Results 251 to 260 of about 5,424,793 (311)

Mitochondria‐Targeted Multimodal Nanotherapeutics Suppress Oxidized mtDNA‐Driven Inflammation at the Source

open access: yesAdvanced Science, EarlyView.
Ox‐mtDNA fragments escaping from mitochondria drive robust inflammatory responses. A targeted nanoplatform simultaneously inhibits mitochondrial FEN1‐mediated mtDNA cleavage and scavenges ROS, preventing the generation of immunogenic Ox‐mtDNA fragments. The released SeNPs further promote autophagic clearance of cytosolic mtDNA. Consequently, cGAS‐STING,
Wen‐Ling Li   +7 more
wiley   +1 more source

Urolithin A activates aryl hydrocarbon receptor-NLRP6-mediated pathways in intestinal epithelial cells to modulate mucosal immunity and strengthen gut barrier integrity. [PDF]

open access: yesNat Commun
Ghosh S   +13 more
europepmc   +1 more source

Live and heat-treated <i>Lactiplantibacillus plantarum</i> induce distinct metabolic and immune responses in intestinal epithelial cells. [PDF]

open access: yesiScience
Matsumoto K   +17 more
europepmc   +1 more source
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The intestinal epithelial stem cell

BioEssays, 2002
AbstractThis article considers the role of the adult epithelial stem cell, with particular reference to the intestinal epithelial stem cell. Although the potential of adult stem cells has been revealed in a number of recent publications, the organization and control of the stem cell hierarchy in epithelial tissues is still not fully understood.
Emma, Marshman   +2 more
openaire   +2 more sources

Intestinal Epithelial‐Mesenchymal Cell Interactions

Annals of the New York Academy of Sciences, 1998
ABSTRACT: Intestinal morphogenesis, as well as maintenance of the stem cell population and of the steady state between cell proliferation and differentiation, results from controlled cell interactions. There is growing evidence that the mesenchymal cells control epithelial cell behavior via their own expression and induction in the epithelial cells of
Kedinger, Michèle   +5 more
openaire   +2 more sources

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