In vitro demonstration of intestinal absorption mechanisms of different sugars using 3d organotypic tissues in a fluidic device [PDF]
Intestinal permeability is crucial in regulating the bioavailability and, consequently, the biological effects of drugs and compounds. However, systematic and quantitative studies of the absorption of molecules are quite limited due to a lack of reliable
Aiello, M.+8 more
core +1 more source
Abdominal synthetic CT reconstruction with intensity projection prior for MRI-only adaptive radiotherapy [PDF]
An MRI-only adaptive radiotherapy (ART) workflow is desirable for managing interfractional changes in anatomy, but producing synthetic CT (sCT) data through paired data-driven deep learning (DL) for abdominal dose calculations remains a challenge due to the highly variable presence of intestinal gas.
arxiv +1 more source
Evaluacion de un producto a base de aceite esencial de oregano sobre la integridad intestinal, la capacidad de absorcion de nutrientes y el comportamiento productivo de pollos de carne [PDF]
Eight experiments were conducted to test an oregano-essential-oil-based product (PRO) on performance, gut health, and nutrient absorption capacity in broilers. The first three, up to 14d and without specific challenges, tested the effects on intestinal histology, skeletal integrity, and growth.
arxiv
Intestinal lipid absorption [PDF]
Our knowledge of the uptake and transport of dietary fat and fat-soluble vitamins has advanced considerably. Researchers have identified several new mechanisms by which lipids are taken up by enterocytes and packaged as chylomicrons for export into the lymphatic system or clarified the actions of mechanisms previously known to participate in these ...
M. Mahmood Hussain, Jahangir Iqbal
openaire +3 more sources
Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption [PDF]
Oral absorption of compounds depends on many physiological, physiochemical and formulation factors. Two important properties that govern oral absorption are in vitro permeability and solubility, which are commonly used as indicators of human intestinal ...
Alex A. Freitas+83 more
core +2 more sources
Paracellular Absorption: A Bat Breaks the Mammal Paradigm [PDF]
Bats tend to have less intestinal tissue than comparably sized nonflying mammals. The corresponding reduction in intestinal volume and hence mass of digesta carried is advantageous because the costs of flight increase with load carried and because take ...
AN Makanya+73 more
core +10 more sources
Postprandial morphological response of the intestinal epithelium of the Burmese python (Python molurus) [PDF]
The postprandial morphological changes of the intestinal epithelium of Burmese pythons were examined using fasting pythons and at eight time points after feeding. In fasting pythons, tightly packed enterocytes possess very short microvilli and are arranged in a pseudostratified fashion.
arxiv +1 more source
Intestinal Absorption of Bile Salts
Bile acids are secreted from the liver into the duodenum where they aid in the digestion and absorption of dietary lipids. Absorption of bile acids occurs through both ionic and nonionic diffusion in the jejunum and colon and through an active sodium ion-
Karen Madsen
doaj +1 more source
Research Progress in In Vitro Intestinal Cell Models and Their Applications in Evaluating Anthocyanin Absorption and Transport [PDF]
Anthocyanins are ubiquitous in plants, and many studies indicate that they possess diverse biological activities depending on their bioaccessibility and bioavailability.
ZHONG Hao, XU Jie, CHEN Ling, LIU Xiaofeng, GUAN Rongfa
doaj +1 more source
Colonic Absorption of Antiepileptic Agents [PDF]
Purpose: To evaluate a canine intestinal access-port model to study colonic absorption of drugs. The antiepileptic drugs phenytoin and gabapentin were chosen to study absorption of a lipophilic and hydrophilic compound, respectively. Methods: Drug plasma
Fleisher, David+2 more
core +1 more source