Results 91 to 100 of about 539,014 (352)

Hyperbaric Oxygen Treatment Improves Intestinal Barrier Function After Spinal Cord Injury in Rats

Frontiers in Neurology, 2020
Intestinal barrier dysfunction is often observed clinically after spinal cord injury (SCI) and seriously affects long-term quality of life. Hyperbaric oxygen (HBO) treatment has been proved to promote barrier function recovery after injury, but the ...
Xuehua Liu, Fang Liang, Jing Zhang, Zhuo Li, Jing Yang, Nan Kang   +5 more
doaj   +1 more source

Cigarette smoking alters intestinal barrier function and Peyer's Patch composition [PDF]

, 2011
Smokers have a two-fold increased risk to develop Crohn’s disease (CD). However, little is known about the mechanisms through which smoking affects CD pathogenesis. Interestingly, the Peyer’s patches in the terminal ileum are the sites where the first CD
Bracke, Ken, Brusselle, Guy, Cuvelier, Claude, Demoor, Tine, Lambrecht, Bart, Plantinga, Maud, VERSCHUERE, Stephanie   +6 more
core  

Campylobacter jejuni colonization promotes the translocation of Escherichia coli to extra-intestinal organs and disturbs the short-chain fatty acids profiles in the chicken gut [PDF]

, 2019
For a long time Campylobacter was only considered as a commensal microorganism in avian hosts restricted to the ceca, without any pathogenic features. The precise reasons for the symptomless chicken carriers are still unknown, but investigations of the ...
Aschenbach, J. R., Awad, W. A., Dublecz, F., Dublecz, K., Hess, C., Hess, M., Khayal, B.   +6 more
core   +1 more source

A Novel Postbiotic From Lactobacillus rhamnosus GG With a Beneficial Effect on Intestinal Barrier Function

Frontiers in Microbiology, 2019
It has long been known that probiotics can be used to maintain intestinal homeostasis and treat a number of gastrointestinal disorders, but the underlying mechanism has remained obscure.
Jie Gao, Yubin Li, Y. Wan, T. Hu, Liting Liu, Shaojie Yang, Z. Gong, Qing Zeng, Yi Wei, Weijun Yang, Zhijie Zeng, Xiaolong He, Sheng-He Huang, H. Cao   +13 more
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Anti-Hyperglycemic Agents in the Adjuvant Treatment of Sepsis: Improving Intestinal Barrier Function

Drug Design, Development and Therapy, 2022
Yi-Feng Wang, Jia-Wei Li, Da-Peng Wang, Ke Jin, Jiao-Jie Hui, Hong-Yang Xu Department of Critical Care Medicine, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi, Jiangsu, People’s Republic of ChinaCorrespondence: Jiao-Jie Hui ...
Wang YF, Li JW, Wang DP, Jin K, Hui JJ, Xu HY   +5 more
doaj  

Myosin light chain kinase mediates intestinal barrier disruption following burn injury. [PDF]

PLoS ONE, 2012
BACKGROUND: Severe burn injury results in the loss of intestinal barrier function, however, the underlying mechanism remains unclear. Myosin light chain (MLC) phosphorylation mediated by MLC kinase (MLCK) is critical to the pathophysiological regulation ...
Chuanli Chen, Pei Wang, Qin Su, Shiliang Wang, Fengjun Wang   +4 more
doaj   +1 more source

The Role of Intestinal Mucosal Barrier in Autoimmune Disease: A Potential Target

Frontiers in Immunology, 2022
Autoimmune diseases are a series of diseases involving multiple tissues and organs, characterized by the over production of abnormal multiple antibodies.
Jia An, Yuqing Liu, Yiqi Wang, Ru Fan, Xiaorong Hu, Fen Zhang, Jinhua Yang, Junwei Chen   +7 more
doaj   +1 more source

Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis [PDF]

, 2017
Background: Dysbiosis has been recently demonstrated in patients with ankylosing spondylitis (AS) but its implications in the modulation of intestinal immune responses have never been studied.
Alessandro, Riccardo, Ciccia, Francesco, Cypers, Heleen, Di Benedetto, Paola, Elewaut, Dirk, Fasano, Alessio, Gabrielli, Armando, Guggino, Giuliana, Luchetti, Michele Maria, Milling, Simon, Rizzo, Aroldo, Saieva, Laura, Stampone, Tommaso, Triolo, Giovanni   +13 more
core   +2 more sources