Results 81 to 90 of about 25,892 (278)

Clinical Characteristics and a New Classification System of Mono‐Segmental Thoracic and Lumbar Nonfusion in Patients With Ankylosing Spondylitis

Orthopaedic Surgery, EarlyView.
In regard to the mono‐segmental thoracic and lumbar nonfusion in patients with ankylosing spondylitis, we built a new classification system based on CT and MRI data and describe its clinical distribution characteristics and occurrence risk factors for the first time. ABSTRACT Study Design Retrospective cohort study.
Bingchuan Liu, Zhengguang Wang, Fang Zhou, Yun Tian, Zhishan Zhang   +4 more
wiley   +1 more source

Polyethylene microplastics promote nucleus pulposus cell senescence by inducing oxidative stress via TLR4/NOX2 axis

Ecotoxicology and Environmental Safety
This study aimed to detect and characterize microplastics in intervertebral disc and investigate their effects and molecular mechanism on intervertebral disc degeneration.
Weilin Zhang, Zhencong Li, Zhongwei Wang, Kuize Liu, Shengbang Huang, Jinguo Liang, Zhiwen Dai, Weixiong Guo, Chao Mao, Siyuan Chen, Jinsong Wei   +10 more
doaj   +1 more source

Systemic clearance of p16^INK4a‐positive senescent cells mitigates age‐associated intervertebral disc degeneration [PDF]

, 2019
Prashanti Patil, Qing Dong, Dong Wang, Jianhui Chang, Christopher D. Wiley, Marco Demaria, Joon Lee, James D. Kang, Laura J. Niedernhofer, Paul D. Robbins, Gwendolyn Sowa, Judith Campisi, Daohong Zhou, Nam Vo   +13 more
openalex   +1 more source

Additional file 6 of Integrated transcriptome and proteome analyses identify novel regulatory network of nucleus pulposus cells in intervertebral disc degeneration

, 2021
Xu Chen, Shengchang Luo, Leixin Wei, Huiqiao Wu, Wei Gu, Wenchao Zhou, Baifeng Sun, Bo Hu, Hongyu Zhou, Yang Liu, Huajiang Chen, Xiaojian Ye, Wen Yuan   +12 more
openalex   +1 more source

Exosomal MATN3 of Urine‐Derived Stem Cells Ameliorates Intervertebral Disc Degeneration by Antisenescence Effects and Promotes NPC Proliferation and ECM Synthesis by Activating TGF‐β [PDF]

, 2021
Zhu Guo, Weiliang Su, RongYao Zhou, Guo-qing Zhang, Shuai Yang, Xiaolin Wu, Chensheng Qiu, Wenbin Cong, Nana Shen, Jianwei Guo, Chang Liu, Shang‐You Yang, Dongming Xing, Yan Wang, Bohua Chen, Hongfei Xiang   +15 more
openalex   +1 more source

Is Pedicle‐Screw Internal Fixation With Two Small Incisions Superior to Traditional MI‐TLIF With Four Incisions? Preliminary Follow‐Up Results

Orthopaedic Surgery, EarlyView.
A two‐incision MI‐TLIF showed comparable outcomes to the traditional four‐incision approach in single‐level patients. Excessive pursuit of smaller or fewer incisions demonstrated no significant short‐term advantage. Reduced exposure may still help minimize wound complications in vulnerable groups, warranting further targeted follow‐up.
Yueh‐Ying Hsieh, Lien‐Chen Wu, Fon‐Yih Tsuang, Chia‐Hsien Chen, Chang‐Jung Chiang   +4 more
wiley   +1 more source

Leptin and the intervertebral disc: a biochemical link exists between obesity, intervertebral disc degeneration and low back pain—an in vitro study in a bovine model [PDF]

, 2018
Anand Segar, Jeremy Fairbank, Jill Urban
openalex   +1 more source

The Effect of Unilateral Laminotomy Decompression in the Prevention of Adjacent Spinal Canal Stenosis During Lumbar Fusion

Orthopaedic Surgery, EarlyView.
Lumbar fusion can cause adjacent vertebral diseases, about 50% of which is spinal stenosis. Our retrospective cohort study demonstrated that concurrent laminotomy decompression of proximal adjacent vertebrae during primary lumbar fusion surgery significantly reduces the incidence of adjacent segment stenosis at 1‐year follow‐up.
Yan Ma, Yufei Liu, Jun Ma, Teng Yao, Chenkai Wu, Jianjun Ma   +5 more
wiley   +1 more source

Zhiqiao Gancao decoction regulated JAK2/STAT3/ macrophage M1 polarization to ameliorate intervertebral disc degeneration

Heliyon
Background: Zhiqiao Gancao decoction (ZQGCD) was created by Professor Gong Zhengfeng, a renowned Chinese medicine expert. Clinical studies have shown its efficacy in alleviating pain and enhancing lumbar function in intervertebral disc degeneration (IDD)
Zeling Huang, Xiaofeng Shen, Hua Chen, Zaishi Zhu, Binjie Lu, Long Zhang, Yujiang Liu, Yuwei Li, Bo Xu   +8 more
doaj   +1 more source

Analysis of Risk Factors for Adjacent Segment Disease After Lumbar Facet Joint Fusion

Orthopaedic Surgery, EarlyView.
This schematic illustrates a novel posterior lumbar fusion procedure targeting L4–L5 segments, with emphasis on the position of split bone and the precise site of bone grafting. Featuring “active generation + real‐time verification” and intact posterior tension band, this technique achieves precise segmental lordosis restoration with enhanced ...
Haibiao Qin, Jinglong Yan, Guangxi Wang, Hui Chi, Xu Zhang, Pengyu Kong, Chunyang Xi   +6 more
wiley   +1 more source