Results 51 to 60 of about 3,701,616 (329)

Intestinal transplantation under tacrolimus monotherapy after perioperative lymphoid depletion with rabbit anti-thymocyte globulin (thymoglobulin®) [PDF]

, 2005
Modifications in the timing and dosage of immunosuppression can ameliorate the morbidity and mortality that has prevented widespread use of intestinal transplantation (ITx) in children.
Abu-Elmagd, K, Bond, GJ, Macedo, C, Mazariegos, GV, Murase, N, Peters, J, Reyes, J, Sindhi, R, Starzl, TE   +8 more
core   +1 more source

An Observational Study of Smoflipid vs Intralipid on the Evolution of Intestinal Failure-Associated Liver Disease in Infants With Intestinal Failure.

JPEN - Journal of Parenteral and Enteral Nutrition, 2019
BACKGROUND SMOFlipid has a more diverse lipid profile than traditional Intralipid and has become the standard lipid for patients in our intestinal rehabilitation program.
C. Belza, John C. Wales, G. Courtney-Martin, N. De Silva, Y. Avitzur, P. Wales   +5 more
semanticscholar   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Intestinal Failure and Aberrant Lipid Metabolism in Patients With DGAT1 Deficiency

Gastroenterology, 2018
Background & Aims Congenital diarrheal disorders are rare inherited intestinal disorders characterized by intractable, sometimes life-threatening, diarrhea and nutrient malabsorption; some have been associated with mutations in diacylglycerol ...
Jorik M. van Rijn, R. Ardy, Z. Kuloğlu, Bettina Härter, Désirée Y. van Haaften-Visser, H. P. van der Doef, Marliek van Hoesel, A. Kansu, A. V. van Vugt, M. Thian, F. Kokke, A. Krolo, M. K. Başaran, N. Kaya, A. Ü. Aksu, B. Dalgıç, F. Ozçay, Z. Barış, R. Kain, E. Stigter, K. Lichtenbelt, Maarten Massink, K. Duran, J. Verheij, D. Lugtenberg, P. Nikkels, H. G. Brouwer, H. Verkade, R. Scheenstra, B. Spee, E. Nieuwenhuis, P. Coffer, A. Janecke, G. van Haaften, R. Houwen, T. Müller, S. Middendorp, K. Boztug   +37 more
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Clinical intestinal transplantation: New perspectives and immunologic considerations [PDF]

, 1998
Background: Although tacrolimus-based immunosuppression has made intestinal transplantation feasible, the risk of the requisite chronic high- dose treatment has inhibited the widespread use of these procedures.
Abu-Elmagd, K, Bueno, J, Demetris, J, Fawzy, AT, Fung, JJ, Furukawa, H, Irish, W, Lee, R, McMichael, J, Murase, N, Rakela, J, Rao, A, Reyes, J, Starzl, TE, Todo, S   +14 more
core   +1 more source

Monitoring of long‐term parenteral nutrition in children with intestinal failure

JGH Open, 2019
Pediatric intestinal failure (IF) is a rare and complex condition associated with significant morbidity and mortality. It is defined as the reduction of gut mass or function below the minimal needed for absorption of nutrients and fluid to sustain life ...
Boutaina Zemrani, J. Bines
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Alcohol Withdrawal – Therapeutical Management in Surgical Patients with Upper Intestinal Bleeding [PDF]

, 2015
Psychological dependence involves a desire to use a drug to avoid the unpleasant withdrawal syndrome that results from cessation of exposure to it. Alcohol withdrawal syndrome is one of the most feared complications of alcohol addiction and sometimes can
Bogdan, Popescu, Cristian, Bălălău, Denisa, Cobani Oana, Gloria, Trambitasu, Negrei, Carolina, Valentin, Scăunașu Răzvan   +5 more
core   +4 more sources

Outcomes of Children with Chronic Intestinal Failure: Experience Over Two Decades at a Tertiary Paediatric Hospital.

Journal of Pediatric Gastroenterology and Nutrition - JPGN, 2019
BACKGROUND & AIMS To aid decisions on prognosis and transplantation, this study describes the outcome of children with intestinal failure managed by the multidisciplinary intestinal rehabilitation program at the Royal Children's Hospital, Melbourne ...
S. C. Jo, Z. McCallum, Helen Shalley, M. Peterkin, Elizabeth Rogers, G. Paxton, T. Wong, J. Bines   +7 more
semanticscholar   +1 more source