Results 41 to 50 of about 556,223 (266)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Intestinal microbiota and health

Türkiye Halk Sağlığı Dergisi, 2018
Each organ has a unique microbiota, formerly known as its flora. In discussions around microbiota, intestinal microbiota comes to mind first. Microbes in the intestinal microbiota are essential for shaping and maintaining human physiology, and play an active role in hemostasis.
Kamer Kalip, Nazlı Atak
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Linking Human Milk Oligosaccharides, Infant Fecal Community Types, and Later Risk To Require Antibiotics

mBio, 2020
Human milk oligosaccharides (HMOs) may provide health benefits to infants partly by shaping the development of the early-life intestinal microbiota. In a randomized double-blinded controlled multicentric clinical trial, healthy term infants received ...
Bernard Berger, Nadine Porta, Francis Foata, Dominik Grathwohl, Michèle Delley, Deborah Moine, Aline Charpagne, Léa Siegwald, Patrick Descombes, Philippe Alliet, Giuseppe Puccio, Philippe Steenhout, Annick Mercenier, Norbert Sprenger   +13 more
doaj   +1 more source

Dietary energy and protein levels on lactation performance and progeny growth of Hu sheep

Journal of Applied Animal Research, 2022
This experiment aimed to investigate the effects of dietary energy or protein levels on lactation performance and progeny growth of Hu sheep. Thirty early lactation ewes with twin litters were assigned into five treatments (E1, E2 = P2, E3, P1, P3; n = 6)
Shi-feng Luo, Yan-can Wang, Xin Wang, Chun-peng Dai, Qi-ye Wang   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Zebrafish cobll1a regulates lipid homeostasis via the RA signaling pathway

Frontiers in Cell and Developmental Biology
Background:The COBLL1 gene has been implicated in human central obesity, fasting insulin levels, type 2 diabetes, and blood lipid profiles. However, its molecular mechanisms remain largely unexplored.Methods:In this study, we established cobll1a mutant ...
Ting Zeng, Ting Zeng, Jinrui Lv, Jinrui Lv, Jiaxin Liang, Jiaxin Liang, Binling Xie, Binling Xie, Ling Liu, Ling Liu, Yuanyuan Tan, Yuanyuan Tan, Junwei Zhu, Junwei Zhu, Jifan Jiang, Jifan Jiang, Huaping Xie, Huaping Xie   +17 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

RNA Interference Targeting Testis-Specific Serine/Threonine Protein Kinase 1 (TSSK1) Gene Triggers Male Infertility in Zeugodacus tau

Insects
Zeugodacus tau, a highly destructive agricultural quarantine pest causing severe economic losses to global fruit crops, urgently requires the development of male fertility-based control strategies.
Xinyao Huang, Wen Wen, Sihong Chen, Qiong Zhou, Wei Peng   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source