Results 21 to 30 of about 82,752 (303)
The Proteolysis of ECM in Intervertebral Disc Degeneration
International Journal of Molecular Sciences, 2022 Intervertebral disc (IVD) degeneration (IDD) is a pathological process that commonly occurs throughout the human life span and is a major cause of lower back pain. Better elucidation of the molecular mechanisms involved in disc degeneration could provide
Huaizhen Liang +5 more
semanticscholar +1 more source
陆军军医大学学报, 2023 Objective To explore the role and possible mechanism of lysyl oxidase (LOX) in age-related degeneration of intervertebral disc. Methods Six SD rats, aged of 2, 8 and 20 months respectively, were subjected, and then underwent intervertebral disc MRI and X-
LI Jianmin +3 more
doaj +1 more source
The Nrf2 antioxidant defense system in intervertebral disc degeneration: Molecular insights
Experimental and Molecular Medicine, 2022 Intervertebral disc degeneration (IDD) is a common degenerative musculoskeletal disorder and is recognized as a major contributor to discogenic lower back pain.
Qian Xiang +4 more
semanticscholar +1 more source
Advanced Healthcare Materials, 2022 Intervertebral disc degeneration is a common cause of discogenic low back pain resulting in significant disability. Current conservative or surgical intervention treatments do not reverse the underlying disc degeneration or regenerate the disc ...
I. Isa +5 more
semanticscholar +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Intervertebral disc (IVD) degeneration (IDD) is the most universal pathogenesis of low back pain (LBP), a prevalent and costly medical problem across the world.
Zongtai Liu, Changfeng Fu
doaj +1 more source
WTAP-mediated m6A modification of lncRNA NORAD promotes intervertebral disc degeneration
Nature Communications, 2022 N6-methyladenosine (m6A) is the most prevalent RNA modification at the posttranscriptional level and involved in various diseases and cellular processes.
Gaocai Li +14 more
semanticscholar +1 more source
Association Between Sarcopenia and the Long-Term Risk of Intervertebral Disc Degeneration. [PDF]
J Cachexia Sarcopenia MuscleABSTRACT Background Sarcopenia and intervertebral disc degeneration (IDD) are both highly prevalent among the elderly and have a substantial impact on their quality of life. However, the association between sarcopenia and IDD remains unclear. This study aimed to investigate whether sarcopenia is independently associated with an increased risk of IDD in
Chen J +13 more
europepmc +2 more sources
The Role of Oxidative Stress in Intervertebral Disc Degeneration
Oxidative Medicine and Cellular Longevity, 2022 Intervertebral disc degeneration is a very common type of degenerative disease causing severe socioeconomic impact, as well as a major cause of discogenic low back pain and herniated discs, placing a heavy burden on patients and the clinicians who treat ...
Guoshuai Cao +7 more
semanticscholar +1 more source
Equine cervical intervertebral disc degeneration is associated with location and MRI features [PDF]
, 2019 Morphology of the equine cervical intervertebral disc is different from that in humans and small companion animals and published imaging data are scarcely available.
Back, Willem +6 more
core +1 more source
Deep learning-based high-accuracy quantitation for lumbar intervertebral disc degeneration from MRI
Nature Communications, 2022 To help doctors and patients evaluate lumbar intervertebral disc degeneration (IVDD) accurately and efficiently, we propose a segmentation network and a quantitation method for IVDD from T2MRI.
Hua-Dong Zheng +12 more
semanticscholar +1 more source