Intestinal barriers to water-soluble macromolecules [PDF]
Environmental Health Perspectives, 1979 Neonates of some species of mammals absorb water-soluble macromolecules from the lumen of the gut to the circulation. This is a means for providing the neonate with passive immunological protection. The accepted model for absorption of macromolecules, particularly immunoglobulin G (IgG), has at least three phases: adherence of the macromolecule to the ...
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Macrobiota — helminths as active participants and partners of the microbiota in host intestinal homeostasis [PDF]
, 2016 Important insights have recently been gained in our understanding of the intricate relationship in the intestinal milieu between the vertebrate host mucosal immune response, commensal bacteria, and helminths. Helminths are metazoan worms (macrobiota) and
Gause, William C., Maizels, Rick M.
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How do intestinal probiotics restore the intestinal barrier?
Frontiers in Microbiology, 2022 The intestinal barrier is a structure that prevents harmful substances, such as bacteria and endotoxins, from penetrating the intestinal wall and entering human tissues, organs, and microcirculation. It can separate colonizing microbes from systemic tissues and prevent the invasion of pathogenic bacteria.
Hong-Zhong Gou +14 more
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A fixed combination of probiotics and herbal extracts attenuates intestinal barrier dysfunction from inflammatory stress in an in vitro model using Caco-2 cells. [PDF]
, 2019 Background: Inflammatory Bowel Diseases (IBD), are considered a growing global disease, with about ten million people being affected worldwide. Maintenance of intestinal barrier integrity is crucial for preventing IBD onset and exacerbations. Some recent
Biagi, M +8 more
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Resveratrol in Intestinal Health and Disease: Focusing on Intestinal Barrier
Frontiers in Nutrition, 2022 The integrity of intestinal barrier determines intestinal homeostasis, which could be affected by various factors, like physical, chemical, and biological stimuli. Therefore, it is of considerable interest and importance to maintain intestinal barrier function.
Youxia Wang +10 more
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Intestinal Barrier Function in Gluten-Related Disorders [PDF]
, 2019 Gluten-related disorders include distinct disease entities, namely celiac disease, wheat-associated allergy and non-celiac gluten/wheat sensitivity. Despite having in common the contact of the gastrointestinal mucosa with components of wheat and other ...
Branchi, Federica +6 more
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Intestinal barrier in inflammatory bowel disease
World Journal of Gastroenterology, 2014 A complex mucosal barrier protects as the first line of defense the surface of the healthy intestinal tract from adhesion and invasion by luminal microorganisms. In this review, we provide an overview about the major components of this protective system as for example an intact epithelium, the synthesis of various antimicrobial peptides (AMPs) and the ...
Lena, Antoni +3 more
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The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors [PDF]
, 2015 OBJECTIVE: Gut barrier is a functional unit organized as a multi-layer system and its multiple functions are crucial for maintaining gut homeostasis. Numerous scientific evidences showed a significant association between gut barrier leaking and gastro ...
Bruno, G +5 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra +3 more
wiley +1 more source
Intestine‐Specific Expression of Human Chimeric Intestinal Alkaline Phosphatase Attenuates Western Diet‐Induced Barrier Dysfunction and Glucose Intolerance [PDF]
, 2018 Intestinal epithelial cell derived alkaline phosphatase (IAP) dephosphorylates/detoxifies bacterial endotoxin lipopolysaccharide (LPS) in the gut lumen.
Ghosh, Shobha +5 more
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