Results 261 to 270 of about 352,113 (307)
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Current Opinion in Clinical Nutrition and Metabolic Care, 2002
Intestinal barrier function regulates transport and host defense mechanisms at the mucosal interface with the outside world. Transcellular and paracellular fluxes are tightly controlled by membrane pumps, ion channels and tight junctions, adapting permeability to physiological needs.
Daniel C, Baumgart, Axel U, Dignass
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Intestinal barrier function regulates transport and host defense mechanisms at the mucosal interface with the outside world. Transcellular and paracellular fluxes are tightly controlled by membrane pumps, ion channels and tight junctions, adapting permeability to physiological needs.
Daniel C, Baumgart, Axel U, Dignass
openaire +2 more sources
Apoptosis and Intestinal Barrier Function
Annals of the New York Academy of Sciences, 2000The signal transduction pathways of the induction of apoptosis in the gastrointestinal tract have in part been discovered. However, almost nothing is known about the functional influence of apoptotic signals on intestinal barrier function. In this study the effect of camptothecin-induced apoptosis in HT-29/B6 monolayers and the influence of apoptosis ...
C, Bojarski +7 more
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Glutamine and intestinal barrier function
Amino Acids, 2014The intestinal barrier integrity is essential for the absorption of nutrients and health in humans and animals. Dysfunction of the mucosal barrier is associated with increased gut permeability and development of multiple gastrointestinal diseases. Recent studies highlighted a critical role for glutamine, which had been traditionally considered as a ...
Bin, Wang +10 more
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Epithelial Barriers in Intestinal Inflammation
Antioxidants & Redox Signaling, 2011The gastrointestinal epithelium transports solutes and water between lumen and blood and at the same time forms a barrier between these compartments. This highly selective and regulated barrier permits ions, water, and nutrients to be absorbed, but normally restricts the passage of harmful molecules, bacteria, viruses and other pathogens.
Lena J, John +2 more
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Intestinal Barrier and Behavior
2016The intestinal barrier function contributes to gut homeostasis by modulating absorption of water, electrolytes, and nutrients from the lumen into the circulation while restricting the passage of noxious luminal substances and microorganisms. Chronic conditions such as rheumatoid arthritis, inflammatory bowel disease, and celiac disease are associated ...
M, Julio-Pieper, J A, Bravo
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NeoReviews, 2009
As the largest interface with the external environment, the mature intestinal epithelium has remarkable physiologic responsibilities. The intestine must function first as an organ of absorption and digestion while simultaneously protecting itself from the vast bacterial flora, array of food antigens, and physiochemical stresses caused by digestive and ...
Nancy A. Louis, Patricia W. Lin
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As the largest interface with the external environment, the mature intestinal epithelium has remarkable physiologic responsibilities. The intestine must function first as an organ of absorption and digestion while simultaneously protecting itself from the vast bacterial flora, array of food antigens, and physiochemical stresses caused by digestive and ...
Nancy A. Louis, Patricia W. Lin
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Intestinal Barrier Repair in Giardiasis
The Journal of Immunology, 2023Abstract Giardiasis is a common diarrheal disease caused by the protozoan parasite Giardia duodenalis. Acute symptoms can include diarrhea, but infections are often sub-clinical. It is transmitted via ingesting infectious cysts in contaminated food or water.
Rita Taye Kosile +3 more
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Intestinal Inflammation and Mucosal Barrier Function
Inflammatory Bowel Diseases, 2014Intestinal mucosal barrier function is the capacity of the intestine to provide adequate containment of luminal microorganisms and molecules while preserving the ability to absorb nutrients. The central element is the epithelial layer, which physically separates the lumen and the internal milieu and is in charge of vectorial transport of ions ...
Fermín, Sánchez de Medina +3 more
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Intestinal barriers protect against disease
Science, 2018Leaky cell-cell junctions contribute to inflammatory and autoimmune ...
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Nitric Oxide and Intestinal Barrier Failure
Seminars in Pediatric Surgery, 1999The systemic inflammatory response syndrome (SIRS) is a leading cause of morbidity and mortality in adults and children. Various proinflammatory mediators have been implicated in the pathogenesis of SIRS; however, their mechanisms of action are poorly defined.
E P, Nadler +3 more
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