Results 91 to 100 of about 357,808 (308)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Research Progress in Lactoferrin’s Role in Alleviating Intestinal Barrier Dysfunction [PDF]

Shipin Kexue
The intestinal barrier plays a crucial role in maintaining homeostasis in the body. When the intestinal mucosa is damaged, the tight junctions between intestinal cells are disrupted, and the intestinal flora becomes imbalanced, a variety of diseases can ...
LI Yi, REN Xinxin, WANG Qin, HE Xiaoyun
doaj   +1 more source

Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium [PDF]

, 2017
Adaptive cellular responses are often required during wound repair. Following disruption of the intestinal epithelium, wound‐associated epithelial (WAE) cells form the initial barrier over the wound.
Lai, Chin-Wen, Malvin, Nicole P, Miyoshi, Hiroyuki, Ryu, Stacy H, Sonnek, Naomi M, Stappenbeck, Thaddeus S, VanDussen, Kelli L, Wang, Yi   +7 more
core   +2 more sources

Role of subclinical gut inflammation in the pathogenesis of spondyloarthritis [PDF]

, 2018
Subclinical gut inflammation occurring in patients affected by spondyloarthritis (SpA) is correlated with the severity of spine inflammation. Several evidences indicate that dysbiosis occurs in SpA, and that may modulate intestinal permeability and ...
Ciccia F., Ferrante A., Guggino G., Rizzo A.   +3 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Intestinal permeability measurements: general aspects and possible pitfalls

Nutrición Hospitalaria, 2014
Introduction: Disturbances of the gut barrier function have been related to a variety of diseases, including intestinal and extra-intestinal diseases. The intestinal permeability tests are considered useful tools for evaluating disease severity and to ...
Tatiana Fiche Salles Teixeira, Ana Paula Boroni Moreira, Nilian Carla Silva Souza, Rafael Frias, Maria do Carmo Gouveia Peluzio   +4 more
doaj   +1 more source

Differences in intestinal size, structure, and function contributing to feed efficiency in broiler chickens reared at geographically distant locations [PDF]

, 2019
The contribution of the intestinal tract to differences in residual feed intake (RFI) has been inconclusively studied in chickens so far. It is also not clear if RFI-related differences in intestinal function are similar in chickens raised in different ...
Aschenbach, J., Ball, M. E. E., Ertl, R., Hawken, R. J., Hollmann, M., Lawlor, P. G. [u.v.m.], Magowan, E., Metzler-Zebeli, B. U., Molnár, A., Witter, K.   +9 more
core   +1 more source

Intestinal barrier: Molecular pathways and modifiers

World Journal of Gastrointestinal Pathophysiology, 2013
The gastrointestinal tract is frequently challenged by pathogens/antigens contained in food and water and the intestinal epithelium must be capable of rapid regeneration in the event of tissue damage. Disruption of the intestinal barrier leads to a number of immune-mediated diseases, including inflammatory bowel disease, food allergy, and celiac ...
Min Kyung, Jeon, Christina, Klaus, Elke, Kaemmerer, Nikolaus, Gassler   +3 more
openaire   +2 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

The barrier and the intestinal microflora - the factors determining the state of human health

Journal of Education, Health and Sport, 2019
Introduction and purpose: Protective function, immune and nutrition in the human body correspond to the intestinal barrier. As a result of excessive exposure to various factors often leads to damage or abnormalities in its functioning, which negatively ...
Sylwia Paulina Jopkiewicz
doaj   +3 more sources