Results 51 to 60 of about 190,131 (263)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
GASTROINTESTINAL TRACT, MICROFLORA AND IMMUNITY
Педиатрическая фармакология, 2009 The article highlights the issues of microflora and immunity of gastrointestinal tract. It provides data on principle functions of normal flora, influence of different factors on colonizational resistance development of an organism.
T.S. Lazareva, F.F. Zhvaniya
doaj +2 more sources
Variation and immunity to intestinal worms
Parasitology, 2002 Genetically determined variation in host capacity to express resistance to a given parasite plays a major role in determining the outcome of infection. It can be assumed that the same is true of variation in parasites, but very much less is known of its influence on the host–parasite relationship.
D, Wakelin, S E, Farias, J E, Bradley
openaire +2 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Probiotics Regulate Gut Microbiota: An Effective Method to Improve Immunity
Molecules, 2021 Probiotics are beneficial active microorganisms that colonize the human intestines and change the composition of the flora in particular parts of the host. Recently, the use of probiotics to regulate intestinal flora to improve host immunity has received
Xinzhou Wang, Peng Zhang, Xin Zhang
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 SARS-CoV-2 causes a spectrum of clinical symptoms from respiratory damage to gastrointestinal disorders. Intestinal infection of SARS-CoV-2 triggers immune response.
Lijuan Zhang +7 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Advanced ScienceThis study investigates how microbiome colonization influences the development of intestinal type 3 immunity in neonates. The results showed that reduced oxygen levels in the small intestine of neonatal rats induced by Saccharomyces boulardii accelerated
Zhipeng Yang +7 more
doaj +1 more source
Research progress of intestinal microbial metabolites mediated intestinal immunity
Siliao yanjiu, 2023 Animal gut is home to a large number and rich variety of microbial flora. Intestinal microbes and their metabolites are believed to play an important role in regulating the metabolism of animal nutrients and maintaining intestinal immunity.
HAO Xiao-jing +4 more
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