Results 171 to 180 of about 539,014 (352)

Monocyte-driven inflamm-aging reduces intestinal barrier function in females

Immunity & Ageing
Background The intestinal barrier encompasses physical and immunological components that act to compartmentalize luminal contents, such as bacteria and endotoxins, from the host.
Candice Quin, Jessica A. Breznik, Allison E. Kennedy, Erica N. DeJong, Catherine M. Andary, Sofya Ermolina, Donald J. Davidson, Jinhui Ma, Michael G. Surette, Dawn M. E. Bowdish   +9 more
doaj   +1 more source

Lactiplantibacillus plantarum ST-III and Lacticaseibacillus rhamnosus KF7 Enhance the Intestinal Epithelial Barrier in a Dual-Environment In Vitro Co-Culture Model

Microorganisms
Intestinal barrier hyperpermeability, which is characterised by impaired tight junction proteins, is associated with a variety of gastrointestinal and systemic diseases.
Yilin Zhang, Rachel C. Anderson, Chunping You, Ajitpal Purba, Minghui Yan, Paul Maclean, Zhenmin Liu, Dulantha Ulluwishewa   +7 more
doaj   +1 more source

Preferences for post‐traumatic osteoarthritis prevention strategies in individuals with anterior cruciate ligament injury

Arthritis Care &Research, Accepted Article.
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy, Lily Waddell, Adam Easterbrook, Jeffrey N. Katz, Cale Jacobs, Morgan Jones, Faith Selzer, Elena Losina, Liana Fraenkel, Nick Bansback   +9 more
wiley   +1 more source

Recent advances in measuring the effects of diet on gastrointestinal physiology: Probing the “leaky gut” and application of real‐time ultrasound

JGH Open
There is a large pool of ideas in both mainstream and non‐mainstream medicine on how diet can be manipulated in order to treat or prevent illnesses. Despite this, our understanding of how specific changes in diet influence the structure and function of ...
Tamara Mogilevski, Giovanni Maconi, Peter R Gibson   +2 more
doaj   +1 more source

Clinical Outcomes of Patients Within the Rheumatoid Arthritis Care Pathway Cohort at a Tertiary Care Integrated Delivery Network: A Comparison to Usual Care

Arthritis Care &Research, EarlyView.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multidisciplinary team‐based care.
Tarun Sharma, Tyson S. Barrett, Teigan Dwyer, Nancy Campbell, Jessica Heintzinger, Ellen Kraemer, Adam Dore, Susan Manzi   +7 more
wiley   +1 more source

Research Progress on the Relationship Between the Intestinal Barrier and Macrophages

Current Issues in Molecular Biology
The intestinal barrier serves as a crucial defense in the body, and a compromised integrity can lead to systemic health issues. Intestinal macrophages, as key components of the intestinal immune system, have a profound influence on intestinal homeostasis.
Shan Ma, Kecheng Zhu, Yan Liu, Jizhuang Wang   +3 more
doaj   +1 more source

The therapeutic management of gut barrier leaking: the emerging role for mucosal barrier protectors [PDF]

, 2015
OBJECTIVE: Gut barrier is a functional unit organized as a multi-layer system and its multiple functions are crucial for maintaining gut homeostasis. Numerous scientific evidences showed a significant association between gut barrier leaking and gastro ...
Bruno, G, Franceschi, F, Gasbarrini, A, Lopetuso, Lr, Petito, V, Scaldaferri, F   +5 more
core  

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall, Cinthia Blat, Eric Roberts, Jean W. Liew, Katherine Wysham, Namrata Singh, Janna Friedly, Lianne S. Gensler, Gabriela Schmajuk, Jinoos Yazdany   +9 more
wiley   +1 more source

Malvidin-3-O-galactoside ameliorates small intestinal mucosal barrier function via Notch pathway

Food Science and Human Wellness
The intestinal mucosa is the intestinal lumen tissue that protects the intestine from invasion, maintains intestinal barrier function, and participates in the immune response.
Yuehua Wang, Ying Zhang, Bo Zhang, Jiaying Zhang, Hui Tan, Li Li, Xinyao Jiao   +6 more
doaj   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, In collaboration with the Consensus Expert Panel (CEP) members   +19 more
wiley   +1 more source