Results 51 to 60 of about 263,980 (286)
Frontiers in Immunology, 2023 IntroductionWe have previously demonstrated that a pathologic downregulation of peroxisome proliferator-activated receptor–gamma coactivator 1-alpha (PGC1α) within the intestinal epithelium contributes to the pathogenesis of inflammatory bowel disease ...
Elizabeth A. Novak +20 more
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Infection-generated electric field in gut epithelium drives bidirectional migration of macrophages. [PDF]
, 2019 Many bacterial pathogens hijack macrophages to egress from the port of entry to the lymphatic drainage and/or bloodstream, causing dissemination of life-threatening infections. However, the underlying mechanisms are not well understood.
Ferreira, Fernando +14 more
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STUDIES ON SMALL INTESTINAL CRYPT EPITHELIUM [PDF]
The Journal of Cell Biology, 1963 Small intestinal crypt epithelium obtained from normal fasting humans by peroral biopsy of the mucosa was studied with the electron microscope. Paneth cells were identified at the base of the crypts by their elaborate highly organized endoplasmic reticulum, large secretory granules, and small lysosome-like dense bodies within the cytoplasm ...
openaire +1 more source
Intrinsic Defense Mechanisms of the Intestinal Epithelium [PDF]
Cell Host & Microbe, 2016 The intestinal epithelium is a single cell layer that facilitates the absorption of nutrients but also provides a tight barrier to prevent pathogen invasion and dissemination of commensal microbes. Specialized epithelial cells of the gastrointestinal tract achieve this frontline defense by working in concert with lymphoid, myeloid, and stromal cells to
Deepshika, Ramanan, Ken, Cadwell
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Murine intestinal organoids resemble intestinal epithelium in their microRNA profiles [PDF]
Bioscience, Biotechnology, and Biochemistry, 2018 Abstract Intestinal organoids were established as an ex vivo model of the intestinal epithelium. We investigated whether organoids resemble the intestinal epithelium in their microRNA (miRNA) profiles. Total RNA samples were obtained from crypt and villus fractions in murine intestine and from cultured organoids.
Ohsaka, Fumina, Sonoyama, Kei
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Cross-Talk Between the Intestinal Epithelium and Salmonella Typhimurium
Frontiers in Microbiology, 2022 Salmonella enterica serovars are invasive gram-negative bacteria, causing a wide range of diseases from gastroenteritis to typhoid fever, representing a public health threat around the world.
Sandrine Ménard +7 more
doaj +1 more source
Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]
, 1998 Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Bosbach, R. +3 more
core +1 more source
Metabolic fuel selection by intestinal epithelium [PDF]
Proceedings of the Nutrition Society, 1995 RESUME Les nutriments prCsents dans la lumikre intestinale aprks un repas sont absorb& sklectivement par 1’CpithClium intestinal. L’absorption varie avec le mode d’alimentation et avec les conditions physiologiques (croissance, lactation, vieillissement) et avec les conditions pathologiques liCes ou non a la nutrition.
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PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection. [PDF]
, 2019 Chronic gut inflammatory diseases are associated with disruption of intestinal epithelial barriers and impaired mucosal immunity. HIV-1 (HIV) causes depletion of mucosal CD4+ T cells early in infection and disruption of gut epithelium, resulting in ...
Arredondo, Juan +13 more
core
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source