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Intestinal Epithelial Cells Control Dendritic Cell Function

Annals of the New York Academy of Sciences, 2004
Abstract: Dendritic cells (DCs) comprise a family of cells specializing in antigen capture and presentation to T cells. We have recently shown that DC play an active role in bacterial uptake across mucosal surfaces. Indeed, DC are able to open tight junctions and to sample antigens directly across epithelia, both in vitro and in vivo.
Rimoldi M.   +4 more
openaire   +4 more sources

Intestinal selenoprotein P in epithelial cells and in plasma cells

Archives of Biochemistry and Biophysics, 2014
The micronutrient selenium and selenium-containing selenoproteins are involved in prevention of inflammation and carcinogenesis in the gut. Selenoprotein P (Sepp1), the plasma selenium transport protein, is secreted primarily from hepatocytes, but Sepp1 mRNA is also abundant in the intestine. By immunofluorescence analysis, we show that Sepp1 levels in
Bodo, Speckmann   +4 more
openaire   +2 more sources

Primary Cell Culture of Turkey Intestinal Epithelial Cells

Avian Diseases, 1996
Primary cell culture has been widely used in various types of studies and proven useful for the isolation and identification of avian pathogens. Difficulties in growing intestinal epithelial cells in vitro have limited their use for such studies. In the present study, a co-culture system was developed for the primary culture of intestinal epithelial ...
A, Ali, D L, Reynolds
openaire   +2 more sources

Osmosignaling and Volume Regulation in Intestinal Epithelial Cells

2007
Most cells have to perform their physiological functions under a variable osmotic stress, which, because of the relatively high permeability of the plasma membrane for water, may result in frequent alterations in cell size. Intestinal epithelial cells are especially prone to changes in cell volume because of their high capacity of salt and water ...
Lim, Christina   +3 more
openaire   +2 more sources

Cell death of intestinal epithelial cells in intestinal diseases.

Sheng li xue bao : [Acta physiologica Sinica], 2020
Gut injury continues to be the devastating and unpredictable critical illness associated with increased cell death of intestinal epithelial cells (IECs). The IECs, immune system and microbiome are the interrelated entities to maintain normal intestinal homeostasis and barrier integrity.
Saravanan, Subramanian   +2 more
openaire   +1 more source

Intestinal Epithelial Cell Regulation of Mucosal Inflammation

Immunologic Research, 2004
The intestinal epithelium serves as one of human's primary interfaces with the outside world. This interface is very heavily colonized with bacteria and yet permits absorption of life-sustaining nutrients while protecting the tissues below from microbial onslaught.
Yimin, Yu   +2 more
openaire   +2 more sources

The fate of epithelial cells in the human large intestine

Pathology, 1999
One hundred and forty biopsies of the colon and rectum, collected during routine colonoscopies of 51 patients aged 19 to 74 years, were examined using light microscopy and transmission and scanning electron microscopy. The results indicated that surface epithelial cells undergo apoptosis, passing through fenestrations in the basement membrane to where ...
D H, Barkla, P R, Gibson
openaire   +2 more sources

Epithelial Cell Contributions to Intestinal Immunity

2015
The epithelial surfaces of the mammalian intestine interface directly with the external environment and thus continuously encounter pathogenic bacteria, fungi, viruses, and parasites. The intestinal epithelium is also closely associated with complex communities of symbiotic microorganisms.
openaire   +2 more sources

Cultured Intestinal Epithelial Cell Models

1996
In vitro systems such as brush border membrane vesicles (BBMV), basolateral membrane vesicles (BLMV), perfused intestinal loops, stripped intestinal mucosa, and isolated enterocytes have been used to study mucosal drug absorption. Isolated enterocytes should permit the determination of transmembrane transport in the presence of cellular metabolism ...
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Interactions between Epithelial Cells and Immune Cells in the Intestine

Annals of the New York Academy of Sciences, 1998
ABSTRACT: Not merely a passive barrier as previously assumed, epithelial cells act as sensitive indicators of infection that initiate defense responses. Noninvasive as well as invasive organisms have been demonstrated to elicit production of chemoattractants.
openaire   +2 more sources

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