Results 81 to 90 of about 37,526 (187)

Serglycin secreted by late-stage nucleus pulposus cells is a biomarker of intervertebral disc degeneration

Nature Communications
Intervertebral disc degeneration is a natural process during aging and a leading cause of lower back pain. Here, we generate a comprehensive atlas of nucleus pulposus cells using single-cell RNA-seq analysis of human nucleus pulposus tissues (three males
Fan Chen, Linchuan Lei, Shunlun Chen, Zhuoyang Zhao, Yuming Huang, Guowei Jiang, Xingyu Guo, Zemin Li, Zhaomin Zheng, Jianru Wang   +9 more
doaj   +1 more source

Is interleukin-1 a good target for therapeutic intervention in intervertebral disc degeneration: lessons from the osteoarthritic experience [PDF]

, 2007
Philippe Goupille, Denis Mulleman, Xavier Chevalier   +2 more
openalex   +1 more source

Age-related degeneration of lumbar intervertebral discs in rabbits revealed by deuterium oxide-assisted MRI [PDF]

, 2008
Vyl Leung, Siu-Chun Hung, L.-C. Li, EX Wu, Keith D. K. Luk, Danny Chan, Kmc Cheung   +6 more
openalex   +1 more source

Innovating intervertebral disc degeneration therapy: Harnessing the power of extracellular vesicles

Journal of Orthopaedic Translation
Intervertebral disc degeneration is the leading cause of low back pain, imposing significant burdens on patients, societies, and economies. Advancements in regenerative medicine have spotlighted extracellular vesicles as promising nanoparticles for ...
Shanfeng Chen, Yiming Dou, Yiming Zhang, Xun Sun, Xinyu Liu, Qiang Yang   +5 more
doaj  

The Nucleus of the Intervertebral Disc from Development to Degeneration

, 2000
J Urban, Sally Roberts, James R. Ralphs
openalex   +1 more source

Intradiscal transplantation of synovial mesenchymal stem cells prevents intervertebral disc degeneration through suppression of matrix metalloproteinase-related genes in nucleus pulposus cells in rabbits [PDF]

, 2010
Takashi Miyamoto, Takeshi Muneta, Takashi Tabuchi, Kenji Matsumoto, Hirohisa Saito, Kunikazu Tsuji, Ichiro Sekiya   +6 more
openalex   +1 more source

Seeing the unseen: The role of bioimaging techniques for the diagnostic interventions in intervertebral disc degeneration

Bone Reports
Intervertebral Disc Degeneration is a pathophysiological condition that primarily affects the spinal discs, causing back pain and neurological deficits.
Gyanoday Tripathi, Lahanya Guha, Hemant Kumar   +2 more
doaj  

Immunolocalization of Growth Factors in Degeneration of Cervical Intervertebral Discs

, 2002
Yuki Ida, Tetsuya Morimoto, Rinsei Tei, Takuo Inui, Hiroyuki Nakase, Toshisuke Sakaki   +5 more
openalex   +2 more sources

Interleukin‐1β induces angiogenesis and innervation in human intervertebral disc degeneration [PDF]

, 2010
Jae Man Lee, Ji Ye Song, Minjung Baek, Hye‐Young Jung, Haeyoun Kang, In Bo Han, Young Do Kwon, Dong Eun Shin   +7 more
openalex   +1 more source

In vivo 3.0‐tesla magnetic resonance T_1ρ and T₂ relaxation mapping in subjects with intervertebral disc degeneration and clinical symptoms [PDF]

, 2010
Gabrielle Blumenkrantz, Jin Zuo, Xiaojuan Li, John Kornak, Thomas M. Link, Sharmila Majumdar   +5 more
openalex   +1 more source