Results 61 to 70 of about 998,280 (242)

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Oral supplementation of Pediococcus pentosaceus SMM847 ameliorates hyperuricemia in rats and alcohol-induced injury in mice

Applied and Environmental Microbiology
Excessive dietary purine intake can lead to hyperuricemia, facilitating the precipitation and deposition of monosodium urate crystals in joints, which subsequently triggers inflammatory cascades leading to gout.
Yuxin Cao, Linfeng Wang, Cailing Ren, Chenxi Li, Yang Liu, Tong Zhang, Mengjiao Luo, Pan Zhao, Ruijuan Li, Jun Fu, Jia Yin   +10 more
doaj   +1 more source

Linking Human Milk Oligosaccharides, Infant Fecal Community Types, and Later Risk To Require Antibiotics

mBio, 2020
Human milk oligosaccharides (HMOs) may provide health benefits to infants partly by shaping the development of the early-life intestinal microbiota. In a randomized double-blinded controlled multicentric clinical trial, healthy term infants received ...
Bernard Berger, Nadine Porta, Francis Foata, Dominik Grathwohl, Michèle Delley, Deborah Moine, Aline Charpagne, Léa Siegwald, Patrick Descombes, Philippe Alliet, Giuseppe Puccio, Philippe Steenhout, Annick Mercenier, Norbert Sprenger   +13 more
doaj   +1 more source

Effect of Lactobacillus rhamnosus HN001 and Bifidobacterium longum BB536 on the healthy gut microbiota composition at phyla and species level: a preliminary study [PDF]

, 2017
AIM: To evaluate the ability of Lactobacillus rhamnosus HN001 and Bifidobacterium longum BB536 to colonize the intestinal environment of healthy subjects and modify the gut microbiota composition.
De Grandi, Roberta, De Vecchi, Elena, Drago, Lorenzo, Stronati, Laura, Toscano, Marco   +4 more
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Dietary energy and protein levels on lactation performance and progeny growth of Hu sheep

Journal of Applied Animal Research, 2022
This experiment aimed to investigate the effects of dietary energy or protein levels on lactation performance and progeny growth of Hu sheep. Thirty early lactation ewes with twin litters were assigned into five treatments (E1, E2 = P2, E3, P1, P3; n = 6)
Shi-feng Luo, Yan-can Wang, Xin Wang, Chun-peng Dai, Qi-ye Wang   +4 more
doaj   +1 more source

Age and Sex Distribution of Intestinal Parasitic Infection Among HIV Infected Subjects in Abeokuta, Nigeria [PDF]

, 2004
Intestinal parasitic infection has been a major source of disease in tropical countries especially among HIV patients. The distribution of intestinal parasite among two hundred and fifteen (215) subjects with mean age of 32 years, comprising of 35 HIV ...
Adeyeba Adegboyega, Dr. Oluwaseyi, Okodua, Dr. Marcellinus, Okpala Obi, Dr. Herbert, Tatfeng Mirabeau, Dr. Youtchou   +3 more
core  

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego, Kellee Parker, William C. Thomsen, James B. Ford, Mallorie B. Heneghan, David Spencer Mangum, Jennifer L. McNeer, Luke D. Maese, Claire E. F. Miller, Richard Lemons, Taumoha Ghosh   +10 more
wiley   +1 more source

Zebrafish cobll1a regulates lipid homeostasis via the RA signaling pathway

Frontiers in Cell and Developmental Biology
Background:The COBLL1 gene has been implicated in human central obesity, fasting insulin levels, type 2 diabetes, and blood lipid profiles. However, its molecular mechanisms remain largely unexplored.Methods:In this study, we established cobll1a mutant ...
Ting Zeng, Ting Zeng, Jinrui Lv, Jinrui Lv, Jiaxin Liang, Jiaxin Liang, Binling Xie, Binling Xie, Ling Liu, Ling Liu, Yuanyuan Tan, Yuanyuan Tan, Junwei Zhu, Junwei Zhu, Jifan Jiang, Jifan Jiang, Huaping Xie, Huaping Xie   +17 more
doaj   +1 more source