Results 101 to 110 of about 21,214 (287)

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney   +4 more
wiley   +1 more source

Evaluation of Partial Volume Correction Techniques for Sodium MRI of the Achilles Tendon

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 4, Page 2180-2193, April 2026.
ABSTRACT Purpose To evaluate partial volume correction (PVC) techniques for sodium MRI of the Achilles tendon in situ and in vivo. Methods Five PVC methods were evaluated including a volume ratio of the proton and sodium segmentations (PSSR), a modified least trimmed square (3D‐mLTS) linear regression, a geometric transfer matrix (GTM) approach, a ...
Rika Möller   +10 more
wiley   +1 more source

A wireless acquisition system for monitoring the influence of loads on vertebral column behaviour [PDF]

open access: yes, 2008
This paper presents a wireless acquisition module (WAM). This allows the monitoring of heavy loads influence on vertebral column’s behaviour. Each module makes the electromyography (EMG), to measure the electric potentials on the iliocostalis and ...
Carmo, João, Ribeiro, J.E.
core  

Complex Mechanical Loading and Pro‐Inflammatory Cytokines in Intervertebral Disc Degeneration

open access: yesJOR SPINE, Volume 9, Issue 1, March 2026.
This study investigated the combined effects of dynamic compression and torsion with major pro‐catabolic cytokine interleukin‐1 beta (IL‐1β) and its inhibitor: interleukin‐1 receptor antagonist (IL‐1Ra), on bovine IVD in an ex vivo organ culture system and further evaluated the mechanical effects using a subject‐personalized finite element model based ...
Katherine B. Crump   +8 more
wiley   +1 more source

Influence of the Intervertebral Disc Microenvironment on Matrix Synthesis and Metabolism in Goat Nucleus Pulposus Cells

open access: yesJOR SPINE, Volume 9, Issue 1, March 2026.
Goat nucleus pulposus cells cultured under clinically relevant oxygen, glucose, pH, and osmolarity revealed pH to have the most influential impact on viability and glycosaminoglycan synthesis. Interactions between factors showed that disc cell behavior is shaped by the microenvironment, highlighting its importance in regenerative therapy design for the
Niamh Wilson   +5 more
wiley   +1 more source

Cisto intraespinal em comunicação com o disco intervertebral na coluna lombar: relato de um caso e revisão da literatura Quiste intraespinhal en comunicación con el disco intervertebral em la columna lumbar: reporte de caso y revisión de la literatura Intraspinal cyst communicating with the intervertebral disk in the lumbar spine: case report and literature review

open access: yesColuna/Columna, 2012
A hérnia discal lombar é causa importante bem como a mais freqüente de lombalgia e ciática. Muitos dos casos podem prontamente ser diagnosticados através do simples exame semiológico.
Mauricio Marteleto Filho   +7 more
doaj  

Interacting Active Rectangles for Estimation of Intervertebral Disk Orientation [PDF]

open access: yes, 2008
This paper presents a fast and efficient method to determine intervertebral disk orientation in a magnetic resonance (MR) image of the spine. The algorithm originates from active contour theory and enforces a shape constraint to avoid leaks through weak ...
Abufadel, A.   +4 more
core  

Biomechanical Effects of Different Approaches and Titanium Mesh in Combined Anterior Cervical Corpectomy Decompression and Fusion: A Finite Element Study

open access: yesEngineering Reports, Volume 8, Issue 2, February 2026.
Equivalent stress cloud maps of cervical spine flexion movement after four anterior approach methods. (a) VBSP‐S method. (b) AVBSP‐C method. (c) APSP‐S method. (d) APSP‐C method. ACCF biomechanics depend on fixation (AVBSP/APSP) and mesh shape (linear/curved). Adjacent disc sensitivity varies. Fixation choice affects titanium mesh stress.
Dan Li, Ke Wang, Chao Dong, Lingyi Deng
wiley   +1 more source

Synaptic Vesicle Glycoprotein 2A Suppresses Amyloidogenesis Beyond Its Synaptic Role: A Novel Mechanism Disrupting BACE1 Binding and Altering APP Localization

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
Synaptic vesicle glycoprotein 2A, the newly identified APP‐binding protein, reduces amyloid‐β plaque deposition in Alzheimer's disease by suppressing the amyloidogenic pathway through inhibition of BACE1‐APP interaction and alteration of APP endosomal‐lysosomal localization.
Xiaoling Wang   +11 more
wiley   +1 more source

Correlation of radiographic and MRI parameters to morphological and biochemical assessment of intervertebral disc degeneration [PDF]

open access: yes, 2018
Degenerative disc disease (DDD) is a common finding in MRI scans and X-rays. However, their correlation to morphological and biochemical changes is not well established.
Alini, Mauro   +4 more
core  

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