Results 21 to 30 of about 352,113 (307)
Human organoids are superior to cell culture models for intestinal barrier research
Frontiers in Cell and Developmental Biology, 2023 Loss of intestinal epithelial barrier function is a hallmark in digestive tract inflammation. The detailed mechanisms remain unclear due to the lack of suitable cell-based models in barrier research.
Catherine Kollmann +10 more
doaj +1 more source
A Novel Non-invasive Method to Detect RELM Beta Transcript in Gut Barrier Related Changes During a Gastrointestinal Nematode Infection [PDF]
, 2019 Currently, methods for monitoring changes of gut barrier integrity and the associated immune response via non-invasive means are limited. Therefore, we aimed to develop a novel non-invasive technique to investigate immunological host responses ...
Affinass, Nicole +8 more
core +4 more sources
Enhancing intestinal barrier efficiency: A novel metabolic diseases therapy
Frontiers in Nutrition, 2023 Physiologically, the intestinal barrier plays a crucial role in homeostasis and nutrient absorption and prevents pathogenic entry, harmful metabolites, and endotoxin absorption.
Yaoyuan Zhang +9 more
doaj +1 more source
The food contaminant deoxynivalenol, decreases intestinal barrier permeability and reduces claudin expression [PDF]
, 2009 The gastrointestinal tract represents the first barrier against food contaminants as well as the first target for these toxicants. Deoxynivalenol (DON) is a mycotoxin that commonly contaminates cereals and causes various toxicological effects.
Bracarense, Ana-Paula +8 more
core +2 more sources
Stromal regulation of the intestinal barrier
Mucosal Immunology, 2023 The intestinal barrier is a complex structure that allows the absorption of nutrients while ensuring protection against intestinal pathogens and balanced immunity. The development and maintenance of a functional intestinal barrier is a multifactorial process that is only partially understood.
Sylvestre, Marvin +2 more
openaire +2 more sources
Cytokine tuning of intestinal epithelial function [PDF]
, 2018 The intestine serves as both our largest single barrier to the external environment and the host of more immune cells than any other location in our bodies.
Andrews, Caroline +2 more
core +7 more sources
Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli. [PDF]
, 2016 Pathobiont expansion, such as that of adherent-invasive Escherichia coli (AIEC), is an emerging factor associated with inflammatory bowel disease. The intestinal epithelial barrier is the first line of defense against these pathogens.
McCole, Declan F, Shawki, Ali
core +1 more source
Gastroenterology Research and Practice, 2022 Inflammatory bowel disease is a group of chronic, recurrent, nonspecific inflammatory diseases of the intestine that severely affect the quality of life of patients.
Yonggang Tian, Dekui Zhang
doaj +1 more source
The Journal of Poultry Science, 2023 Clostridium butyricum is an important probiotic for chickens and exerts various biological activities, including altering the composition of the intestinal microbiota, competing with other microorganisms for nutrients, improving the integrity of the ...
Min Liu +4 more
doaj +1 more source
Epithelial cell shedding and barrier function: a matter of life and death at the small intestinal villus tip [PDF]
, 2015 The intestinal epithelium is a critical component of the gut barrier. Composed of a single layer of intestinal epithelial cells (IECs) held together by tight junctions, this delicate structure prevents the transfer of harmful microorganisms, antigens ...
A. J. M. Watson +15 more
core +4 more sources