Results 301 to 310 of about 539,014 (352)

Intestinal mucosal barrier function in health and disease

Nature Reviews Immunology, 2009
Mucosal surfaces are lined by epithelial cells. These cells establish a barrier between sometimes hostile external environments and the internal milieu. However, mucosae are also responsible for nutrient absorption and waste secretion, which require a selectively permeable barrier.
Jerrold R Turner
exaly   +4 more sources

Dendrobium fimbriatum Hook polysaccharide ameliorates dextran-sodium-sulfate-induced colitis in mice via improving intestinal barrier function, modulating intestinal microbiota, and reducing oxidative stress and inflammatory responses.

Food & Function, 2021
The ameliorative effect of Dendrobium fimbriatum polysaccharide (cDFPW1) on ulcerative colitis (UC) was investigated using a dextran-sodium-sulfate-induced (DSS-induced) mouse model in the present study.
Yu-Jing Wang, Qiang‐Ming Li, X. Zha, Jian-ping Luo   +3 more
semanticscholar   +1 more source

Intestinal barrier function

Current Opinion in Clinical Nutrition and Metabolic Care, 2002
Intestinal barrier function regulates transport and host defense mechanisms at the mucosal interface with the outside world. Transcellular and paracellular fluxes are tightly controlled by membrane pumps, ion channels and tight junctions, adapting permeability to physiological needs.
Daniel C, Baumgart, Axel U, Dignass
openaire   +2 more sources

Apoptosis and Intestinal Barrier Function

Annals of the New York Academy of Sciences, 2000
The signal transduction pathways of the induction of apoptosis in the gastrointestinal tract have in part been discovered. However, almost nothing is known about the functional influence of apoptotic signals on intestinal barrier function. In this study the effect of camptothecin-induced apoptosis in HT-29/B6 monolayers and the influence of apoptosis ...
C, Bojarski, K, Bendfeldt, A H, Gitter, J, Mankertz, M, Fromm, S, Wagner, E O, Riecken, J D, Schulzke   +7 more
openaire   +2 more sources

Glutamine and intestinal barrier function

Amino Acids, 2014
The intestinal barrier integrity is essential for the absorption of nutrients and health in humans and animals. Dysfunction of the mucosal barrier is associated with increased gut permeability and development of multiple gastrointestinal diseases. Recent studies highlighted a critical role for glutamine, which had been traditionally considered as a ...
Bin, Wang, Guoyao, Wu, Zhigang, Zhou, Zhaolai, Dai, Yuli, Sun, Yun, Ji, Wei, Li, Weiwei, Wang, Chuang, Liu, Feng, Han, Zhenlong, Wu   +10 more
openaire   +2 more sources

Intestinal Inflammation and Mucosal Barrier Function

Inflammatory Bowel Diseases, 2014
Intestinal mucosal barrier function is the capacity of the intestine to provide adequate containment of luminal microorganisms and molecules while preserving the ability to absorb nutrients. The central element is the epithelial layer, which physically separates the lumen and the internal milieu and is in charge of vectorial transport of ions ...
Fermín, Sánchez de Medina, Isabel, Romero-Calvo, Cristina, Mascaraque, Olga, Martínez-Augustin   +3 more
openaire   +2 more sources

An arabinogalactan from Lycium barbarum attenuates DSS-induced chronic colitis in C57BL/6J mice associated with the modulation of intestinal barrier function and gut microbiota.

Food & Function, 2021
Ulcerative colitis (UC) is an incurable chronic inflammation of the enteric tract. The aim of this study was to investigate the protective effects of arabinogalactan from Lycium barbarum on DSS-induced chronic colitis.
Cui Cao, B. Zhu, Zhengqi Liu, Xue Wang, Chunqing Ai, Guiping Gong, Minghua Hu, Linjuan Huang, Shuang Song   +8 more
semanticscholar   +1 more source

Intestinal epithelial barrier functions in ageing

Ageing Research Reviews, 2019
The intestinal epithelial barrier protects the mucosa of the gastrointestinal (GI)-tract and plays a key role in maintaining the host homeostasis. It encompasses several elements that include the intestinal epithelium and biochemical and immunological products, such as the mucus layer, antimicrobial peptides (AMPs) and secretory immunologlobulin A ...
Jacopo J V, Branca, Massimo, Gulisano, Claudio, Nicoletti   +2 more
openaire   +2 more sources

Probiotic bacteria and intestinal epithelial barrier function

American Journal of Physiology-Gastrointestinal and Liver Physiology, 2010
The intestinal tract is a diverse microenvironment where more than 500 species of bacteria thrive. A single layer of epithelium is all that separates these commensal microorganisms and pathogens from the underlying immune cells, and thus epithelial barrier function is a key component in the arsenal of defense mechanisms required to prevent infection ...
Christina L, Ohland, Wallace K, Macnaughton   +1 more
openaire   +2 more sources

Resveratrol regulates intestinal barrier function in cyclophosphamide-induced immunosuppressive mice.

The Journal of the Science of Food and Agriculture, 2021
BACKGROUND Resveratrol, a kind of polyphenolic phytoalexin, could be obtained from numerous natural foods. Although resveratrol is demonstrated to have various bioactivities, little is known about the regulation of intestinal barrier function under ...
Xu Song, Lin Liu, S. Peng, Tao Liu, Yaqin Chen, R. Jia, Y. Zou, Lixia Li, Xinghong Zhao, Xiaoxia Liang, Huaqiao Tang, Z. Yin   +11 more
semanticscholar   +1 more source