Results 51 to 60 of about 225,155 (251)

Gastric bypass reversal in patients with short bowel syndrome

Intestinal Failure
Background: 5–10 % patients developing short bowel syndrome (SBS) have undergone a previous gastric bypass (GBP) for morbid obesity. The benefits of restoring gastric anatomy in these patients is assumed but remains unclear.
Jon S. Thompson, Fedja A. Rochling, Elizabeth Lyden, Shaheed Merani, Luciano Vargas, Wendy J. Grant, Alan N. Langnas, David F. Mercer   +7 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Characteristics and clinical outcomes of pediatric patients following massive bowel resection: A retrospective cohort study

Intestinal Failure
Background: Massive bowel resection (MBR), defined as residual small bowel
Clarelle L. Gonsalves, Christina Belza, Glenda Courtney-Martin, Yaron Avitzur, Jill Quirt, Victoria Srbely, Paul W. Wales   +6 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Perspectives of intestinal rehabilitation providers on the use of oral rehydration solutions for pediatric patients with short bowel syndrome

Intestinal Failure
Background: Patients with short bowel syndrome (SBS) have a loss of absorptive bowel surface area and are at risk for dehydration. Oral rehydration solutions (ORS) promote intestinal fluid absorption and may be used to maintain adequate hydration ...
Juliana Kennedy, Grace Altamura-Murgia, Maryanna Tosi, Kishore Iyer, Joanne Lai   +4 more
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

A neonatal intensive care nurse experience of an automated chyme reinfusion therapy device: A case report describing use in a neonate with necrotising enterocolitis

Intestinal Failure
Background: Neonatal intestinal failure related to double enterostomies is rare and associated with high morbidity and mortality. Chyme reinfusion therapy (CRT) remediates high outputs and improves nutrition and electrolyte balance of neonates.
Taylor Harrington, Emma Ludlow
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Combination of anti-TNFα therapy and surgical resection for severe chronic intestinal rejection: A case report

Intestinal Failure
Background: Acute cellular rejection (ACR) is a well-recognised cause of graft failure in intestinal transplant (ITx) recipients. Management of ACR is with intravenous (IV) steroids, increased immunosuppression and T-cell depleting therapies.
Katrina Tan, Elizabeth Low, Graham Starkey, Khashayar Asadi, Adam Testro, Darren Wong   +5 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source