Results 31 to 40 of about 81,428 (351)

Clinical and magnetic resonance imaging characteristics of thoracolumbar intervertenral disk extrusions and protrusions in large breed dogs [PDF]

, 2002
It has recently been shown that the fat-derived hormone adiponectin has the ability to decrease hyperglycemia and to reverse insulin resistance. However, bacterially produced full-length adiponectin is functionally inactive. Here, we show that endogenous
Beltran, E, De Decker, S, Gomes, S A, Kenny, P J, Packer, R M A, Volk, H A   +5 more
core   +4 more sources

Fibrotic and inflammatory characteristics of epidural fat adjacent to the ossification area in patients with ossification of the ligament flavum

JOR SPINE, Volume 5, Issue 4, December 2022., 2022
We observed the histological and inflammatory characteristics of epidural fat (EF) adjacent to the ossification area in patients with ossification of the thoracic ligament flavum (TOLF) and provide a preliminary basis for investigating the impact of EF on OLF. Morphologically, EF exhibits no significant differences between the TOLF and non‐TOLF groups,
Xinyu Dou, Tianli Mao, Yunlong Ma, Fei Jia, Yu Liu, Xiaoguang Liu   +5 more
wiley   +1 more source

Controversies in spine research: Organ culture versus in vivo models for studies of the intervertebral disc

JOR SPINE, Volume 5, Issue 4, December 2022., 2022
Abstract Intervertebral disc degeneration is a common cause of low back pain, the leading cause of disability worldwide. Appropriate preclinical models for intervertebral disc research are essential to achieving a better understanding of underlying pathophysiology and for the development, evaluation, and translation of more effective treatments.
Shirley N. Tang, Andres F. Bonilla, Nadeen O. Chahine, Aimee C. Colbath, Jeremiah T. Easley, Sibylle Grad, Lisbet Haglund, Christine L. Le Maitre, Victor Leung, Annette M. McCoy, Devina Purmessur, Simon Y. Tang, Stephan Zeiter, Lachlan J. Smith   +13 more
wiley   +1 more source

Development and degeneration of the intervertebral discs

Molecular Medicine Today, 1995
The intervertebral discs undergo profound changes in structure and composition during development and aging. They also degenerate much earlier than other cartilaginous tissues, and in severe cases may lose function completely. The reasons for this early degeneration are unknown, but external factors, such as mechanical overload on the spine, or smoking,
Urban, J, Roberts, S
openaire   +3 more sources

The role of ferroptosis in intervertebral disc degeneration

Frontiers in Cell and Developmental Biology, 2023
Nucleus pulposus, annulus fibrosus, and cartilage endplate constitute an avascular intervertebral disc (IVD), which is crucial for spinal and intervertebral joint mobility. As one of the most widespread health issues worldwide, intervertebral disc degeneration (IVDD) is recognized as a key contributor to back and neck discomfort.
Chunyang Fan, Genglei Chu, Zilin Yu, Zhongwei Ji, Zhongwei Ji, Fanchen Kong, Lingye Yao, Jiale Wang, Dechun Geng, Xiexing Wu, Haiqing Mao   +10 more
openaire   +3 more sources

Prediction of subsequent osteoporotic vertebral compression fracture on CT radiography via deep learning

VIEW, Volume 3, Issue 6, December 2022., 2022
This study analyzed the characteristics of patients with twice osteoporotic vertebral compression fracture (OVCF), designed and established a deep‐based prediction model of subsequent OVCF, which could predict subsequent OVCF in using computed tomography (CT) images.
Xiao Hu, Yanjing Zhu, Yadong Qian, Ruiqi Huang, Shuai Yin, Zhili Zeng, Ning Xie, Bin Ma, Yan Yu, Qing Zhao, Zhourui Wu, Jianjie Wang, Wei Xu, Yilong Ren, Chen Li, Rongrong Zhu, Liming Cheng   +16 more
wiley   +1 more source

Development of a Decellularized Hydrogel Composite and its Application in a Novel Model of Disc-associated Low Back Pain in Female Sprague Dawley Rats [PDF]

, 2022
Chronic low back pain is a global socioeconomic crisis compounded by an absence of reliable, curative treatments. The predominant pathology associated with chronic low back pain is degeneration of intervertebral discs in the lumbar spine.
Lillyman, David
core   +1 more source

Cervical intervertebral disc degeneration and dizziness

World Journal of Clinical Cases, 2021
Clinical studies have found that patients withcervical degenerative disease are usually accompanied by dizziness. Anterior cervical surgery can eliminate not only chronic neck pain, cervical radiculopathy or myelopathy, but also dizziness. Immunohistochemical studies show that a large number of mechanoreceptors, especially Ruffini corpuscles, are ...
Bao-Gan Peng, Yan-Qing Liu, Tang-Hua Liu
openaire   +3 more sources

Microstructure analysis method for evaluating degenerated intervertebral disc tissue [PDF]

, 2017
Degeneration of intervertebral disc (IVD) tissue is characterized by several structural changes that result in variations in disc physiology and loss of biomechanical function.
Adams, Andrea Friedmann, Andreas Heilmann, Antoniou, Buckwalter, Carlson, Christopher Ludtka, Chung, Ciapetti, Colombier, Ding, Donath, Duance, Felix Goehre, Ford, Friedmann, Gruber, Gruber, Hadjipavlou, Hans-Joerg Meisel, Hristova, Hübner, Johnson, Kepler, Kobayashi, Le Maitre, Lee, Majeed, Pai, Pfirrmann, Postacchini, Raj, Roberts, Roberts, Schirmer, Sharp, Siemionow, Singh, Smith, Stefan Schwan, Thomas Mendel, Tomaszewski, Trout, Urban, Vergroesen, Vernon-Roberts, Whatley, Willbold, Woods, Yerramalli, Zhang, Zhao   +51 more
core   +1 more source

Effect of sIL-13Rα2-Fc on the progression of rat tail intervertebral disc degeneration

Journal of Orthopaedic Surgery and Research, 2019
Background The incidence of degenerative disc disease caused by intervertebral disc injury is increasing annually, seriously affecting the quality of life of patients and increasing the disease burden on society.
Xin Wang, Junhao Sun, Jianshi Tan, Pengzhong Fang, Jinlei Chen, Wen Yuan, Huajiang Chen, Yang Liu   +7 more
doaj   +1 more source