here, heat shock (HS), a moderate external stimulus, can enhance EVs release of MSCs by upregulating autophagosome formation ...
Tingting Wang, Yihang Gong, Huizhu Lin, Xuejiao Li, Jinliang Liang, Xiaofeng Yuan, Cuiping Li, Zhongying Hu, Haitian Chen, Jiaqi Xiao, Jiebin Zhang, Yasong Liu, Xijing Yan, Chenhao Jiang, Jia Yao, Qi Zhang, Rong Li, Jun Zheng   +17 more
wiley   +1 more source

An enzyme-proof glycan glue for extracellular matrix to ameliorate intervertebral disc degeneration. [PDF]

Nat Commun
Liu Y, Chao T, Li Y, Peng P, Ge G, Geng D, Dong L, Wang C.   +7 more
europepmc   +1 more source

Vitamin D Receptor Gene and Aggrecan Gene Polymorphisms and the Risk of Intervertebral Disc Degeneration — A Meta-Analysis

, 2012
Ge Xu, Qiang Mei, Daijun Zhou, Jinlin Wu, Han Luo   +4 more
openalex   +2 more sources

Progranulin Knockout Accelerates Intervertebral Disc Degeneration in Aging Mice [PDF]

, 2015
Yunpeng Zhao, Qingyun Tian, Ben Liu, Jason M. Cuéllar, Brendon Richbourgh, Tanghong Jia, Liu C   +6 more
openalex   +1 more source

Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application

MedComm, Volume 6, Issue 5, May 2025.
Molecular hydrogen, delivered through inhalation, hydrogen‐rich water, or hydrogen solution injection, reduces oxidative stress, regulates immune responses, facilitates cell repair, and alleviates inflammatory bowel disease (IBD) and intestinal injury.
Jiayi Jin, Lijun Yue, Maoru Du, Feng Geng, Xue Gao, Yuming Zhou, Qianqian Lu, Xiaohong Pan   +7 more
wiley   +1 more source

Nanotechnology-Enhanced Pharmacotherapy for Intervertebral Disc Degeneration Treatment. [PDF]

Int J Nanomedicine
Shi S, Ou X, Liu C, Li R, Zheng Q, Hu L.
europepmc   +1 more source