Results 81 to 90 of about 3,701,616 (329)

Long-term Outcome After Nonvascularized Rectus Fascia Transplantation in Solid Organ Transplantation: A Global Multicenter IIRTA Survey

Transplantation Direct
Background. Abdominal wall (AW) closure after solid organ transplantation (SOT) is challenging in case of loss of abdominal domain and/or large-for-size grafts. Primary closure is crucial to avoid open abdomen-associated morbidity and mortality.
Nele Van De Winkel, MD, Ewout Muylle, BSc, Emilio Canovai, MD, PhD, Irum Amin, MD, Andrew Butler, MD, PhD, Rodrigo Vianna, MD, Gennaro Selvaggi, MD, Pablo Farinelli, MD, Gabriel Gondolesi, MD, Carmelo Loinaz, MD, PhD, Iago Justo, MD, PhD, Hector Vilca-Melendez, MD, Ulrika Skogsberg Dahlgren, MD, Gustaf Herlenius, MD, PhD, Alireza Shamsaeefar, MD, Hamed Nikoupour, MD, Antoine Dubois, MD, Marc Miserez, MD, PhD, André D’Hoore, MD, PhD, Robert Venick, MD, Jacques Pirenne, MD, PhD, Laurens J. Ceulemans, MD, PhD   +21 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Colonic dilation is associated with increased central line associated blood stream infection for patients with intestinal failure

Intestinal Failure
Introduction: Management of intestinal failure involves supplemental nutrition and complication minimization to achieve enteral autonomy. Previous research to identify prognostic factors in IF focused on the small bowel, yet little work has been done to ...
Pamela Emengo, Shweta S. Namjoshi, James C.Y. Dunn   +2 more
doaj   +1 more source

Home parenteral nutrition with an omega-3-fatty-acid-enriched MCT/LCT lipid emulsion in patients with chronic intestinal failure (the HOME study):study protocol for a randomized, controlled, multicenter, international clinical trial [PDF]

, 2019
BACKGROUND: Home parenteral nutrition (HPN) is a life-preserving therapy for patients with chronic intestinal failure (CIF) indicated for patients who cannot achieve their nutritional requirements by enteral intake.
A Van Gossum, A.M. Eltweri, Alastair Forbes, AR Heller, Bernhard Glotzbach, CJ Jones, Cécile Chambrier, DL Burns, E Venecourt-Jackson, EM Tillman, Farooq Rahman, Geert Wanten, GJ Wanten, H Baldermann, Ivan R. Diamond, J Wang, Jacek Sobocki, K Mayer, Kinga Szczepanek, KM Gura, L Pironi, L Pironi, Loris Pironi, M Cavicchi, M Rubin, M Staun, Marek Kunecki, MS Mundi, MS Mundi, MW Wichmann, Nicole Lincke, O Goulet, PB Jeppesen, PT Clayton, RT Hurt, S Klek, S Klek, Sheldon C. Cooper, Simon Gabe, Stanislaw Klek, T Grau-Carmona, W Lehmacher, Z Xu   +42 more
core   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

The negative impact on sleep for caregivers of children with intestinal failure on long-term parenteral nutrition

Intestinal Failure
Objectives: Survival rates for children with intestinal failure (IF) have improved with care provided in the home by family caregivers. Our objective was to compare total nocturnal sleep time (TST-N) in caregivers of children with IF on home PN to ...
Christina Belza, Paul W. Wales, Darcy Fehlings, Wendy J. Ungar, Yaron Avitzur, Robyn Stremler   +5 more
doaj   +1 more source

The feasibility of wireless capsule endoscopy in detecting small intestinal pathology in children under the age of 8 years: a multicentre European study. [PDF]

, 2009
Objective: To systematically evaluate the feasibility and methodology to carry out wireless capsule endoscopy (WCE) in children
Bufler, Philip, Fritscher-Ravens, A., Milla, P., Nuutinen, H., Ruuska, T., Scherbakov, P., Tabbers, M., Thomson, M., Torroni, F.   +8 more
core   +3 more sources

Parenteral Nutrition and Intestinal Failure

Nutrients, 2017
Severe short bowel syndrome (SBS) is a major cause of chronic (Type 3) intestinal failure (IF) where structural and functional changes contribute to malabsorption and risk of micronutrient deficiencies.
B. Bielawska, J. Allard
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Evolution of intestinal and multivisceral transplantation: A thirty-year United States perspective

Intestinal Failure
Background: The field of intestinal transplantation has significantly changed since the report of the first successful transplant in 1988. This report seeks to describe the trends in intestinal transplantation utilization and outcomes over time in the ...
Mariya L. Samoylova, Samuel J. Kesseli, Christine Park, John Yerxa, Simon Horslen, Syed-Mohammed Jafri, Alisha Mavis, Thomas Schiano, Bryant Summers, Andrew S. Barbas, Brian I. Shaw, Debra L. Sudan, M. Cristina Segovia   +12 more
doaj   +1 more source